Syntheses and analgesic activities of some 2-substituted-4,5-diphenyl and 1,2-disubstituted-4,5-diphenyl imidazole derivatives

Bollettino Chimico Farmaceutico

Volumn 138, Issue 1, 1999, Pages 24-29

  Isikdag I ^a   Meric A ^a  

^a ANADOLU UNIVERSITY   (Turkey)

Author keywords

Analgesic activity; Imidazoles

Indexed keywords

2 (4 CHLOROPHENYL) 4,5 DIPHENYLIMIDAZOLE; 2 (4 HYDROXYPHENYL) 4,5 DIPHENYLIMIDAZOLE; ALDEHYDE DERIVATIVE; AMMONIUM ACETATE; HALIDE; IMIDAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANALGESIA; ANIMAL MODEL; ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; DRUG EFFICACY; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; INFRARED SPECTROPHOTOMETRY; LETHAL DOSE; MALE; MOUSE; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; PURIFICATION;

ANALGESICS, NON-NARCOTIC; ANIMALS; IMIDAZOLES; MAGNETIC RESONANCE SPECTROSCOPY; MICE; PAIN MEASUREMENT; RATS; SPECTROPHOTOMETRY, INFRARED; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 0032939596     PISSN: 00066648     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. CIBA Ltd., Neth. Appl. 6, 412, 310, April 26 (1965) ref. C.A. 63: 11573c-d (1965).
2. J.G. Lombardino, Ger. Offen. 2, 155, 558, 29 Jun (1972) ref. C.A. 77: 101607y (1972).
3. J.G. Lombardino, E.H. Wiseman, J. Med. Chem., 17(11), 1182 (1974).
4. H. Bredereck, R. Gompper, D. Hayer, Chem. Ber., 92, 338 (1959).
5. R. Quelet, E. Frainnet, Compt. rend., 236, 492 (1953) ref. C.A. 48: 1244b (1954).
6. R. Quelet, E. Frainnet, Compt. rend., 236, 492 (1953) ref. C.A. 48: 1244b (1954).
7. B. Bottcher, F. Bauer, Chem. Ber., 84, 289 (1951).
8. A.H. Cook, D.G. Jones, J. Chem. Soc., 278 (1941).
9. C.V. Deliwala, S. Rajagopalan, Proc. Indian Acad. Sci., 31A, 107 (1950) ref. CA. 44: 7440b (1950).
10. C.V. Deliwala, S. Rajagopalan, Proc. Indian Acad. Sci., 31A, 107 (1950) ref. CA. 44: 7440b (1950).
11. E.I. du Pont de Nemours & Co., Belg. 635, 804. Dec. 2 (1963) ref. C.A. 63:1795d (1965).
12. G.E. Philbrook, M.A. Maxwell, R.E. Taylor, J.R. Totter, Photochem. Photobiol., 4 (6), 1175 (1965) ref. C.A. 64: 15869b (1966).
13. G.E. Philbrook, M.A. Maxwell, R.E. Taylor, J.R. Totter, Photochem. Photobiol., 4 (6), 1175 (1965) ref. C.A. 64: 15869b (1966).
14. A.G. Kalle, Ger. 1, 106, 599, Apr 9 (1959) ref. C.A. 56: 3065f (1962).
15. B. Radziszewski, Anz. Akad. wiss. Krakau, 213 (1909), through Chem. Zentr., I, 1883 (1909) ref. C.A. 4: 2266-2265 (1909).
16. B. Radziszewski, Anz. Akad. wiss. Krakau, 213 (1909), through Chem. Zentr., I, 1883 (1909) ref. C.A. 4: 2266-2265 (1909).
17. B. Radziszewski, Anz. Akad. wiss. Krakau, 213 (1909), through Chem. Zentr., I, 1883 (1909) ref. C.A. 4: 2265-2266 (1909).
18. H. Schubert, E. Hagen, G. Lehmann, J. Prakt. Chem., 17, 173 (1962) ref. C.A. 58: 1329h (1963).
19. H. Schubert, E. Hagen, G. Lehmann, J. Prakt. Chem., 17, 173 (1962) ref. C.A. 58: 1329h (1963).
20. İ. Işikdaǧ, Ü. Uçucu, B. Çakir, Gazi Üniv. Eczacilik Fak. Derg., 6(1), 49 (1989) ref. C.A. 112: 118717y (1990).
21. İ. Işikdaǧ, Ü. Uçucu, B. Çakir, Gazi Üniv. Eczacilik Fak. Derg., 6(1), 49 (1989) ref. C.A. 112: 118717y (1990).
22. İ. Işikdaǧ, Ü. Uçucu, Acta Pharm. Turc., 36(4), 102 (1994).
23. A.M. Simonov, A.D. Garnovskii, Zhur. Obshchei Khim., 31, 114 (1961) ref. C.A. 55: 22298f (1961).
24. A.M. Simonov, A.D. Garnovskii, Zhur. Obshchei Khim., 31, 114 (1961) ref. C.A. 55: 22298f (1961).
25. W. Klose, I. Boettcher, Ger. Offen., 3, 141, 63, 28 Apr (1983) ref. C.A. 99: 88196w (1983).
26. E.F. Silversmith, J. Org. Chem. 28(12), 3568 (1963).
27. D. Lorke, Arch. Toxicol., 54, 275 (1983).
28. F.E. D'Amour, D.L. Smith, J. Pharmacol. Exp. Ther., 72, 74 (1941).
29. M. Kunihara, M. Ohyama, M. Nakano, Eur. J. Pharmacol., 214, 111 (1992).