Syntheses and β-adrenergic binding affinities of (R)- and (S)- fluoronaphthyloxypropanolamines

Chirality

Volumn 11, Issue 2, 1999, Pages 144-148

  Adejare, Adeboye ^a   Deal, Stacey A ^a   Day Jr , Michael S ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

Author keywords

adrenoceptor ligands; Aryloxypropanolamine; Enantioselective synthesis; Fluoroaromatic; Naphthyloxypropanolamine

Indexed keywords

3 (4' FLUORO 1' NAPHTHYLOXY) 1 (TERT BUTYLAMINO) 2 PROPANOL; 3 (4' FLUORO 1' NAPHTHYLOXY) 1,2 EPOXYPROPANE; BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; FLUORONAPHTHYLOXYPROPANOLAMINE DERIVATIVE; GLYCIDYL 3 NITROBENZENESULFONE; PROPANOLAMINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BRONCHODILATATION; CHIRALITY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; ENANTIOMER; HEART RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIPOLYSIS; PRIORITY JOURNAL; STEREOCHEMISTRY;

ADRENERGIC BETA-ANTAGONISTS; ANIMALS; NAPHTHALENES; PROPANOLAMINES; RATS; RECEPTORS, ADRENERGIC, BETA; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032944498     PISSN: 08990042     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1520-636X(1999)11:2<144::AID-CHIR11>3.0.CO;2-I     Document Type: Article

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