Improved efficacy of a microencapsulated macrophage colony stimulating factor and methotrexate in melanoma

Drug Development and Industrial Pharmacy

Volumn 25, Issue 5, 1999, Pages 583-590

  D'Souza, Martin J ^a   Pourfarzib, Ramin ^a  

^a MERCER UNIVERSITY   (United States)

Author keywords

B 16 malignant melanoma; IL 1 ; Macrophages; Methotrexate; Polylactic co glycolic acid; Recombinant human macrophage colony stimulating factor; TNF

Indexed keywords

COLONY STIMULATING FACTOR 1; INTERLEUKIN 1BETA; METHOTREXATE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CHEMOTHERAPY; DRUG EFFICACY; DRUG FORMULATION; MALE; MELANOMA; MOUSE; NONHUMAN;

ANIMALS; HUMANS; INTERLEUKIN-1; MACROPHAGE COLONY-STIMULATING FACTOR; MALE; MELANOMA, EXPERIMENTAL; METHOTREXATE; MICE; MICE, INBRED C57BL; MICROSPHERES; RECOMBINANT PROTEINS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0032941902     PISSN: 03639045     EISSN: None     Source Type: Journal    
DOI: 10.1081/DDC-100102212     Document Type: Article

References (32)

1. D. D. Shen and D. L. Azarnoff, Clinical pharmacokinetics of methotrexate, Clin. Pharmacokinet., 3, 1-13 (1978).
2. J. R. Bertino, The mechanism of action of the folate antagonists in man, Cancer Res., 23, 1286-1306 (1963).
3. E. M. Hersh, G. Vernon, S. H. Edward, and J. E. Freireich, Hepatotoxic effects of methotrexate, Cancer, 19, 600-606 (1966).
4. W. A. Bleyer, The clinical pharmacology of methotrexate, Cancer, 41, 36-51 (1978).
5. D. A. Boetcher and E. J. Leonard, Abnormal monocyte chemotactic response in cancer patients, J. Natl. Cancer Inst., 52, 1091-1099 (1974).
6. N. S. Bock, R. B. Cameron, P. Kragel, J. Mule, and S. A. Rosenberg, Biological and antitumor effects of recombinant human macrophage colony-stimulating factor in mice, Cancer Res., 51, 2649-2654 (1991).
7. J. Horiguchi, E. Sariban, and D. Kufe, Transcriptional and posttranscriptional regulation of CSF-1 gene expression in human monocytes, Mol. Cell. Biol., 8, 3951 (1988).
8. G. G. Wong, J. S. Witek, P. A. Temple, et al., Human GM-CSF: Molecular cloning of the complementary DAN and purification of the natural and recombinant protein, Science, 228, 810-815 (1985).
9. S. J. Brandt, W. P. Peters, S. K. Atwater, J. Kurtzberg, M. J. Borowitz, and R. B. Jones, Effect of recombinant human macrophage colony-stimulating factor on hematopoietic reconstitution after high-dose chemotherapy and autologous bone marrow transplantation, N. Engl. J. Med., 318, 869-876 (1988).
10. S. C. Clark and R. Kamen, The human hematopoietic colony stimulating factors, Science, 236, 1229-1237 (1987).
11. S. K. Das and E. R. Stanley, Structure-function studies of a colony stimulating factor (CSF-1), J. Biol. Chem., 257, 13679-13684 (1982).
12. M. J. Thomassen, B. P. Barna, H. P. Wiedemann, and M. Ahmad, Modulation of human alveolar macrophages tumoricidal activity by recombinant macrophages colony stimulating factor, J. Biol. Resp. Modifiers, 9, 87-91 (1990).
13. D. A. Hume, R. E. Donahue, and I. J. Fidler, The therapeutic effect of human recombinant macrophage colony stimulating factor in experimental murine metastatic melanoma, Lymphokine Res., 8, 69-77 (1989).
14. M. J. D'Souza, Controlled release of cyclosporine from microspheres, Drug Dev. Ind. Pharm., 14, 1351 (1988).
15. P. K. Gupta and C. T. Hung, Albumin microspheres II: applications in drug delivery, J. Microencapsulation, 6, 463-472 (1989).
16. R. Pourfarzib and M. J. D'Souza, Preparation of albumin microspheres containing macrophage colony stimulating factor, Pharm. Res., 9, S-68 (1992).
17. R. Pourfarzib, D. Gajjar, I. Riadi, J. Oliver, and M. J. D'Souza, Enzyme linked immunosorbent assay for detection of human tumor necrosis factor alpha, Pharm. Res., 10, S-1-400 (1993).
18. R. Pourfarzib, D. Gajjar, I. Riadi, J. Oliver, and M. J. D'Souza, Enzyme linked immunosorbent assay for detection of human interleukin-1 beta, Pharm. Res., 10, S-1-400 (1993).
19. A. Sampson-Johannes and J. A. Carlino, Enhancement of human monocyte tumoricidal activity by recombinant M-CSF, J. Immunol. 141, 3680-3686 (1988).
20. H. Yamada, S. Iwase, M. Mohri, and D. Kufe, Involvement of a nuclear factor-kB-like protein in induction of the macrophage colony-stimulating factor gene by tumor necrosis factor, Blood, 78, 1988-1995 (1991).
21. E. L. Racoosin and J. A. Swanson, Macrophage colony-stimulating factor (rM-CSF) stimulates pinocytosis in bone marrow-derived macrophages, J. Exp. Med., 170, 1635 (1989).
22. Y. Tabata and Y. Ikada, Drug delivery systems for antitumor activation of macrophages, Ther. Drug Carrier Sys., 7, 121-148 (1990).
23. P. DeSouza, D. Eshima, and M. J. D'Souza, In-vivo uptake studies of polylactic co-glycolic acid microspheres in normal and arthritic rats after i.p. administration, Pharm. Res., 7, S-39 (1990).
24. P. DeSouza, D. Eshima, and M. J. D'Souza, In-vivo uptake studies of amino modified polystyrene latex microspheres in normal and arthritic rats after i.p. administration, Pharm. Res., 7, S-174 (1990).
25. M. J. D'Souza, S. Uraizee, and D. Eshima, In-vitro uptake of radiolabeled tyrosine-PLGA microspheres by the macrophages, Pharm. Res., 8, S-262 (1991).
26. M. J. D'Souza, S. Uraizee, and D. Eshima, In-vivo uptake of Tc-99m labeled tyrosine-PLGA microspheres in the blood after i.p. administration, Pharm. Res., 8, S-262 (1991).
27. C. S. Marcus, J. H. Kuperus, J. A. Butler, P. L. Henneman, R. D. Salk, B. Y. Chen, M. R. P. Vivian, and L. M. Yamanaka, Phagocytic labelling of leukocytes with 99m Tc-albumin colloid for nuclear imaging, Nucl. Med. Biol., 15, 673-682 (1988).
28. G. B. Saha, D. H. I. Feiglin, J. K. O'Donnell, R. T. Go, P. M. Karam, and W. Macintyre, Experience with technetium-99m albumin colloid kit for reticuloendothelial system imaging, Radiopharmacy, 14, 149-151(1896).
29. G. V. Taplin, D. E. Johnson, E. K. Dore, et al., Lung photoscans with macroaggregates of human serum albumin: Experimental basis and clinical trials, Health Phys., 10, 1219-1227 (1964).
30. Y. Tabata and Y. Ikada, Synthesis of gelatin microspheres containing interferon, Pharm. Res., 6, 422 (1989).
31. C. A. Dinarello, Interleukin-1, Rev. Infect. Dis., 6, 51-95 (1984).
32. J. H. Freimann and A. B. Markowitz, Cytokines and chemotherapy: A new approach to therapy for solid tumors, Cancer Bull., 43, 224-232 (1991).