Cloning and molecular characterization of Hev b 3, a spina-bifida-associated allergen from Hevea brasiliensis latex

International Archives of Allergy and Immunology

Volumn 118, Issue 2-4, 1999, Pages 311-312

  Scheiner, Otto ^d   Wagner, B ^e   Wagner, S ^e   Krebitz, M ^e   Crameri, R ^a   Niggemann, B ^b   Yeang, H Y ^c   Ebner, C ^e   Breiteneder, H ^e  

^a SWISS INSTITUTE OF ALLERGY AND ASTHMA RESEARCH SIAF   (Switzerland)

^b HUMBOLDT UNIVERSITY   (Germany)

^c RUBBER RESEARCH INSTITUTE OF MALAYSIA   (Malaysia)

^d MEDICAL UNIVERSITY OF VIENNA   (Austria)

^e NONE

Author keywords

Allergy; cDNA; Hevea brasiliensis; IgE; Latex; Recombinant allergen; Spina bifida

Indexed keywords

ALLERGEN; COMPLEMENTARY DNA; LATEX; RECOMBINANT PROTEIN;

CONFERENCE PAPER; DNA SEQUENCE; IMMEDIATE TYPE HYPERSENSITIVITY; MOLECULAR CLONING; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; SPINA BIFIDA;

EID: 0032943356     PISSN: 10182438     EISSN: None     Source Type: Journal    
DOI: 10.1159/000024113     Document Type: Conference Paper

References (13)

1. Slater JE: Latex allergy. J Allergy Clin Immunol 1994;94:139-149.
2. Turjanmaa K, Alenius H, Mäkinen-Kiljunen S, Reunala T, Palosuo T: Natural rubber latex allergy. Allergy 1996;51:593-602.
3. Michael T, Niggemann B, Moers A, Seidel U, Wahn U, Scheffner D: Risk factors for latex allergy in patients with spina bifida. Clin Exp Allergy 1996;26:934-939.
4. Nieto A, Estornell F, Mazón A, Reig C, Nieto A, García-Ibarra F: Allergy to latex in spina bifida: A multivariate study of associated factors in 100 consecutive patients. J Allergy Clin Immunol 1996;98:501-507.
5. Cremer R, Hoppe A, Korsch E, Kleine-Diepenbruck U, Bläker F: Natural rubber latex allergy: Prevalence and risk factors in patients with spina bifida compared with atopic children and controls. Eur J Pediatr 1998;157: 13-16.
6. Konz KR, Chia JK, Kurup VP, Resnick A, Kelly KJ, Fink JN: Comparison of latex hypersensitivity among patients with neurological defects. J Allergy Clin Immunol 1995;95:950-954.
7. Czuppon AB, Chen Z, Rennert S, Engelke T, Meyer HE, Heber M, Baur X: The rubber elongation factor of rubber trees (Hevea brasiliensis) is the major allergen in latex. J Allergy Clin Immunol 1993;92:690-697.
8. Attanyaka DP, Kekwick RG, Franklin FC: Molecular cloning and nucleotide sequencing of the rubber elongation factor gene from Hevea brasiliensis. Plant Mol Biol 1991;16: 1079-1081.
9. Alenius H, Palosuo T, Kelly K, Kurup V, Reunala T, Mäkinen-Kiljunen S, Turjanmaa K, Fink J: IgE reactivity to 14-kD and 27-kD natural rubber proteins in latex-allergic children with spina bifida and other congenital abnormalities. Int Arch Allergy Immunol 1993;102: 61-66.
10. Alenius H, Kalkkinen N, Lukka M, Turjanmaa K, Reunala T, Mäkinen-Kiljunen S, Palosuo T: Purification and partial amino acid sequencing of a 27-kD natural rubber allergen recognized by latex-allergic children with spina bifida. Int Arch Allergy Immunol 1995;106:258-262.
11. Yeang HY, Cheong KF, Sunderasan E, Hamzah S, Chew NP, Hamid S, Hamilton RG, Cardosa MJ: The 14.6-kD rubber elongation factor (Hev b 1) and 24-kD (Hev b 3) rubber particle proteins are recognized by IgE from patients with spina bifida and latex allergy. J Allergy Clin Immunol 1996;98:628-639.
12. Lu LJ, Kurup VP, Hoffman DR, Kelly KJ, Murali PS, Fink JN: Characterization of a major latex allergen associated with hypersensitivity in spina bifida patients. J Immunol 1995;155: 2721-2728.
13. Yeang HY, Ward MA, Zamri ASM, Dennis MS, Light DR: Amino acid sequence similarity of Hev b 3 to two previously reported 27- and 23-kD latex proteins allergenic to spina bifida patients. Allergy 1998;53:513-519.