Changes in the concentration of insulin-like growth factor I and transforming growth factor β1 in rat femoral bone during growth

Calcified Tissue International

Volumn 64, Issue 1, 1999, Pages 78-82

  Pfeilschifter, J ^a   Erdmann, J ^a   Storch, S ^a   Ziegler, R ^a   Weinreb, M ^b  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b TEL AVIV UNIVERSITY   (Israel)

Author keywords

Bone matrix; Growth; Insulin like growth factor I; Rat; Transforming growth factor

Indexed keywords

GROWTH FACTOR; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; BONE GROWTH; BONE MASS; FEMUR; GROWTH REGULATION; IMMUNOREGULATION; MALE; NEWBORN; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN CONTENT; RAT;

AGING; ANIMALS; BONE DENSITY; FEMUR; INSULIN-LIKE GROWTH FACTOR I; MALE; RATS; TRANSFORMING GROWTH FACTOR BETA;

EID: 0032943559     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002239900582     Document Type: Article

References (28)

1. Matkovic V (1996) Skeletal development and bone turnover revisited. J Clin Endocrinol Metab 81:2013-2015
2. Matkovic V, Jelic T, Wardlaw GM, Ilich JZ, Goel PK, Wright JK, Andon MB, Smith KT, Heaney RP (1994) Timing of peak bone mass in Caucasian females and its implication for the prevention of osteoporosis. Inference from a cross-sectional model. J Clin Invest 93:799-808
3. Bonjour JP, Theintz G, Law F, Slosman D, Rizzoli R (1994) Peak bone mass. Osteoporosis Int 4(suppl)1:7-13
4. Seeman E (1994) Reduced bone density in women with fractures: contribution of low peak bone density and rapid bone loss. Osteoporosis Int 4(suppl 1):15-25
5. Baylink DJ, Finkleman RD, Mohan S (1993) Growth factors to stimulate bone formation. J Bone Miner Res 8(suppl 2):S565-S572
6. Schmid C (1993) IGFs: function and clinical importance. II. The regulation of osteoblast function by hormones and cytokines with special reference to insulin-like growth factors and their binding proteins. J Int Med 234:535-542
7. Rosen CJ, Donahue LR, Hunter SJ (1994) Insulin-like growth factors and bone: the osteoporosis connection. Proc Soc Exp Biol Med 206:83-102
8. Centrella M, Horowitz MC, Wozney JM, McCarthy TL (1994) Transforming growth factor-β gene family members and bone. Endocrine Rev 15:27-39
9. Bonewald LF, Dallas SL (1994) Role of active and latent transforming growth factor β in bone formation. J Cell Biochem 55:350-357
10. Carrington JL, Roberts AB, Flanders KC, Roche NS, Reddi AH (1988) Accumulation, localization, and compartmentation of transforming growth factor beta during endochondral bone development. J Cell Biol 107:1969-1975
11. Bortell R, Barone LM, Tassinari MS, Lian JB, Stein GS (1990) Gene expression during endochondral bone development: evidence for coordinate expression of transforming growth factor β1 and collagen type I. J Cell Biochem 44:81-91
12. Turner RT, Spelsberg TC (1991) Correlation between mRNA levels for bone cell proteins and bone formation in long bones of maturing rats. Am J Physiol 261:E348-E353
13. Holmes SJ, Shalet SM (1996) Role of growth hormone and sex steroids in achieving and maintaining normal bone mass. Horm Res 45:86-93
14. Pfeilschifter J, Laukhuf F, Müller-Beckmann B, Blum WF, Pfister T, Ziegler R (1995) Parathyroid hormone increases the concentration of insulin-like growth factor-I and transforming growth factor beta 1 in rat bone. J Clin Invest 96:767-774
15. Nguyen-Yamamoto L, Deal CL, Finkelstein JA, van Vliet G (1994) Hormonal control of growth in the genetically obese Zucker rat. I. Linear growth, plasma insulin-like growth factor-I (IGF-I) and IGF-binding proteins. Endocrinology 134: 1382-1388
16. Bikle DD, Harris J, Halloran BP, Roberts CT, LeRoith D, Morey-Holton E (1994) Expression of the genes for insulin-like growth factors and their receptors in bone during skeletal growth. Am J Physiol 267:E278-E286
17. Shinar DM, Endo N, Halperin D, Rodan GA, Weinreb M (1993) Differential expression of insulin-like growth factor-I (IGF-I) and IGF-II messenger ribonucleic acid in growing rat bone. Endocrinology 132:1158-1167
18. Blum WF, Breier BH (1994) Radioimmunoassays for IGFs and IGFBPs. Growth Regul 4(suppl 1):11-19
19. Bang P (1995) Valid measurements of total IGF concentrations in biological fluids. Recommendations from the 3rd Int Symp on insulin-like growth factors. Endocrinology 136:816-817
20. Jennings JC, Mohan S (1990) Heterogeneity of latent transforming growth factor-β isolated from bone matrix proteins. Endocrinology 126:1014-1021
21. Pfeilschifter J, Diel I, Scheppach B, Bretz A, Krempien R, Erdmann J, Schmid G, Reske N, Bismar H, Seck T, Krempien B, Ziegler R (1998) Concentration of transforming growth factor beta in human bone tissue: relationship to age, menopause, bone turnover and bone volume. J Bone Miner Res 13:716-730
22. Sontag W (1986) Quantitative measurements of periosteal and cortical-endosteal bone formation and resorption in the midshaft of male rat femur. Bone 7:63-70
23. Gray TK, Flynn TC, Gray KM, Nabell LM (1987) 17-β estradiol acts directly on the clonal osteoblastic cell line UMR-106. Proc Natl Acad Sci USA 84:6267-6270
24. Oursler MJ, Cortese C, Keeting P, Riggs L, Spelsberg TC (1991) Modulation of TGF-β production in normal human osteoblast-like cells by 17-β estradiol and parathyroid hormone. Endocrinology 129:3313-3320
25. Benz DJ, Haussler MR, Thomas MA, Speelman B, Komm BS (1991) High-affinity androgen binding and androgenic regulation of A1(I)-procollagen and transforming growth factor-β steady state messenger ribonucleic acid levels in human osteoblast-like osteosarcoma cells. Endocrinology 128:2723-2730
26. Nicolas V, Prewett A, Bettica P, Mohan S, Finkelman RD, Baylink DJ, Farley JR (1994) Age-related decreases in insulin-like growth factor-I and transforming growth factor-beta in femoral cortical bone from both men and women: implications for bone loss with aging. J Clin Endocrinol Metab 78:1011-1016
27. Dequeker J, Mohan S, Finkelman RD, Aerssens J, Baylink DJ (1993) Generalized osteoarthritis associated with increased insulin-like growth factor types I and II and transforming growth factor beta in cortical bone from the iliac crest. Possible mechanism of increased bone density and protection against osteoporosis. Arthritis Rheum 36:1702-1708
28. Seck T, Scheppach B, Diel I, Bismar H, Krempien B, Ziegler R, Pfeilschifter J (1997) Insulin-like growth factors in human bone matrix: association with age, menopause and cancellous bone volume. Bone 20(suppl):7S.