Efficacy of lithium vs. valproate in the treatment of mania in the elderly: A retrospective study

Journal of Clinical Psychiatry

Volumn 60, Issue 3, 1999, Pages 181-186

  Chen, Stephen T ^a,b   Altshuler, Lori L ^a   Melnyk, Kristen A ^a   Erhart, Stephen M ^a   Miller, Elizabeth ^a   Mintz, Jim ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LITHIUM; VALPROIC ACID;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG TOLERABILITY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MANIA; MOOD; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCORING SYSTEM;

EID: 0032946082     PISSN: 01606689     EISSN: None     Source Type: Journal    
DOI: 10.4088/JCP.v60n0306     Document Type: Article

References (29)

1. Young RC, Klerman GL. Mania in late life: focus on age at onset. Am J Psychiatry 1992;149:867-876
2. Eagles JM, Whalley LJ. Ageing and affective disorders: the age at first onset of affective disorders in Scotland, 1969-1978. Br J Psychiatry 1985; 147:180-187
3. Spicer CC, Hare EH, Slater E. Neurotic and psychotic forms of depressive illness: evidence from age-incidence in a national sample. Br J Psychiatry 1973;123:535-541
4. Roth M. The natural history of mental disorder in old age. J Ment Sci 1955;101:281-301
5. Yassa R, Nair V, Nastase C, et al. Prevalence of bipolar disorder in a psychogeriatric population. J Affect Disord 1988;14:197-201
6. Spar JE, Ford CV, Liston EH. Bipolar affective disorder in aged patients. J Clin Psychiatry 1979;40:504-507
7. Himmelhoch JM, Neil JF, May SJ, et al. Age, dementia, dyskinesias, and lithium response. Am J Psychiatry 1980;137:941-945
8. McFarland BH, Miller MR, Straumfjord AA. Valproate use in the older manic patient. J Clin Psychiatry 1990;51:479-481
9. Schou M, Juel-Nielsen N, Stromgren E. The treatment of manic psychosis by the administration of lithium salts. J Neurol Neurosurg Psychiatry 1954;17:250-260
10. Goodwin FK, Murphy DL, Bunney WEJ. Lithium-carbonate treatment in depression and mania: a longitudinal double-blind study. Arch Gen Psychiatry 1969;21:486-496
11. Pope HG Jr, McElroy SL, Keck PE Jr, et al. Valproate in the treatment of acute mania: a placebo-controlled study. Arch Gen Psychiatry 1991;48: 62-68
12. Bowden CL, Brugger AM, Swann AC, et al. for the Depakote Mania Study Group. Efficacy of divalproex vs lithium and placebo in the treatment of mania. J AMA 1994;271:918-924
13. Freeman TW, Clothier JL, Pazzaglia P, et al. A double-blind comparison of valproate and lithium in the treatment of acute mania. Am J Psychiatry 1992;149:108-111
14. Bowden CL. Dosing strategies and time course of response to antimanic drugs. J Clin Psychiatry 1996;57(suppl 13):4-9
15. Bowden CL, Janicak PG, Orsulak P, et al. Relation of serum valproate concentration to response in mania. Am J Psychiatry 1996;153:765-770
16. Guy W. ECDEU Assessment Manual for Psychopharmacology. US Dept Health, Education, and Welfare publication (ADM) 76-338. Rockville, Md: National Institute of Mental Health; 1976:217-222
17. SAS Institute Inc. SAS User's Guide: Statistics. 6th ed. Cary, NC: SAS Institute; 1990
18. Krauthammer C, Klerman GL. Secondary mania: manic syndromes associated with antecedent physical illness or drugs. Arch Gen Psychiatry 1978;35:1333-1339
19. van der Velde CD. Toxicity of lithium carbonate in elderly patients. Am J Psychiatry 1971;127:1075-1077
20. Kahn D, Stevenson E, Douglas CJ. Effect of sodium valproate in three patients with organic brain syndromes. Am J Psychiatry 1988;145: 1010-1011
21. Tonen M, Shulman KI, Satlin A. First-episode mania in late life. Am J Psychiatry 1994;151:130-132
22. Snowdon DA, Greiner LH, Mortimer JA, et al. Brain infarction and the clinical expression of Alzheimer disease: the nun study. JAMA 1997;277: 813-817
23. Cook BL, Shukla S, Hoff AL, et al. Mania with associated organic factors. Acta Psychiatr Scand 1987;76:674-677
24. Secunda SK, Katz MM, Swann A, et al. Mania: diagnosis, state measurement and prediction of treatment response. J Affect Disord 1985;8: 113-121
25. Prien RF, Himmelhoch JM, Kupfer DJ. Treatment of mixed mania. J Affect Disord 1988;15:9-15
26. Keller MB, Lavori PW, Coryell W, et al. Differential outcome of pure manic, mixed/cycling, and pure depressive episodes in patients with bipolar illness. JAMA 1986;255:3138-3142
27. Bowden CL. Predictors of response to divalproex and lithium. J Clin Psychiatry 1995;56(suppl 3):25-30
28. Calabrese JR, Markovitz PJ, Kimmel SE, et al. Spectrum of efficacy of valproate in 78 rapid-cycling bipolar patients. J Clin Psychopharmacol 1992;12:53S-56S
29. Clothier J, Swann AC, Freeman T. Dysphoric mania. J Clin Psychopharmacol 1992;12(1, suppl):3S-16S