Mechanisms of bioprosthetic heart valve failure: Fatigue causes collagen denaturation and glycosaminoglycan loss

Journal of Biomedical Materials Research

Volumn 46, Issue 1, 1999, Pages 44-50

  Vyavahare, Narendra ^a   Ogle, Matthew ^b   Schoen, Frederick J ^c   Zand, Robert ^d   Claire Gloeckner, D ^e   Sacks, Michael ^e   Levy, Robert J ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b St Jude Medical Inc USA   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d UNIVERSITY OF MICHIGAN   (United States)

^e University of Miami College of Engineering   (United States)

Author keywords

Biomechanical strength; Bioprosthetic heart valve degeneration; FTIR spectroscopy; In vitro accelerated fatigue; Type I collagen

Indexed keywords

ALDEHYDES; BENDING STRENGTH; BIOMECHANICS; COLLAGEN; DEFORMATION; FATIGUE OF MATERIALS; FOURIER TRANSFORM INFRARED SPECTROSCOPY; MOLECULAR STRUCTURE;

COLLAGEN DENATURATION; GLUTARALDEHYDE; GLYCOSAMINOGLYCAN;

HEART VALVE PROSTHESES;

COLLAGEN TYPE 1; GLYCOSAMINOGLYCAN;

ANIMAL TISSUE; ARTICLE; BIOMECHANICS; BIOPROSTHESIS; FATIGUE; HEART VALVE PROSTHESIS; HISTOPATHOLOGY; INFRARED SPECTROSCOPY; NONHUMAN; PATHOGENESIS; PROSTHESIS FAILURE; PROTEIN DENATURATION; SWINE;

ANIMALS; AORTIC VALVE; BIOMECHANICS; BIOPROSTHESIS; COLLAGEN; EQUIPMENT FAILURE ANALYSIS; HEART VALVE PROSTHESIS; PROSTHESIS FAILURE; SPECTROPHOTOMETRY, INFRARED; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SWINE;

EID: 0032937211     PISSN: 00219304     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4636(199907)46:1<44::AID-JBM5>3.0.CO;2-D     Document Type: Article

References (28)

1. Edmunds LH, Clark RE, Cohn LH, Grunkemeier GL, Miller DC, Weisel RD. Guidelines for reporting morbidity and mortality after cardiac valvular operations. Eur J Cardio Thorac Surg 1996;10:812-816.
2. Fann JI, Miller DC, Moore KA, Mitchell RS, Oyer PE, Stinson EB, Robbins RC, Reitz BA, Shumway NE. Twenty-year clinical experience with porcine bioprostheses. Ann Thorac Surg 1996; 62:1311-1312.
3. Pelletier L, Carrier M, Leclerc Y, Lepage G, DeGuise P, Dyrda I. Porcine versus pericardial bioprostheses: A comparison of late results in 1,593 patients. Ann Thorac Surg 1989;47:352-361.
4. Potkin BN, McIntosh CL, Cannon RB, Roberts WC. Bioprostheses in tricuspid and mitral valve positions for 95 months with heavier calcific deposits on the right-sided valve. Am J Cardiol 1988;61:947-949.
5. Schoen FJ, Collins JJ, Cohn LH. Long-term failure rate and morphologic correlations in porcine bioprosthetic heart valves. Am J Cardiol 1983;51:957-964.
6. Thubrikar MJ, Deck JD, Aouad J, Nolan SP. Role of mechanical stress in calcification of aortic bioprosthetic valves. J Thorac Cardiovasc Surg 1983;86:115-125.
7. Sabbah HN, Hamid MS, Stein PD. Mechanical stresses on closed cusps of porcine bioprosthetic valves: correlation with sites of calcification. Ann Thorac Surg 1986;42:93-96.
8. Grabenwoger M, Grimm M, Eybl E, Kadletz M, Havel M, Kostler P, Plenk H, Bock P, Wolner E. New aspects of the degeneration of bioprosthetic heart valves after long-term implantation. J Thorac Cardiovasc Surg 1992;104:14-21.
9. Jorge HE, Fernandez P, de la Torre Escudero C, Zurita N, Garcia M, Paez JM, Castillo OJ. Influence of stress on calcification of delipidated bovine pericardial tissue employed in construction of cardiac valves. J Biomed Mater Res 1996;30: 411-415.
10. Ferrans VJ, Spray TL, Billingham ME, Roberts WC. Structural changes in glutaraldehyde-treated porcine heterografts used as substitute cardiac valves: Transmission and scanning electron microscopic observations in 12 patients. Am J Cardiol 1978;41: 1159-1184.
11. Johnson DM, Chwirut DJ, Regnault WF. FDA's requirements for in-vitro performance data for prosthetic heart valves. J Heart Valve Dis 1994;3:228-234.
12. Bitter T, Muir HM. A modified uronic acid carbazole reaction. Anal Biochem 1962;4:330-334.
13. Murata K. Acidic glycosaminoglycans in human heart valves. J Mol Cell Cardiol 1981;13:281-292.
14. Vyavahare NR, Hirsch D, Learner E, Baskin JZ, Schoen FJ, Bianco R, Kruth HS, Zand R, Levy RJ. Prevention of bioprosthetic heart valve calcification by ethanol preincubation: efficacy and mechanism. Circulation 1997;95:479-488.
15. Xie J, Zhou J, Fung YC. Bending of blood vessel wall: stress-strain laws of the intima-media and adventitial layers. ASME J Biomech Eng 1995;117:136-145.
16. Susi H, Ard JS, Carroll RJ. The infrared spectrum and water binding of collagen as a function of relative humidity. Biopolymers 1971;10:1597-1604.
17. Doyle BB, Bendit EG, Blout ER. Infrared spectroscopy of collagen and collagen like peptides. Biopolymers 1975.14:937-957.
18. Jakobsen RJ, Brown LL, Hutson TB, Fink DJ, Veis A. Intermolecular interactions in collagen self-assembly as revealed by Fourier transform infrared spectroscopy. Science 1983;220: 1288-1290.
19. Lazarev YA, Grishkovsky A, Khromova TB. Amide I band of IR spectrum and structure of collagen and related polypeptides. Biopolymers 1985;24:1449-1478.
20. Payne KJ, Veis A. Fourier transform IR spectroscopy of collagen and gelatin solutions: deconvolution of the amide I band for conformational studies. Biopolymers 1988;27:1749-1760.
21. Renugopalkrishnan V, Chandrakasan G, Moore S, Hutson TB, Berney CV, Bhatnagar R. Bound water in collagen. Evidence from Fourier transform infrared and Fourier transform infrared photoacoustic spectroscopic study. Macromolecules 1989; 22:4121-4124.
22. 2O demonstrates that collagen monomers undergo a conformational transition prior to thermal self-assembly in vitro. Biochemistry 1991;30:2372-2377.
23. Jackson M, Choo LP, Watson PH, Halliday WC, Mantsch HH. Beware of connective tissue proteins: assignment and implications of collagen absorptions in infrared spectra of human tissue. Biochim Biophys Acta 1995;1270:1-6.
24. Mako WJ, Calabro A, Ratliff NB, Vesely I. Loss of glycosaminoglycans (GAGs) from implanted bioprosthetic heart valves. In: Proceedings of the American Heart Association, 70th Scientific Sessions; Orlando, FL. 1997.
25. Schoen FJ. Aortic valve structure-function correlations: role of elastic fibers no longer a stretch of the imagination [Editorial]. J Heart Valve Dis 1997;6:1-6.
26. Thubrikar M, editor. The aortic valve. Boca Raton, FL: CRC Press; 1990.
27. Blumenthal NC. Mechanisms of inhibition of calcification. Clin Orthop Rel Res 1989;247:279-89.
28. Sacks MS, Smith DB. Effects of accelerated testing on porcine heart valve fiber architecture. Biomaterials. In press.