Stratum corneum thiol protease (SCTP): A novel cysteine protease of late epidermal differentiation

Archives of Dermatological Research

Volumn 291, Issue 5, 1999, Pages 260-268

  Watkinson, Allan ^a  

^a UNILEVER RESEARCH   (United Kingdom)

Author keywords

Cathepsin; Cysteine protease; Desquamation; Gelatinase; Stratum corneum

Indexed keywords

ACID PROTEINASE; ANTIBODY; CALCIUM; CATHEPSIN; CONCANAVALIN A; CYSTEINE; CYSTEINE PROTEINASE; GELATIN; GLYCOPEPTIDASE; GLYCOPROTEIN; KETONE DERIVATIVE; OLIGOSACCHARIDE; STRUCTURAL PROTEIN; THIOL PROTEINASE;

AFFINITY CHROMATOGRAPHY; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CHEMICAL ANALYSIS; DERMIS; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME SPECIFICITY; ENZYME SUBUNIT; ENZYME SYNTHESIS; EPIDERMIS; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; KERATINOCYTE; MOLECULAR WEIGHT; PH; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN QUATERNARY STRUCTURE; STRATUM CORNEUM; ZYMOGRAPHY;

BLOTTING, WESTERN; CATHEPSINS; CELLS, CULTURED; CYSTEINE ENDOPEPTIDASES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; EPIDERMIS; GELATIN; GELATINASES; HUMANS; HYDROGEN-ION CONCENTRATION; KERATINOCYTES; PROTEASE INHIBITORS;

EID: 0032937063     PISSN: 03403696     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004030050406     Document Type: Article

References (46)

1. Watt FM (1989) Terminal differentiation of epidermal keratinocytes. Curr Opin Cell Biol 1:1107-1115
2. Elias PM, Menon GK (1991) Structural and lipid biochemical correlates of the epidermal permeability barrier. Adv Lipid Res 24:1-26
3. Brody I (1954) An ultrastructural study on the role of the keratohyalin granules in the keratinization process. J Ultrastruct Res 3:84-104
4. Lavker RM, Matoltsy AG (1970) Formation of horny cells: the fate of cell organelles and differentiation products in ruminal epithelium. J Cell Biol 144:501-12
5. Holbrook KA (1989) Biologic structure and function: perspectives on morphologic approaches to the study of the granular layer keratinocytes. J Invest Dermatol 92:84S-104S
6. Bowden PE, Cunliffe WJ (1981) Modification of human prekeratin during epidermal differentiation. Biochem J 199:145-154
7. Scott IR, Harding CR, Barrett JG (1982) Histidine-rich protein of the keratohyalin granules:source of the free amino acids, urocanic acid and pyrrolidone carboxylic acid in mammalian stratum corneum. Biochim Biophys Acta 669:65-78
8. Scott IR, Harding CR (1986) Filaggrin breakdown to water binding compounds during development of the rat stratum corneum is controlled by the water activity of the environment. Dev Biol 115:84-92
9. Egelrud T, Hofer P-≈, Lundström A (1989) Proteolytic degradation of desmosomes in plantar stratum corneum leads to cell dissociation in vitro. Acta Derm Venereol 68:93-97
10. Lundström A, Egelrud T (1990) Cell shedding from human plantar skin in vitro:evidence that two different types of protein structures are degraded by a chymotrypsin-like enzyme. Arch Dermatol Res 282:234-237
11. Egelrud T, Lundström A (1989) Immunochemical analysis of the distribution of the desmosomal protein desmoglein I in different layers of plantar epidermis. Acta Derm Venereol 69:470-476
12. Lundström A, Egelrud T (1990) Evidence that cell shedding from plantar stratum corneum in vitro involves endogenous proteolysis of the desmosomal protein desmoglein I. J Invest Dermatol 94:216-220
13. Suzuki Y, Nomura J, Koyama J, Horii I (1994) The role of proteases in stratum corneum:involvement in stratum corneum desquamation. Arch Dermatol Res 286:249-253
14. Suzuki Y, Koyama J, Moro O, Horii, I, Kikuchi K, Tanida M, Tagami H (1996) The role of two endogenous proteases of the stratum corneum in degradation of desmoglein-1 and their reduced activity in the skin of ichthyotic patients. Br J Dermatol 134:460-464
15. Watkinson A, Rogers J, Harding C (1998) Characterization of the effect of protease inhibitors and lipids on human recombinant stratum corneum chymotryptic enzyme supports a role in desquamation. J Invest Dermatol 110:672
16. Long S, Banks J, Watkinson A, Harding C, Rawlings AV (1996) Desmocollin 1:a key marker for desmosome processing in the stratum corneum. J Invest Dermatol 106:397
17. Chapman SJ, Walsh A (1990) Desmosomes, corneosomes and desquamation. An ultrastructural study of adult pig epidermis. Arch Dermatol Res 282:304-310
18. Rawlings AV, Watkinson A, Rogers J, Mayo A-M, Hope J, Scott IR (1994) Abnormalities in stratum corneum structure, lipid composition and desmosome degradation in soap-induced winter xerosis. J Soc Cosmet Chem 45:203-220
19. Egelrud T, Lundström A (1991) A chymotrypsin-like proteinase that may be involved in desquamation in plantar stratum corneum. Arch Dermatol Res 283:108-112
20. Lundström A, Egelrud T (1991) Stratum corneum chymotryptic enzyme:a proteinase which may be generally present in the stratum corneum and with a possible involvement in desquamation. Acta Derm Venereol 71:471-474
21. Hansson L, Strömqvist M, Bäckman A, Wallbrandt P, Carlstein A, Egelrud T (1994) Cloning, expression and characterization of stratum corneum chymotryptic enzyme. J Biol Chem 269:19420-19426
22. Franzke CW, Wiedow O, Christophers E (1997) Detection of trypsin-like activity in human stratum corneum. J Invest Dermatol 109:431
23. Suzuki Y, Nomura J, Hori J, Koyama J, Takahashi M, Horii I (1993) Detection and characterization of endogenous protease associated with desquamation of stratum corneum. Arch Dermatol Res 285:372-377
24. Watkinson A, Smith CG, Rawlings AV (1994) Identification and localization of tryptic and chymotryptic-like enzymes in human stratum-corneum. J Invest Dermatol 102:637
25. Hara K, Fukayam, K, Sakai H, Yamamoto K, Epstein WL (1993) Purification and immunohistochemical localization of aspartic proteinases in rat epidermis. J Invest Dermatol 100:394-399
26. Fräki JE, Hopsu-Havu VK (1972) Skin proteases. Fractionation and characterization. Arch Dermatol Forsch 243:52-66
27. Mier PD, Hurk JJMA van den (1976) Lysosomal hydrolases of the epidermis; changes in disease. Br J Dermatol 95:271-274
28. Fukuyama K, Ito Y, Yabe K, Epstein WL (1985) Immunological detection of a cysteine protease in the skin and other tissues. Cell Tissue Res 240:417-423
29. Fräki JE (1976) Human skin proteases. Separation and characterization of two acid proteases resembling cathepsin B1 and cathepsin D and of an inhibitor of cathepsin B1. Arch Dermatol Res 255:317-330
30. Ito Y, Fukuyama K, Yabe K, Epstein WL (1984) Purification and properties of aminoendopeptidase from rat epidermis. J Invest Dermatol 83:265-269
31. 2+ in the second stage. J Biol Chem 268:25139-25145
32. Laemmli UK (1970) Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature 227:680-685
33. Horie N, Fukuyama K, Ito Y, Epstein WL (1984) Detection and characterization of epidermal proteinases by polyacrylamide gel electrophoresis. Comp Biochem Physiol 77B:349-353
34. Benyon RJ, Bond JS (eds) (1989) Proteolytic enzymes:a practical approach. IRL Press, Oxford
35. Rinne A, Kirschke H, Jarvinen M, Hopsu-Havu VK, Wiederanders B, Bohley P (1985) Localization of cathepsin H and its inhibitor in the skin and other stratified epithelia. Arch Dermatol Res 277:190-194
36. Knapp AC, Franke WW, Heid H, Hatzfeld M, Jorcano JL, Moll R (1986) Cytokeratin no. 9, an epidermal type I keratin characteristic of a special program of keratinocyte differentiation displaying body site specificity. J Cell Biol 103:657-667
37. Moll I, Heid H, Franke WW, Moll R (1987) Distribution of a special subset of keratinocytes characterized by the expression of cytokeratin 9 in adult and fetal human epidermis of various body sites. Differentiation 33:254-265
38. Egelrud T, Stigbrand T (1989) Regional variations in cytokeratin expression in palmo-plantar epidermis. Acta Derm Venereol 69:373-379
39. Yamamoto H, Murawaki Y, Kawasaki H (1992) Collagenolytic cathepsin B and L activity in experimental fibrotic liver and human liver. Res Commun Chem Pathol Pharmacol 76:95-112
40. Burleigh MC, Barrett AJ, Lazarus GS (1974) Cathepsin B1: a lysosomal enzyme that degrades native collagen. Biochem J 137:387-398
41. Reichert U, Michel S, Schmidt R (1993) The cornified envelope: a key structure of terminally differentiating keratinocytes. In: Darmon M, Blumenberg M (eds) Molecular biology of the skin:the keratinocyte. Academic Press, London
42. King IA, Wood MJ, Fryer PR (1989) Desmoglein II-derived glycopeptides in human epidermis. J Invest Dermatol 92:22-26
43. Watkinson A, Rawlings AV (1996) Stratum corneum thiol cathepsin-like enzyme in skin care compositions. US patent number 5545399
44. Brysk MM, Rajaraman S, Penn P, Barlow E (1988) Glycoproteins modulate adhesion in terminally differentiated keratinocytes. Cell Tissue Res 253:657-663
45. Simon M, Montezin M, Guerrin M, Durieux JJ, Serre G (1997) Characterization and purification of human corneodesmosin, an epidermal basic glycoprotein associated with corneocyte-specific modified desmosomes. J Biol Chem 272:31770-31776
46. Lundstrom A, Serre G, Haftek M, Egelrud T (1994) Evidence for a role of corneodesmosin, a protein which may serve to modify desmosomes during cornification, in stratum corneum cell cohesion and desquamation. Arch Dermatol Res 286:369-375