Increased density of jejunal γδ+ T cells in patients having normal mucosa - Marker of operative autoimmune mechanisms?

Autoimmunity

Volumn 29, Issue 3, 1999, Pages 179-187

  Iltanen, Sari ^d   Holm, Kati ^d   Partanen, Jukka ^a   Laippala, Pekka ^b   Mäki, Markku ^c  

^a Finnish Red Cross   (Finland)

^b TAMPERE UNIVERSITY HOSPITAL   (Finland)

^c UNIVERSITY OF TAMPERE   (Finland)

^d NONE

Author keywords

Autoimmune; Coeliac disease; HLA DQ2; Reticulin antibodies; T cells

Indexed keywords

AUTOANTIBODY; GLIADIN ANTIBODY; HLA DQ ANTIGEN; HLA DR ANTIGEN; IMMUNOGLOBULIN A; MONOCLONAL ANTIBODY; RETICULIN; T LYMPHOCYTE RECEPTOR DELTA CHAIN; T LYMPHOCYTE RECEPTOR GAMMA CHAIN;

ADOLESCENT; ARTICLE; AUTOIMMUNITY; CELIAC DISEASE; CHILD; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; INFANT; JEJUNUM MUCOSA; MAJOR CLINICAL STUDY; PRESCHOOL CHILD; SCHOOL CHILD; T LYMPHOCYTE;

EID: 0032939962     PISSN: 08916934     EISSN: None     Source Type: Journal    
DOI: 10.3109/08916939908998533     Document Type: Article

References (33)

1. Mäki, M. and Collin, P. Coeliac disease. Lancet 1997; 349: 1755-1759.
2. Sollid, L.M. and Thorsby, E. HLA susceptibility genes in celiac disease: genetic mapping and role in pathogenesis. Gastroenterol 1993; 105: 910-922.
3. Collin, P. and Mäki, M. Associated disorders in coeliac disease: clinical aspects. Scand. J. Gastroenterol. 1994; 29: 769-775.
4. Ferguson, A., Arranz, E. and O'Mahony, S. Clinical and pathological spectrum of coeliac disease - active, silent, latent, potential. Gut 1993; 34: 150-151.
5. Marsh, M.N. and Crowe, P.T. Morphology of the mucosal lesion in gluten sensitivity. Bailliere's Clin. Gastroenterol. 1995; 9: 273-293.
6. Halstensen, T.S., Scott, H. and Brandtzaeg, P. Intraepithelial T cells of the TcR gamma/delta + CD8- and V delta 1/J delta 1 + phenotypes are increased in coeliac disease. Scand. J. Immunol. 1989; 30: 665-672.
7. Savilahti, E., Arato, A. and Verkasalo, M. Intestinal gamma delta receptor-bearing T lymphocytes in celiac disease and inflammatory bowel diseases in children. Constant increase in celiac disease. Pediair. Res. 1990; 28: 579-581.
8. Holm, K., Mäki, M., Savilahti, E., Lipsanen, V., Laippala, P. and Koskimies, S. Intraepithelial gamma/delta T-cell-receptor lymphocytes and genetic susceptibility to coeliac disease. Lancet 1992; 339: 1500-1503.
9. Mäki, M., Holm, K., Collin, P. and Savilahti, E. Increase in gamma delta T cell receptor bearing lymphocytes in normal small bowel mucosa in latent coeliac disease. Gut 1991; 32: 1412-1414.
10. Kabelitz, D. Function and specificity of human gamma/ delta-positive T cells. Crit. Rev. Immunol. 1992; 11: 281-303.
11. Sciammas, R., Tatsumi, Y., Sperling, M., Arunan, K. and Bluestone, J. A. TCR gamma delta cells: mysterious cells of the immune cells. Immunol. Res. 1994; 13: 268-279.
12. Mäki, M. The humoral immune system in coeliac disease. Baillieres Clin. Gastroenterol. 1995; 9: 231-249.
13. Dieterich, W., Ehnis, T., Bauer, M., Donner, P., Volta, U., Riecken, E.O. and Schuppan, D. Identification of tissue transglutaminase as the autoantigen of celiac disease. Mature. Med. 1997; 3: 797-801.
14. Picarelli, A., Maiuri, L., Frate, A., Greco, M., Auricchio, S. and Londel, M. Production of antiendomysial antibodies after in-vitro gliadin challenge of small intestine biopsy samples from patients with coeliac disease. Lancet 1996; 348: 1065-1067.
15. Lanzavecchia, A. How can cryptic epitopes trigger autoimmunity? J. Exp. Med. 1995; 181: 1945-1948.
16. Walker-Smith, J. A., Guandalini, S., Schmitz, J., Shmerling, D.H. and Visakorpi, J.K. Revised criteria for diagnosis of coeliac disease. Arch. Dis. Child 1990; 65: 909-911.
17. Mäki, M., Lähdeaho, M.L., Hällström, O., Viander M and Visakorpi, J.K. Postpubertal gluten challenge in coeliac disease. Arch. Dis. Child 1989; 64: 1604-1607.
18. Spencer, J., Isaacson, P.G., MacDonald, T.T., Thomas, A.J. and Walker-Smith, J.A. Gamma/delta T cells and the diagnosis of coeliac disease. Clin. Exp. Immunol. 1991; 85: 109-113.
19. Mäki, M., Hällström, O., Vesikari, T. and Visakorpi, J.K. Evaluation of a serum IgA-class reticulin antibody test for the detection of childhood celiac disease. J. Pediatr. 1984; 105: 901-905.
20. Savilahti, E., Viander, M., Perkkio, M., Vainio, E., Kalimo, K. and Reunala, T. IgA antigliadin antibodies: a marker of mucosal damage in childhood coeliac disease. Lancet 1983; 1: 320-322.
21. Ota, M., Seki, T., Nomura, N., Sugimura, K., Mizuki, N., Fukushima, H. et al. Modified PCR-RFLP method for HLA-DPB1 and -DQA1 genotyping. Tissue Antigens 1991; 39: 60-71.
22. Kimura, A. and Sasazuki, T. Eleventh international histocompatibility workshop reference protocol for the HLA DNA-typing technique. In: Sasazuki T. Ed. HLA 1991. Oxford: Oxford University Press, 1992.
23. Wright, D.K. and Manos, M.M. Sample preparation from paraffin-embedded tissues. In: Ennis, M.A. Ed. PCR protocols. A Guide to Methods and Applications. San Diego: Academic Press, 1990.
24. Polvi, A., Eland, C., Koskimies, S., Mäki, M. and Partanen, J. HLA DQ and DP in Finnish families with celiac disease. Eur. J. Immunogen. 1996; 23: 221-234.
25. Boismenu, R. and Havran, L. Modulation of epithelial growth by intraepithelial gamma/delta T cells. Science 1994; 266: 1253-1255.
26. Li, H., Lebedeva, M.I., Liera, A.S., Fields, B.A., Brenner, M.B. and Mariuzza, R.A. Structure of the Vδ domain of a human γδ T-cell antigen receptor. Nature 1998; 391: 502-506.
27. Hayday, A.C., Roberts, S. and Smith, A.L. γδ cells in coeliac disease. In: Mäki, M., Collin, P., Visakorpi, J.K. Ed. Coeliac Disease. Tampere: University of Tampere 1997: 311-320.
28. Mäki, M., Holm, K., Koskimies, S., Hällström, O. and Visakorpi, J.K. Normal small bowel biopsy followed by coeliac disease. Arch. Dis. Child 1990; 65: 1137-1141.
29. Troncone, R. Latent coeliac disease in Italy. Acta. Paediatr. 1995; 84: 1252-1257.
30. Collin, P., Helin, H., Mäki, M., Hällström, O. and Karvonen. A-L. Follow-up of patients positive in reticulin and gliadin antibody tests with normal small bowel biopsy findings. Scand. J. Gastroenterol. 1993; 28: 595-598.
31. Picarelli, A., Maiuri, L., Mazzilli, M.C., Coletta, S., Ferrante, P., Giovambattista, F.D., Greco, M., Torsoli, A. and Auricchio, S. Gluten-sensitive diseases with mild enteropathy. Gastroenterol. 1996; 111: 608-616.
32. Mäki, M., Huupponen, T., Holm, K. and Hällström, O. Seroconversion of reticulin autoantibodies predicts coeliac disease in insulin dependent diabetes mellitus. Gut 1995; 36: 239-242.
33. Savilahti, E., Reunala, T. and Mäki, M. Increase of lymphocytes bearing the gamma/delta T cell receptor in the jejunum of patients with dermatitis herpetiformis. Gut 1992; 33: 206-211.