Previously undetected Chlamydia trachomatis infection, immunity to heat shock proteins and tubal occlusion in women undergoing in-vitro fertilization

Human Reproduction

Volumn 14, Issue 1, 1999, Pages 60-64

  Spandorfer, S D ^a   Neuer, A ^a   La Verda, D ^b   Byrne, G ^b   Liu, H C ^a   Rosenwaks, Z ^a   Witkin, S S ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

10 kDa heat shock protein; Chlamydia trachomatis; Hydrosalpinx; IVF outcome

Indexed keywords

ANTIBODY; HEAT SHOCK PROTEIN;

ADULT; ARTICLE; CHLAMYDIA TRACHOMATIS; FEMALE; FERTILIZATION IN VITRO; HUMAN; HYDROSALPINX; IMMUNITY; INFERTILITY; MAJOR CLINICAL STUDY; MALE INFERTILITY; PREGNANCY; UTERINE TUBE OCCLUSION;

EID: 0032937669     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: 10.1093/humrep/14.1.60     Document Type: Article

References (17)

1. Cates, W., Joesoef, M.R. and Goldman, M.B. (1993) Atypical pelvic inflammatory disease: can we identify clinical predictors? Am. J. Obstet. Gynecol., 169, 341-346.
2. Claman, P., Amini, M.N., Peeling, R.W. et al. (1996) Does serologic evidence of remote Chlamydia trachomatis infection and its heat shock protein affect in vitro-fertilization transfer outcome? Fertil. Steril., 65, 146-149.
3. Davis, O.K. and Rosenwaks, Z. (1996) In vitro fertilization. In Adashi, E., Rock, J.A., Rosenwaks, Z. (eds), Reproductive Endocrinology, Surgery, and Technology. Lippincott-Raven, Philadelphia, pp. 2319-2334.
4. Eggert-Kruse, W., Rohr, G., Demiracka, T. et al. (1997) Chlamydial serology in 1303 asymptomatic women subfertile couples. Hum. Reprod., 12, 1464-1475.
5. Jones, R.B., Ardery, B.R., Hui, S.L. et al. (1982) Correlation between serum antichlamydial antibodies and tubal factor as a cause of infertility. Fertil. Steril., 38, 553-558.
6. Katz, E., Akman M.A., Damewood, M.D. and Garcia, J.E. (1996) Deleterious effect of the presence of hydrosalpinx on implantation and pregnancy rates with in vitro fertilization. Fertil. Steril., 66, 122-125.
7. LaVerda, D. and Byrne, G.I. (1997) Use of monoclonal antibodies to facilitate identification, cloning and purification of Chlamydia trachomatis hsp10. J. Clin. Microbiol, 35, 1209-1215.
8. th Annual Meeting, San Antonio, TX, USA, pp. 45.
9. Morrison, R.P., Belland, R.J., Lyng, K. and Cladwell, H.D. (1989) Chlamydial disease pathogenesis. Ocular hypersensitivity elicited by a genus-specific 57-kD protein. J. Exp. Med., 169, 663-675.
10. Mukherjee, T., Copperman, A., McCaffrey, C. et al. (1996) Hydrosalpinx has embryotoxic effects on murine embryogenesis: a case for prophylactic salpingectomy. Fertil. Steril., 66, 851-853.
11. Neuer, A., Lam, K.N., Tiller, F.W. et al. (1998) Humoral immune response to membrane components of Chlamydia trachomatis and expression of human 60 kDa heat shock protein in follicular fluid of in-vitro fertilization patients. Hum. Reprod., 12, 925-929.
12. Sharara, F.I., Scott, R.T., Marut, E.L. and Queenan, J.T. (1996) In-vitro fertilization outcome in women with hydrosalpinx. Hum. Reprod., 11, 526-530.
13. Strandell, A., Waldenstrom, Nilsson, L. and Hamberger, L. (1994) Hydrosalpinx reduces in-vitro fertilization/ embryo transfer pregnancy rates. Hum. Reprod., 9, 861-863.
14. Vandromme, J., Chasse, E., Lejeune, B. et al. (1995) Hydrosalpinges in in-vitro fertilization: an unfavorable prognostic feature. Hum. Reprod., 10, 576-579.
15. Witkin, S.S., Jeremias, J., Toth, M. and Ledger, W.J. (1993) Cell-mediated immune response to the recombinant 57-kDa heat shock protein of Chlamydia trachomatis in women with salpingitis. J. Infect. Dis., 167, 1379-1383.
16. Witkin, S.S., Sultan, K.M., Neal, Jeremias, J. et al. (1994) Unsuspected Chlamydia trachomatis infection and in vitro fertilization outcome. Am. J. Obstet. Gynecol., 171, 1208.
17. Witkin, S.S., Kligman, I., Grifo, J.A. and Rosenwaks, Z. (1995) Chlamydia trachomatis detected by PCR in cervices of culture-negative women correlates with adverse in vitro fertilization outcome. J. Inf. Dis., 171, 1657-1659.