Sweetener Augmentation of Serum Triacylglycerol during a Fat Challenge Test in Humans

Journal of the American College of Nutrition

Volumn 18, Issue 2, 1999, Pages 179-185

  Singleton, Michael J ^a   Jamesen, Karen ^a   Mattes, Richard D ^a   Heiser, Carla ^b  

^a PURDUE UNIVERSITY   (United States)

^b INDIANA UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Fructose; Glucose; Human; Taste; Triacylglycerol

Indexed keywords

ASPARTAME; FRUCTOSE; GLUCOSE; LIPOPROTEIN LIPASE; PLACEBO; SWEETENING AGENT; TRIACYLGLYCEROL;

ADULT; AREA UNDER THE CURVE; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN EXPERIMENT; HYPERLIPIDEMIA; INSULIN BLOOD LEVEL; LIPID ANALYSIS; LIPOPROTEIN BLOOD LEVEL; MALE; PALATABILITY; POSTPRANDIAL STATE; TEST MEAL; TRIACYLGLYCEROL BLOOD LEVEL;

ADULT; ASPARTAME; BODY MASS INDEX; DIETARY FATS; FEMALE; FRUCTOSE; GLUCOSE; HUMANS; MALE; SWEETENING AGENTS; TASTE; TRIGLYCERIDES;

EID: 0032944958     PISSN: 07315724     EISSN: 15411087     Source Type: Journal    
DOI: 10.1080/07315724.1999.10718847     Document Type: Article

References (33)

1. Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults: Summary of the Second Report of the National Cholesterol Education Program (CEP) Expert Panel on Detection, Evaluation, Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II). JAMA 269: 3015-3023, 1993.
2. Dubois C, Armand M, Mekki N, Portugal H: Effects of increasing amounts of dietary cholesterol on postprandial lipemia and lipoproteins in human subjects. J Lipid Res 35: 1993-2007, 1994.
3. Groot PHE, van Stiphout WA, Krauss XH, Jansen H, van Tol A, van Ramshorst E, Chin-On S, Hofman A, Cresswell SR, Havekes L: Postprandial lipoprotein metabolism in normolipidemic men with and without coronary artery disease. Arterioscler Thromb 11: 653-662, 1991.
4. Grant KI, Marais MP, Dhansay MA: Sucrose in a lipid-rich meal amplifies the postprandial excursion of serum and lipoprotein triglyceride and cholesterol concentrations by decreasing triglyceride clearance. Am J Clin Nutr 59: 853-860, 1994.
5. Cohen JC, Schall R: Reassessing the effects of simple carbohydrates on the serum triglyceride responses to fat meals. Am J Clin Nutr 48: 1031-1034, 1988.
6. Jeppesen J, Chen Y-D I, Zhou MY, Schaaf P, Coulston A, Reaven GM: Postprandial triglyceride and retinyl ester responses to oral fat: effects of fructose. Am J Clin Nutr 61: 787-791, 1995.
7. Jeppesen J, Chen Y-D I, Zhou MY, Wang T, Reaven GM: Effect of variations in oral fat and carbohydrate load on postprandial lipemia. Am J Clin Nutr 62: 1201-1205, 1995.
8. Cohen JC, Berger GM: Effects of glucose ingestion on postprandial lipemia and triglyceride clearance in humans. J Lipid Res 31: 597-602, 1990.
9. Albrink MJ, Fitzgerald JR, Man EB: Reduction of alimentary lipemia by glucose. Metabolism 17: 162-171, 1958.
10. Mann JI, Truswell AS, Pimstone BL: The different effects of oral sucrose and glucose on alimentary lipaemia. Clin Sci 41: 123-129, 1971.
11. Nikkila EA, Pelkonen R: Enhancement of alimentary hyperglyceridemia by fructose and glycerol in man. Proc Soc Exp Biol Med 123: 91-94, 1966.
12. Truswell AS: Food carbohydrates and plasma lipids-an update. Am J Clin Nutr 59 (suppl): 710S-718S, 1994.
13. Park YK, Yetley EA: Intakes of food sources of fructose in the United States. Am J Clin Nutr 58(Suppl): 737S-747S, 1993.
14. Hallfrisch J: Metabolic effects of dietary fructose. FASEB J 4: 2652-2660, 1990.
15. Ramirez I: Oral stimulation alters digestion of intragastric oil meals in rats. Am J Physiol 248: 459-463, 1985.
16. Moskowitz HR: The psychology of sweetness. In Sipple H, McNutt KW (eds): “Sugars in Nutrition,” New York: Academic Press, pp 37-64, 1974.
17. Cohen JC, Noakes TD, Spinnler Benade AJ: Serum triglyceride responses to fatty meals: effects of meal fat content. Am J Clin Nutr 47: 825-827, 1988.
18. Schiffman S, Reilly DA, Clark TB: Qualitative differences among sweeteners. Physiol Behav 23: 1-8, 1979.
19. Eating Pattern Assessment Tool, Version 3. Dept of Med and Div of Epidemiol, University of Minnesota, 1990.
20. Sensory Evaluation Division of the Institute of Food Technologists: Sensory evaluation guide for testing food and beverage products and guidelines for the preparation and review of papers reporting sensory evaluation data. Food Technol 35(11): 50-59, 1981.
21. Harris H, Kalmus H: Chemical specificity in genetical differences of taste sensitivity. Ann Eugen 15: 32-45, 1949.
22. SPSS Inc. SPSS 6.12 for Windows. Chicago: SPSS Inc. 1994.
23. Sadur CN, Eckel RH: Insulin stimulation of adipose tissue lipoprotein lipase: Use of the euglycemic clamp technique. J Clin Invest 69: 1119-1125, 1982.
24. Reaven GM, Chen Y-DI: Role of insulin in regulation of lipoprotein metabolism in diabetes. Diabetes Metab Rev 4: 639-652, 1988.
25. Blades B and Garg A: Mechanisms of increase in plasma triacylglycerol concentrations as a result of high carbohydrate intakes in patients with non-insulin-dependent diabetes mellitus. Am J Clin Nutr 62: 996-1002, 1995.
26. Jackson RL, Yates MT, McNerney CA, Kashyap ML: Relationship between post-heparin plasma lipases, triglycerides and high density lipoproteins in normal subjects. Horm Metab Res 22: 289-294, 1990.
27. Gannon MC, Nuttall FQ, Westphal SA and Seaquist ER: The effect of fat and carbohydrate on plasma glucose, insulin, C-peptide, and triglycerides in normal male subjects. J Am Col Nutr 12: 36-41, 1993.
28. Den Besten L, Reyna RH, Connor WE, Stegink LD: The different effects on the serum lipids and fecal steroids of high carbohydrate diets given orally or intravenously. J Clin Invest 52: 1384-1393, 1973.
29. Teff KL, Devine J, Engelman K: Sweet taste: Effect on cephalic phase insulin release in men. Physiol & Behav 57: 1089-1095, 1995.
30. Abdallah L, Chabert M, Louis-Sylvestre J: Cephalic phase responses to sweet taste. Am J Clin Nutr 65: 737-743, 1997.
31. Kun E, Horvath I: The influence of oral saccharin on blood sugar. Proc Soc Exp Biol 66: 175-179, 1947.
32. Teff KL, Engelman K: Oral sensory stimulation improves glucose tolerance in humans: effects on insulin, C-peptide, and glucagon. Am J Physiol 270: R1371-R1379, 1996.
33. Mattes RD. Physiologic responses to sensory stimulation by food: Nutritional implications. J Am Diet Assoc 97: 406-410, 1997.