Whipple's arthritis: Direct detection of Tropheryma whippelii in synovial fluid and tissue

Arthritis and Rheumatism

Volumn 42, Issue 4, 1999, Pages 812-817

  O'Duffy, J Desmond ^a   Griffing, W Leroy ^a   Li, Chin Yang ^a   Abdelmalek, Manal F ^a   Persing, David H ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; COTRIMOXAZOLE; MINOCYCLINE; RNA 16S;

ADULT; ANTIBIOTIC THERAPY; ARTICLE; CASE REPORT; GENE SEQUENCE; HISTOPATHOLOGY; HUMAN; INTESTINE LIPODYSTROPHY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SYNOVIAL FLUID; SYNOVITIS; SYNOVIUM; TROPHERYMA WHIPPELII;

ACTINOBACTERIA; ADULT; ARTHRITIS, REACTIVE; DNA, BACTERIAL; HUMANS; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; RNA, BACTERIAL; RNA, RIBOSOMAL, 16S; SYNOVIAL FLUID; SYNOVIAL MEMBRANE; WHIPPLE DISEASE;

EID: 0032939235     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/1529-0131(199904)42:4<812::AID-ANR27>3.0.CO;2-S     Document Type: Article

References (15)

1. Fleming JL, Wiesner RH, Shorter RG. Whipple's disease: clinical, biochemical, and histopathologic features and assessment of treatment in 29 patients. Mayo Clin Proc 1988;63:539-51.
2. Feuerle GE, Marth T. An evaluation of antimicrobial treatment for Whipple's disease: tetracycline versus trimethoprimsulfamethoxazole. Dig Dis Sci 1994;39:1642-8.
3. Dobbins WO III. Whipple's disease. Springfield (IL): Charles C. Thomas; 1987.
4. Ramzan NN, Loftus E Jr, Burgart LJ, Rooney M, Baits KP, Wiesner RH, et al. Diagnosis and monitoring of Whipple disease by polymerase chain reaction. Ann Intern Med 1997;126:520-7.
5. Keinath RD, Merrell DE, Vlietstra R, Dobbins WO III. Antibiotic treatment and relapse in Whipple's disease. Gastroenterology 1985;88:1867-73.
6. Relman DA, Schmidt TM, MacDermott RP, Falkow S. Identification of the uncultured bacillus of Whipple's disease. N Engl J Med 1992;327:293-301.
7. Rickman LS, Freeman WR, Green WR, Feldman ST, Sullivan J, Russack V, et al. Brief report: uveitis caused by Tropheryma whippelii (Whipple's bacillus). N Engl J Med 1995;332:363-6.
8. Maizel H, Ruffin JM, Dobbins WO III. Whipple's disease: a review of 19 patients from one hospital and a review of the literature since 1950. Medicine (Baltimore) 1970;49:175-205.
9. Whipple GH. A hitherto undescribed disease characterized anatomically by deposits of fat and fatty acids in the intestinal and mesenteric lymphatic tissues. Johns Hopkins Hosp Bull 1907;198: 382-91.
10. Schilling D, Adamek HE, Kaufmann V, Maier M, Riemann JF. Arthralgia as an early extraintestinal symptom of Whipple's disease. J Clin Gastroenterol 1997;24:18-20.
11. Rubinow A, Canoso JJ, Goldenberg DL, Cohen AS, Shirahama T. Arthritis in Whipple's disease. Isr J Med Sci 1981;17:445-9.
12. Nocton JJ, Dressler F, Rutledge BJ, Rys PN, Persing DH, Steere AC. Detection of Borrelia burgdorferi DNA by polymerase chain reaction in synovial fluid from patients with Lyme arthritis. N Engl J Med 1994;330:229-34.
13. Rahman MU, Cheema MA, Schumacher HR, Hudson AP. Molecular evidence for the presence of Chlamydia in the synovium of patients with Reiter's syndrome. Arthritis Rheum 1992;35:521-9.
14. Lowsky R, Archer GL, Fyles G, Minden M, Curtis J, Messner H, et al. Brief report: diagnosis of Whipple's disease by molecular analysis of peripheral blood. N Engl J Med 1994;331:1343-6.
15. Marth T, Fredricks D, Strober W, Relman DA. Limited role for PCR-based diagnosis of Whipple's disease from peripheral blood mononuclear cells. Lancet 1996;348:66-7.