Sepsis attenuates the intensity of the neuromuscular blocking effect of d-tubocurarine and the antagonistic actions of neostigmine and edrophonium accompanying depression of muscle contractility of the diaphragm

Acta Anaesthesiologica Scandinavica

Volumn 43, Issue 2, 1999, Pages 196-201

  Narimatsu, Eichi ^a   Nakayama, Y ^a   Sumita, S ^a   Iwasaki, H ^a   Fujimura, N ^a   Satoh, K ^a   Namiki, A ^a  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Antagonists, neuromuscular relaxants: neostigmine, edrophonium; Neuromuscular relaxants: d tubocurarine; Neuromuscular transmission: drug interaction; Sepsis

Indexed keywords

EDROPHONIUM; NEOSTIGMINE; TUBOCURARINE CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENUATION; BACTERIAL PERITONITIS; CONTROLLED STUDY; DIAPHRAGM MUSCLE; INFLAMMATION; MALE; MUSCLE CONTRACTILITY; MUSCLE EXCITATION; MUSCLE ISOMETRIC CONTRACTION; MUSCLE TONE; NEUROMUSCULAR TRANSMISSION; NONHUMAN; PHRENIC NERVE; PRIORITY JOURNAL; RAT; SEPSIS;

EID: 0032941533     PISSN: 00015172     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-6576.1999.430213.x     Document Type: Article

References (15)

1. 1. Hoyt JW. Persistent paralysis in critically ill patients after the use of neuromuscular blocking agents. New Horiz 1994: 2: 48-55.
2. 2. Bolton CF. Sepsis and the systemic inflammatory response syndrome: neuromuscular manifestations. Crit Care Med 1996: 24: 1408-1416.
3. 3. Gutierrez G, Hurtado FJ, Fernandez E. Inhibitory effect of Escherichia coli endotoxin on skeletal muscle contractility. Crit Care Med 1995: 23: 308-315.
4. 4. Hussain SNA, Simkus G, Roussos C. Respiratory muscle fatigue: a cause of ventilatory failure in septic shock. J Appl Physiol 1985: 58: 2033-2040.
5. 5. Boczkowski J, Dureuil B, Branger C, Pavlovic D, Murciano D, Pariente R et al. Effects of sepsis on diaphragmatic function in rats. Am Rev Respir Dis 1988: 138: 260-265.
6. 6. Wilcox P, Osborne S, Bressler B. Monocyte inflammatory mediators impair in vitro hamster diaphragm contractility. Am Rev Respir Dis 1992: 146: 462-466.
7. 7. Wilcox P, Milliken C, Bressler B. High-dose tumor necrosis factor alpha produces an impairment of hamster diaphragm contractility. Am J Respir Crit Care Med 1996: 153: 1611-1615.
8. 8. Tomera JF, Martyn J. Intraperitoneal endotoxin but not protein malnutrition shifts d-tubocurarine dose-response curves in mouse gastrocnemius muscle. J Pharmacol Exp Ther 1989: 250: 216-220.
9. 9. Wichterman KA, Baue AE, Chaudry IH. Sepsis and septic shock - a review of laboratory models and a proposal. J Surg Res 1980: 29: 189-201.
10. 10. Hasselgren PO, James JH, Fischer JE. Inhibited muscle amino acid uptake in sepsis. Ann Surg 1986: 203: 360-365.
11. 11. Chen SJ, Wu CC, Yen MH. Alterations of ex vivo vascular reactivity in intraperitoneal sepsis. J Cardiovasc Pharmacol 1994: 24 : 786-793.
12. 12. Alexander HR, Doherty GM, Venzon DJ, Merino MJ, Fraker DL, Norton JA. Recombinant interleukin-1 receptor antagonist (IL-1ra): effective therapy against gram-negative sepsis in rats. Surgery 1992: 112: 188-193.
13. 13. Hussain SN, Graham R, Rutledge F, Roussos C. Respiratory muscle energetics during endotoxic shock in dogs. J Appl Physiol 1986: 60: 486-493.
14. 14. Person RJ. Endotoxin alters spontaneous transmitter release at the frog neuromuscular junction. J Neurosci Res 1977: 3: 63-72.
15. 15. Tracey KJ, Lowry SF, Beutler B, Cerami A, Albert JD, Shires GT. Cachectin/tumor necrosis factor mediates changes of skeletal muscle plasma membrane potential. J Exp Med 1986: 164: 1368-1373.