Changes in sensitivity of a human myeloid cell line (U937) to metal toxicity after glutathione depletion

Immunopharmacology and Immunotoxicology

Volumn 21, Issue 2, 1999, Pages 277-293

  Danfour, M ^a   Schorah, C J ^a   Evans, S W ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; CADMIUM; COBALT; GLUTATHIONE; GOLD; MERCURY; ZINC;

ARTICLE; BONE MARROW CULTURE; CELL CULTURE; CELL CYCLE; CELL VIABILITY; CHEMOSENSITIVITY; CYTOTOXICITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

EID: 0032940499     PISSN: 08923973     EISSN: None     Source Type: Journal    
DOI: 10.3109/08923979909052763     Document Type: Article

References (20)

1. Meister, A., Glutathione metabolism and its selective modification, Journal of Biological Chemistry, 263:17205, 1988.
2. Chung, A. S. and Maines, M. D., Differential effect of cadmium on GSH-peroxidase activity in the Leydig and the Sertoli cells of rat testis. Suppression by selenium and the possible relationship to heme concentration, Biochemical Pharmacology, 36:1367, 1987.
3. Jornot, L. and Junod, A. F., Variable glutathione levels and expression of antioxidant enzymes in human endothelial cells, American Journal of Physiology, 264:L482, 1993.
4. Ballatori, N., Glutathione mercaptides as transport forms of metals. Advances in Pharmacology, 27:271, 1994.
5. Singhal, R. K., Anderson, M. E. and Meister, A., Glutathione, a first line of defense against cadmium toxicity, FASEB Journal, 1:220, 1987.
6. Suzuki, C. A. and Cherian, M. G., Renal glutathione depletion and nephrotoxicity of cadmium-metallothionein in rats, Toxicology & Applied Pharmacology, 98:544, 1989.
7. Naganuma, A., Anderson, M. E. and Meister, A., Cellular glutathione as a determinant of sensitivity to mercuric chloride toxicity. Prevention of toxicity by giving glutathione monoester, Biochemical Pharmacology, 40:693, 1990.
8. Sundstrom, C. and Nilsson, K., Establishment and characterization of a human histiocytic lymphoma cell line (U-937), International Journal of Cancer, 17:565, 1976.
9. Koren, H. S., Anderson, S. J. and Larrick, J. W., In vitro activation of a human macrophage-like cell line, Nature, 279:328, 1979.
10. Hedley, D. W. and Chow, S., Evaluation of methods for measuring cellular glutathione content using flow cytometry, Cytometry, 15:349, 1994.
11. Graham, A., Wood, J. L., VJ, O. L. and Stone, D., Human (THP-1) macrophages oxidize LDL by a thiol-dependent mechanism, Free Radical Research, 21:295, 1994.
12. Mihm, S., Ennen, J., Pessara, U., Kurth, R. and Droge, W., Inhibition of HIV-1 replication and NF-kappa B activity by cysteine and cysteine derivatives, Aids, 5:497, 1991.
13. Mokrasch, L. C. and Teschke, E. J., Glutathione content of cultured cells and rodent brain regions: a specific fluorometric assay, Analytical Biochemistry, 140:506, 1984.
14. Keogh, J. P., Steffen, B. and Siegers, C. P., Cytotoxicity of heavy metals in the human small intestinal epithelial cell line I-407: the role of glutathione, Journal of Toxicology & Environmental Health, 43:351, 1994.
15. Ochi, T., Otsuka, F., Takahashi, K. and Ohsawa, M., Glutathione and metallothioneins as cellular defense against cadmium toxicity in cultured Chinese hamster cells, Chemico-Biological Interactions, 65:1, 1988.
16. Freedman, J. H., Ciriolo, M. R. and Peisach, J., The role of glutathione in copper metabolism and toxicity, Journal of Biological Chemistry, 264:5598, 1989.
17. Shaw, C. F. d., Isab, A. A., Coffer, M. T. and Mirabelli, C. K., Gold(I) efflux from auranofin-treated red blood cells. Evidence for a glutathione-gold-albumin metabolite, Biochemical Pharmacology, 40:1227, 1990.
18. Goebel, C., Kubicka-Muranyi, M., Tonn, T., Gonzalez, J. and Gleichmann, E., Phagocytes render chemicals immunogenic: oxidation of gold(I) to the T cell-sensitizing gold(III) metabolite generated by mononuclear phagocytes, Archives of Toxicology, 69:450, 1995.
19. Ochi, T., Takahashi, K. and Ohsawa, M., Indirect evidence for the induction of a prooxidant state by cadmium chloride in cultured mammalian cells and a possible mechanism for the induction, Mutation Research, 180:257, 1987.
20. Saito, S. and Kojima, Y., Relative gold-binding capacity of metallothionein: studies in renal cytosols of gold-injected rats, Research Communications in Molecular Pathology & Pharmacology, 92:119, 1996.