Suppression of T1-receptor expression by antisense RNA abrogates differentiation of osteogenic osteosarcoma cells

Laboratory Investigation

Volumn 79, Issue 5, 1999, Pages 529-536

  Werenskiold, Anne Katrin ^a   Schmidt, Jörg ^b   Rupp, Brigitte ^a   Gössner, Wolfgang ^b   Höfler, Heinz ^a,b  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; COLLAGEN TYPE 1; COMPLEMENTARY RNA; INTERLEUKIN 1 RECEPTOR; OSTEOCALCIN; RECEPTOR SUBTYPE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; CELL DIFFERENTIATION; CELL PROLIFERATION; GENE EXPRESSION REGULATION; MOUSE; NONHUMAN; OSTEOSARCOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; CELL DIFFERENTIATION; CORE BINDING FACTOR ALPHA 1 SUBUNIT; DOWN-REGULATION; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; NEOPLASM PROTEINS; OSTEOGENESIS; OSTEOSARCOMA; PROTEIN BIOSYNTHESIS; PROTEINS; RNA, ANTISENSE; RNA, MESSENGER; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

EID: 0032942052     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Casser-Bette M, Murray AB, Closs EI, Erfle V, and Schmidt J (1990). Bone formation by osteoblast-like cells in a three-dimensional cell culture. Calcif Tissue Int 46:46-56.
2. Chomczynski P and Sacchi N (1987). Single step method of RNA isolation by acid guanidinium thiocyanate-phenolchloroform extraction. Anal Biochem 162:156-159.
3. Chu ML, Myers JC, Bernard MP, Ding JF, and Ramirez F (1982). Cloning and characterisation of five overlapping cDNAs specific for the human proalpha1 (I) collagen chain. Nucl Acids Res 10:5925-5934.
4. Ducy P, Zhang R, Geoffroy V, Ridall AM, and Karsenty G (1997). Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation. Cell 89:747-754.
5. Fort P, Piechaczyk M, El Sabrouty S, Dani C, Jeanteur P, and Blanchard JM (1985). Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family. Nucl Acids Res 13:327-334.
6. Garnero P, Sornay-Rendu E, Chapuy M-C, and Delmas PD (1996). Increased bone turnover in late postmenopausal women is a major determinant of osteoporosis. J Bone Miner Res 11:337-348.
7. Gayle MA, Slack JL, Bonnert TP, Renshaw BR, Sonoda G, Taguchi T, Testa JR, Dower SK, and Sims JE (1996). Cloning of a putative ligand for the T1/ST2 receptor. J Biol Chem 271:5784-5789.
8. Hauschka PV, Mavrakos AE, Iafrati MD, Doleman SF, and Klagsbrun M (1986). Growth factors in bone matrix. J Biol Chem 261:12665-12674.
9. Heermeier K, Spanner M, Träger J, Gradinger R, and Schmidt J (1995). Bone formation of human osteoblast-like cells in a three-dimensional (3-D) cell culture: An in vitro model for studies of skeletal disorders. Cells Mater 5:309-321.
10. Horowitz MC (1993). Cytokines and estrogen in bone: Anti-osteoporotic effects. Science 260:626-627.
11. Jaggi R, Salmons B, Muellener D, and Groner B (1986). The v-mos and H-ras oncogene expression represses glucocorticoid-hormone dependent transcription from the mouse mammary tumor virus LTR. EMBO J. 5:2609-2616.
12. Klemenz R, Hoffmann S, and Werenskiold AK (1989). Serum-and oncoprotein-mediated induction of a gene with similarity to carcinoembryonic antigen. Proc Natl Acad Sci USA 86: 5708-5712.
13. Komori T, Yagi H, Nomura, S, Yamaguchi A, Sasaki K, Deguchi K, Shimizu Y, Bronson RT, Gao Y-H, Inada M, Sato M, Okamato R, Kitamura Y, Yoshiki S, and Kishimoto T (1997). Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell 89:755-764.
14. Löhning M, Stroehmann A, Coyle A, Grogan JL, Lin S, Gutierrez-Ramos JC, Levinson D, Radbruch A, and Kamradt T (1998). T1/ST2 is preferentially expressed on murine Th2 cells, independent of IL-4-, IL-5, and IL-10 and important for Th2 effector function. Proc Natl Acad Sci USA 95:6930-6936.
15. Lorenzo JA (1991). The role of cytokines in the regulation of local bone resorption. Crit Rev Immunol 11:195-213.
16. Owen TA, Aronow M, Shalhoub V, Barone LM, Wilming L, Tassinari MS, Kennedy MB, Pockwinse S, Lian JB, and Stein GS (1990). Progressive development of the rat osteoblast phenotype in vitro: Reciprocal relationsships in expression of genes associated with osteoblast proliferation and differentiation during formation of the bone extracellular matrix. J Cell Physiol 143:420-430.
17. Pacifici R (1996). Estrogen, cytokines, and pathogenesis of postmenopausal osteoporosis. J Bone Miner Res 11:1043-1051.
18. Rössler U, Andres AC, Reichmann E, Schmahl W, and Werenskiold AK (1993). Expression of T1, a CEA family member, in mammary carcinomas of WAP-ras transgenic mice. Oncogene 8:609-617.
19. Rössler U, Thomassen E, Hültner L, Baier S, Danescu J, and Werenskiold AK (1995). Secreted and membrane-bound isoforms of T1, an orphan receptor related to IL-1 binding proteins, are differently expressed in vivo. Dev Biol 168:86-97.
20. Rupp B, Lorenz U, Schmidt J, and Werenskiold AK (1998). Discordant effects of AP-1 transcription factor on gene regulation, invasion, and metastasis in spontaneous, radiation-induced, and fos-induced osteosarcomas. Mol Carcinog 23: 69-75.
21. Schaub RG and Wozney J (1991). Novel agents that promote bone regeneration. Curr Opin Biotechnol 2:868-871.
22. Schmidt J, Strauss PG, Schön A, Luz A, Murray AB, Melchiori A, Aresu O, and Erfle V (1988). Establishment and characterization of osteogenic cell lines from a spontaneous murine osteosarcoma. Differentiation 39:151-160.
23. Stein GS, Lian JB, Stein JL, van Wijnen A, and Montecino M (1996). Transcriptional control of osteoblast growth and differentiation. Physiol Rev 76:593-629.
24. Strauss PG, Closs EI, Schmidt J, and Erfle V (1990). Gene expression during osteogenic differentiation in mandibular condyles in vitro. J Cell Biol 110:1369-1378.
25. Thomassen E, Kothny G, Haas S, Danescu J, Hültner L, Dörmer P, and Werenskiold AK (1995). Role of celltype-specific promoters in the developmental regulation of T1, an interleukin-1 receptor homologue. Cell Growth Differ 6:178-184.
26. Weiss MJ, Henthorn PS, Lafferty MA, Slaughter C, Raducha M, and Harris H (1986). Isolation and characterization of a cDNA encoding human liver/bone/kidney-type alkaline phosphatase. Proc Natl Acad Sci USA 83:7182-7186.
27. Werenskiold AK (1992). Characterisation of a mitogen-and oncogene-inducible secreted glycoprotein of the immunoglobulin superfamily. Eur J Biochem 204:1041-1047.
28. Werenskiold AK, Rössler U, Löwel M, Schmidt J, Heermeier K, Spanner M, and Strauss PG (1995). Bone matrix deposition of T1, a homologue of interleukin-1 receptors. Cell Growth Differ 6:171-177.
29. Xu D, Chan WL, Leung BP, Huang F, Wheeler R, Piedrafita D, Robinson JH, and Liew FY (1998). Selective expression of a stable cell surface molecule on type 2 but not type 1 helper T cells. J Exp Med. 187:787-794.