Augmentation of cAMP improves muscle-flap survival and tissue inflammation in response to ischemia/reperfusion injury

Journal of Reconstructive Microsurgery

Volumn 15, Issue 1, 1999, Pages 37-45

  Lille, Sean ^a   Boyle Jr , Edward M ^b   Schoeller, Thomas ^b   Suchy, Hans ^b   Russell, Robert C ^b  

^a Inst for Plastic/Reconstr Surg   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP;

ANIMAL TISSUE; ARTICLE; GRACILIS MUSCLE; GRAFT SURVIVAL; MALE; MUSCLE FLAP; MUSCLE ISCHEMIA; MUSCLE PERFUSION; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0032941205     PISSN: 0743684X     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-1000069     Document Type: Article

References (38)

1. Hartsock LA, Seaber AV, Urbaniak JR. Intravascular thrombosis in skeletal muscle microcirculation after ischemia. Microsurgery 1989;10:161
2. Verrier ED. The vascular endothelium: Friend or foe? Ann Thorac Surg 1993;55:818
3. Pober JS, Cotran RS. Cytokines and endothelial cell biology. Physiol Rev 1990;70:427
4. Cotran RS, Pober JS. Cytokine-endothelial interactions in inflammation, immunity, and vascular injury. J Am Soc Nephrol 1990;1:225
5. Hale SL. Role of leukocytes in reperfusion injury. In Piper HM (ed): Ischemia-Reperfusion in Cardiac Surgery. Dordrecht: Klewer Academic Publishers, 1993, pp 328-340
6. Hjortdal VE, Sinclair T, Kerrigan CL, Solymoss S. Arterial ischemia in skin flaps: Microcirculatory intravascular thrombosis Plast Reconstru Surg 1995;93:375-384
7. Vedder NB, Winn RK, Rice CL. Inhibition of leukocyte adherence by anti-CD 18 monoclonal antibody attenuates reperfusion injury in the rabbit ear. Proc Natl Acad Sc USA 1990;81:939-948
8. Lefer AM, Lefer DJ. Pharmacology of the endothelium in ischemia-reperfusion and circulatory shock. Ann Rev Pharmacol Toxicol 1993;33:71-79
9. Winn RK, Liggit D, Vedder NB, et al. ANti-P-selectin monoclonal antibody attenuates injury to the rabbit ear. J Clin Invest 1993;92:2042-2053
10. Christofidou SM, Murphy GH, Albeda SM. Induction of E-selectin-dependent leukocyte recruitment by mast cell degranulation in human skin grafts transplanted on SCID mice. Am J Pathol 1996;148:177-190
11. Orisz CG, Ohye RG, Pelletier RP. Treatment with anti-vascular adhesion molecule-1 monoclonal antibody induces long-term murine cardiac allograft acceptance. Transplantation 1993;56:45-53
12. Simpson PJ, Todd RF, Fantone JC. Reduction of experimental canine myocardial reperfusion injury by a monoclonal antibody (anti-Mol, anti-CD11b) that inhibits leukocyte adhesion. J Clin Invest 1988;81:624-634
13. Simpson PJ, Todd RF, Mickelson JK. Sustained limitation of myocardial reperfusion injury by a monoclonal antibody that alters leukocyte function. Circulation 1990;81:226-232
14. Ma XL, Weyrich AS, Lefer DJ. Monoclonal antibody to L-selectin attenuates neutrophil accumulation and protects ischemic reperfused cat myocardium. Circulation 1993;88: 649-658
15. Ma XL, Lefer DJ, Lefer AM, Rothlein R. Coronary endothelial and cardiac protective effects of a monoclonal antibody to intercellular adhesion molecule-1 in myocardial ischemia and reperfusion. Circulation 1992;86:937
16. Karin M. Signal transduction from cell surface to nucleus in development and disease FASEB J 1992;8:2581-2590
17. Magnuson DK, Maier RV, Pohlman TH. Protein kinase C: A potential pathway of endothelial activation by endotoxin, tumor necrosis factor, and interleukin-1. Surgery 1989;106: 216-223
18. Collins T, Read MA, Neisch AS. Transcriptional regulation of endothelial cell adhesion molecules: NF-kB and cytokine-inducible enhancers. FASEB J 1995;9:899-909
19. Thanos D, Maniatis T. NF-kB: A lesson in family values. Cell 1995;80:529-532
20. Ghersa PR, Hooft van Huijsduijnen R, Whelan J, et al. Inhibition of E-selectin gene transcription through a cAMP-dependent protein kinase pathway. J Biol Chem 1994;269: 29129
21. Pober JS, Slowik MR, Deluca LG, Ritchie AJ. Elevated cAMP inhibits endothelial cell synthesis and expression of TNF-induced endothelial leukocyte adhesion molecule-1. and vascular cell adhesion molecule-1, but not intercellular adhesion molecule-1. J Immunol 1993;150:5114-5120
22. Morandini R, Ghanem G, Portier-Lemarie A, et al. Action of cAMP on expression and release of adhesion molecules in human endothelial cells. Am J Physiol 1996;270:H807
23. Stelzner TJ, Weil JV, O'Brien RF. Role of cyclic adenosine monophosphate in the induction of endothelial properties. J Cell Physiol. 1989;139:157-167
24. Pinsky D, Oz M, Lioao H, et al. Restoration of the cAMP second messenger pathway enhances cardiac preservation for transplantation in a heterotopic rat model. J Appl Physiol 1993; 92:2994-3004
25. Harlan J. Leukocyte-endothelial interactions. Blood 1985;65: 513-525
26. Labbe R, Lindsay T, Gatley R, et al. Quantitation of postischemic skeletal muscle necrosis: Histochemical and radioisotope techniques. J Surg Res 1988;44:45
27. Adkins WK, Barnard JW, May S, et al. Compounds that increase cAMP prevent ischemia-reperfusion pulmonary capillary injury. J Appl Physiol 1992;72:492-503
28. Barnard JW, Seibert AF, Prasad VR, et al. Reversal of pulmonary capillary ischemia-reperfusion injury by rolipram, a cAMP phosphodiesterase inhibitor. J Appl Physiol 1994; 77:774-789
29. Ogawa S, Koga S, Kuwabura K. Hypoxia-induced increased permeability of endothelial monolayers occurs through lowering cAMP levels. Am J Physiol 1994;262:C546
30. Zund G, Nelson DP, Nueffeld EJ, et al. Hypoxia enhances stimulus-dependent induction of E-selectin on aortic endothelial cells. Proc Natl Acad Sci USA 1996;93:7075-7084
31. Fries JW, Williams AJ, Atkins RC, et al. Expression of VCAM-1 and E-selectin in an in vivo model of endothelial activation. Am J Pathol 1993;143:725
32. Derian CK, Santulli RJ, Rao PE, et al. Inhibition of chemotactic peptide-induced neutrophil adhesion to vascular endothelium by cAMP modulators. J Immunol 1995;154: 308-318
33. Nielson CP. B-adrenergic modulation of the polymorphonuclear leukocyte respiratory burst is dependent upon the mechanism of cell activation. J Immunol 1987;139:2392-2340
34. Elices MJ, Osborn L, Takada Y, et al. VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4, a site distinct from the VLA-fibronectin binding site. Circulation 1990;60:577-590
35. Ogawa S, Gerlach H, Esposito C, et al. Hypoxia modulates the barrier and coagulant function of cultured bovine endothelium. J Clin Invest 1990;85:1090-1099
36. Lamb NC, Fernandez A, Conti MA, et al. Regulation of actin microfilament integrity in living non-muscle cells by the cAMP-dependent protein kinase and the myosine light chain kinase. J Cell Biol 1988;106:1955-2005
37. Zamboni WA. Microarteriole vasoconstriction reduces functional blood flow to ischemic skeletal muscle during reperfusion. Surg Forum 1995;46:725-735
38. Boese M, Busse R, Mulsch A, Schini-Kerth V. Effect of cGMP-dependent vasodilators on the expression of inducible nitric oxide synthase in vascular smooth muscle cells: Role of cAMP. Brit J Pharm 1996;119:707