Insulin-like growth factor binding protein-1 as a predictor of glucose- stimulated hyperinsulinemia in prepubertal obese children

European Journal of Endocrinology

Volumn 140, Issue 3, 1999, Pages 231-234

  Saitoh, Hisako ^a   Kamoda, Tomohiro ^a   Nakahara, Satoko ^b   Hirano, Takeki ^c   Matsui, Akira ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b Kensei General Hospital   (Japan)

^c Ibaraki Children's Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; SOMATOMEDIN BINDING PROTEIN 1;

AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DIET RESTRICTION; EARLY DIAGNOSIS; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; HUMAN TISSUE; HYPERINSULINEMIA; INSULIN RESISTANCE; NORMAL HUMAN; OBESITY; ORAL GLUCOSE TOLERANCE TEST; PREDICTION; PREPUBERTY; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SCHOOL CHILD;

EID: 0032943398     PISSN: 08044643     EISSN: None     Source Type: Journal    
DOI: 10.1530/eje.0.1400231     Document Type: Article

References (16)

1. Waliul Islam AHM, Yamashita S, Kotani K, Nakamura T, Tokunaga K, Aral T et al. Fasting plasma insulin level is an important risk factor for the development of complications in Japanese obese children. Metabolism 1995 44 478-485.
2. Le Stunff C & Bougnères P. Early changes in postprandial insulin secretion, not in insulin sensitivity, characterize juvenile obesity. Diabetes 1994 43 696-702.
3. Brismar K, Fernqvist-Forbes E, Wahren J & Hall K. Effect of insulin on the hepatic production of insulin-like growth factor-binding protein-1 (IGFBP-1), IGFBP-3, and ICF-I in insulin-dependent diabetes. Journal of Clinical Endocrinology and Metabolism 1994 79 872-878.
4. Conover CA, Lee PDK, Kanaley JA, Clarkson JT & Jensen MD. Insulin regulation of insulin-like growth factor binding protein-1 in obese and nonobese humans. Journal of Clinical Endocrinology and Metabolism 1992 74 1355-1360.
5. Mogul HR, Marshall M, Frey M, Burke HB, Wynn PS, Wilker S et al. Insulin like growth factor-binding protein-1 as a marker for hyperinsulinemia in obese menopausal women. Journal of Clinical Endocrinology and Metabolism 1996 81 4492-4495.
6. Saitoh H, Kamoda T, Nakahara S, Hirano T & Nakamura N. Serum concentrations of insulin, insulin-like growth factor (IGF)-I, IGF binding protein (IGFBP)-1 and -3 and growth hormone binding protein in obese children: fasting IGFBP-1 is suppressed in normoinsulinaemic obese children. Clinical Endocrinology 1998 48 487-492.
7. The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Report of the expert committee on the diagnosis and classification of diabetes inellitus. Diabetes Care 1997 20 1183-1197.
8. Haffner SM, Stern MP, Hazuda HP, Pugh JA & Patterson JK. Hyperinsulinemia in a population at high risk for non-insulin-dependent diabetes mellitus. New England Journal of Medicine 1986 315 220-224.
9. Amiel SA, Sherwin RS, Simonson DC, Lauritano AA & Tamborlane WV Impaired insulin action in puberty. A contributing factor to poor glycemic control in adolescents with diabetes. New England Journal of Medicine 1986 315 215-219
10. Bloch CA, Clemons P & Sperling MA. Puberty decreases insulin sensitivity. Journal of Pediatrics 1987 110 481-487.
11. Traverse SH, Jeffers BW, Blooch CA, Hill JO & Eckel RH. Gender and Tanner stage differences in body composition and insulin sensitivity in early pubertal children. Journal of Clinical Endocrinology and Metabolism 1995 80 172-178.
12. Lee PDK, Conover CA & Powell DR. Regulation and function of insulin-like growth factor-binding protein-1. Proceedings of the Society for Experimental Biology and Medicine 1993 204 4-29.
13. Brismar K, Grill V, Efendic S & Hall K. The insulin-like growth factor binding protein-1 in low and high insulin responders before and during dexamethasone treatment. Metabolism 1991 40 728-752.
14. Hellénius MB, Brismar KE, Berglund BH & De Faire UH. Effects of glucose tolerance, insulin secretion, insulin-like growth factor 1 and its binding protein, IGFBP-1, in a randomized controlled diet and exercise study in healthy, middle-aged men. Journal of Internal Medicine 1995 238 121-130.
15. Reaven GM, Moore J & Greenfield M. Quantification of insulin secretion and in vivo insulin action in nonobese and moderately obese individuals with normal glucose tolerance. Diabetes 1983 32 600-604.
16. Morris DV & Falcone T. The relationship between insulin sensitivity and insulin-like growth factor-binding protein-1. Gynecological Endocrinology 1996 10 407-412.