Regulation of excision of the conjugative transposon Tn916

Molecular Microbiology

Volumn 31, Issue 2, 1999, Pages 609-621

  Marra, Diana ^a   Scott, June R ^a  

^a EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA;

ARTICLE; BACTERIUM CONJUGATION; DNA REPAIR; DNA TRANSCRIPTION; EXCISION REPAIR; GENE EXPRESSION REGULATION; GRAM POSITIVE BACTERIUM; NONHUMAN; PRIORITY JOURNAL; TRANSPOSON;

BACILLUS SUBTILIS; BASE SEQUENCE; BINDING SITES; CONJUGATION, GENETIC; DNA NUCLEOTIDYLTRANSFERASES; DNA REPAIR; DNA, CIRCULAR; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, BACTERIAL; INTEGRASES; MOLECULAR SEQUENCE DATA; MUTAGENESIS; OPEN READING FRAMES; PROMOTER REGIONS (GENETICS); RECOMBINASES; TRANSPOSASES; VIRAL PROTEINS;

EID: 0032938505     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.1999.01201.x     Document Type: Article

References (46)

1. Bushman, W., Yin, S., Thio, L.L., and Landy, A. (1984) Determinants of directionality in lambda site-specific recombination. Cell 39: 699-706.
2. Caparon, M.G., and Scott, J.R. (1989) Excision and insertion of the conjugative transposon Tn916 involves a novel recombination mechanism. Cell 59: 1027-1034.
3. Celli, J., and Trieu-Cuot, P. (1998) Circularization of Tn916 is required for expression of the transposon-encoded transfer functions: characterization of long tetracycline-inducible transcripts reading through the attachment site. Mol Microbiol 28: 103-117.
4. Clewell, D.B., Flannagan, S.E., and Jaworski, D.D. (1995) Unconstrained bacterial promiscuity: the Tn916-Jn 1545 family of conjugative transposons. Trends Microbiol 3: 229-236.
5. Courvalin, P., and Carlier, C. (1986) Transposable multiple antibiotic resistance in Streptococcus pneumoniae. Mol Gen Genet 205: 291-297.
6. Craig, N.L. (1991) Tn7: a target site-specific transposon. Mol Microbiol 5: 2569-2573.
7. Echols, H., and Guarneros, G. (1983) Control of integration and excision. In Lambda II. Hendrix, R.W., Roberts, J.W., Stahl, F.W., and Weisberg, R.A. (eds). Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, pp. 75-92.
8. Eichenbaum, Z., Federle, M.J., Marra, D., de Vos, W.M., Kuipers, O.P., Kleerebezem, M., and Scott, J.R. (1998) Use of the lactococcal nisA promoter to regulate gene expression in Gram-positive bacteria: comparison of induction level and promoter strength. Appl Environ Microbiol 64: 2763-2769.
9. Evans, R.P., and Macrina, F.L. (1983) Streptococcal plasmid plP501: endonuclease site map, resistance determinant location, and construction of novel derivatives. J Bacteriol 154: 1347-1355.
10. Fischetti, V.A., Jones, K.F., and Scott, J.R. (1985) Size variation of the M protein in group A streptococci. J Exp Med 161: 1384-1401.
11. Franke, A.E., and Clewell, D.B. (1981) Evidence for a chromosome-borne resistance transposon (Tn916) in Streptococcus faecalis that is capable of conjugative transfer in the absence of a conjugative plasmid. J Bacteriol 145: 494-502.
12. Froehlich, B., Husmann, L., Caron, J., and Scott, J.R. (1994) Regulation of rns, a positive regulatory factor for pili of enterotoxigenic Escherichia coli. J Bacteriol 176: 5385-5392.
13. Gartner, D., Degenkolb, J., Ripperger, J.A.E., Allmansberger, R., and Hillen, W. (1992) Regulation of the Bacillus subtilis W23 xylose utilization operon: interaction of the Xyl repressor with the xyl operator and the inducer xylose. Mol Gen Genet 232: 415-422.
14. Harwood, C.R., and Cutting, S.M. (1990) Molecular Biological Methods for Bacillus. London: John Wiley & Sons, p. 40.
15. Heimann, J.D. (1995) Compilation and analysis of Bacillus subtilis sigma A-dependent promoter sequences: evidence for extended contact between RNA polymerase and upstream promoter DNA. Nucleic Acids Res 23: 2351-2360.
16. Horaud, T., de Cespedes, G., Clermont, D., David, F., and Delbos, F. (1991) Variability of chromosomal genetic elements in streptococci. In Genetics and Molecular Biology of Streptococci, Lactococci, and Enterococci. Dunny, G.M., Cleary, P.P., and McKay, L.L. (eds). Washington DC: American Society for Microbiology Press, pp. 16-20.
17. Ionesco, H., Michel, J., Cami, B., and Schaeffer, P. (1970) Symposium on bacterial spores. II. Genetics of sporulation in Bacillus subtilis Marburg. J Appl Bacteriol 33: 13-24.
18. Jaworski, D.D., and Clewell, D.B. (1994) Evidence that coupling sequences play a frequency-determining role in conjugative transposition of Tn916 in Enterococcus faecalis. J Bacteriol 176: 3328-3335.
19. Jaworski, D.D., Flannagan, S.E., and Clewell, D.B. (1996) Analyses of traA, int-Tn, and xis-Tn mutations in the conjugative transposon Tn916 in Enterococcus faecalis. Plasmid 36: 201-208.
20. Leffers, G.G., and Gottesman, S. (1998) Lambda Xis degradation in vivo by Lon and FtsH. J Bacteriol 180: 1573-1577.
21. Lerner, C.G., Stephenson, B.T., and Switzer, R.L. (1987) Structure of the Bacillus subtilis pyrimidine biosynthetic (pyr) gene. J Bacteriol 169: 2202-2206.
22. Lu, F., and Churchward, G. (1995) Tn916 target DNA sequences bind the C-terminal domain of integrase protein with different affinities that correlate with transposon insertion frequency. J Bacteriol 177: 1938-1946.
23. Manganelli, R., Ricci, S., and Pozzi, G. (1996) Conjugative transposon Tn916: evidence for excision with formation of 5'-protruding termini. J Bacteriol 178: 5813-5816.
24. Manganelli, R., Ricci, S., and Pozzi, G. (1997) The joint of Tn916 circular intermediates is a homoduplex in Enterococcus faecalis. Plasmid 38: 71-78.
25. Menard, R., Sansonetti, P.J., and Parsot, C. (1993) Nonpolar mutagenesis of the ipa genes defines IpaB, IpaC, and IpaD as effectors of Shigella flexneri entry into epithelial cells. J Bacteriol 175: 5899-5906.
26. Moitoso de Vargas, L., and Landy, A. (1991) A switch in the formation of alternative DNA loops modulates lambda site-specific recombination. Proc Natl Acad Sci USA 88: 588-592.
27. Numrych, T.E., Gumport, R.I., and Gardner, J.F. (1992) Characterization of the bacteriophage lambda excisionase (Xis) protein: the C-terminus is required for Xis-integrase cooperatively but not for DNA binding. EMBO J 11: 3797-3806.
28. Nunes-Duby, S.E., Matsumoto, L., and Landy, A. (1987) Site-specific recombination intermediates trapped with suicide substrates. Cell 50: 779-788.
29. Nunes-Duby, S.E., Hyock, J.K., Radhakrishna, S.T., Ellenberger, T., and Landy, A. (1998) Similarities and differences among 105 members of the Int family of site-specific recombinases. Nucleic Acids Res 26: 391-406.
30. Okada, N., Geist, R.T., and Caparon, M.G. (1993) Positive transcriptional control of mry regulates virulence in the group A streptococcus. Mol Microbiol 7: 893-903.
31. Perez-Casal, J., Swartley, J.S., and Scott, J.R. (1990) Gene encoding the major subunit of CS1 pili of human enterotoxigenic Escherichia coli. Infect Immun 58: 3594-3600.
32. Poyart-Salmeron, C., Trieu-Cuot, P., Carlier, C., and Courvalin, P. (1989) Molecular characterization of two proteins involved in the excision of the conjugative transposon Tn 1545: homologies with other site-specific recombinases. EMBO J 8: 2425-2433.
33. Poyart-Salmeron, C., Trieu-Cuot, P., Carlier, C., and Courvalin, P. (1990) The integration-excision system of the conjugative transposon Tn1545 is structurally and functionally related to those of the lambdoid phages. Mol Microbiol 4: 1513-1521.
34. Rudy, C.K., and Scott, J.R. (1996) Length of coupling sequence of Tn916. J Bacteriol 176: 3386-3388.
35. Rudy, C., Taylor, K.L., Hinerfield, D., Scott, J.R., and Churchward, G. (1997a) Excision of a conjugative transposon in vitro by the Int and Xis proteins of Tn916. Nucleic Acids Res 25: 4061-4066.
36. Rudy, C.K., Scott, J.R., and Churchward, G. (1997b) DNA binding by the Xis protein of the conjugative transposon Tn916. J Bacteriol 179: 2567-2572.
37. Scott, J.R. (1972) A new gene controlling lysogeny in phage P1. Virology 48: 282-283.
38. Scott, J.R., and Churchward, G.G. (1995) Conjugative transposition. Annu Rev Microbiol 49: 367-397.
39. Scott, J.R., Kirchman, P.A., and Caparon, M.G. (1988) An intermediate in the transposition of the conjugative transposon Tn916. Proc Natl Acad Sci USA 85: 4809-4813.
40. Scott, J.R., Bringel, F., Marra, D., Van Alstine, G., and Rudy, C.K. (1994) Conjugative transposition of Tn916: preferred targets and evidence for conjugative transfer of a single strand and for a double-stranded circular intermediate. Mol Microbiol 11: 1099-1108.
41. Short, J.M., Fernandez, J.M., Sorge, J.A., and Huse, W.D. (1988) Lambda ZAP: a bacteriophage lambda expression vector with in vivo excision properties. Nucleic Acids Res 16: 7583-7600.
42. Storrs, M.J., Poyart-Salmeron, C., Trieu-Cuot, P., and Courvalin, P. (1991) Conjugative transposition of Tn916 requires the excisive and integrative activities of the transposon-encoded integrase. J Bacteriol 173: 4347-4352.
43. Su, Y.A., and Clewell, D.B. (1993) Characterization of the left 4 kb of conjugative transposon Tn916: determinants involved in excision. Plasmid 30: 234-250.
44. Taylor, K.L., and Churchward, G.G. (1997) Specific DNA cleavage mediated by the integrase of conjugative transposon Tn916. J Bacteriol 79: 1117-1125.
45. de Vos, W.M., and Simons, G.F.M. (1994) Gene cloning and expression systems in lactococci. In Genetics and Biotechnology of Lactic Acid Bacteria. Gasson, M.J., and de Vos, W.M. (eds). New York: Routledge, Chapman & Hall, pp. 52-105.
46. Yanisch-Perron, C., Vieira, J., and Messing, J. (1985) Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors. Gene 33: 103-119.