Use of transdermal amitriptyline gel in a patient with chronic pain and depression

Pharmacotherapy

Volumn 19, Issue 2, 1999, Pages 236-239

  Scott, Mollie A ^a   Letrent, Kristen J ^a   Hager, Kellie L ^a   Burch, Jennifer L ^b  

^a Campbell University   (United States)

^b Central Pharmacy   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMITRIPTYLINE; DRUG METABOLITE; MERCAPTOPURINE; MORPHINE; NORTRIPTYLINE; PREDNISONE; TRICYCLIC ANTIDEPRESSANT AGENT;

ABDOMINAL PAIN; ADULT; ARTICLE; CASE REPORT; CHRONIC PAIN; CROHN DISEASE; DEPRESSION; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; HUMAN; INTRAMUSCULAR DRUG ADMINISTRATION; MALE; MENTAL DISEASE; PAIN; TRANSDERMAL DRUG ADMINISTRATION; TREATMENT OUTCOME;

ADMINISTRATION, CUTANEOUS; ADULT; AMITRIPTYLINE; ANTIDEPRESSIVE AGENTS, TRICYCLIC; CHRONIC DISEASE; DEPRESSION; GELS; HUMANS; INFLAMMATORY BOWEL DISEASES; MALE; PAIN;

EID: 0032936686     PISSN: 02770008     EISSN: None     Source Type: Journal    
DOI: 10.1592/phco.19.3.236.30922     Document Type: Article

References (19)

1. Jacox A, Carr DB, Payne R, et al. Management of cancer pain. Clinical practice guideline no. 9. AHCPR publication no. 94-0592. Rockville, MD: U.S. Department of Health and Human Services, 1994.
2. Cleeland CS, Gonin R, Hatfield AK, et al. Pain and its treatment in outpatients with metastatic cancer. N Engl J Med 1994;330:592-6.
3. Callies Al, Popkin MK. Antidepressant treatment of medical-surgical inpatients by nonpsychiatric physicians. Arch Gen Psychiatry 1987;44:157-60.
4. Rush JA, Golden WE, Hall GW, et al. Depression in primary care, vol 1. Detection and diagnosis. Clinical practice guideline no. 5. AHCPR publication no. 93-0550. Rockville, MD: U.S. Department of Health and Human Services, 1993.
5. Rush JA, Golden WE, Hall GW, et al. Depression in primary care, vol 2. Treatment of major depression. Clinical practice guideline no. 5. AHCPR publication no. 93-0551. Rockville, MD: U.S. Department of Health and Human Services, 1993.
6. Egbunike IG, Chaffee BJ. Antidepressants in the management of chronic pain syndromes. Pharmacotherapy 1990;10:262-70.
7. Watson CP. Antidepressant drugs as adjuvant analgesics. J Pain Symptom Manage 1994;9:392-405.
8. McEvoy GK, ed. AHFS 98 drug information. Bethesda, MD: American Society of Health-System Pharmacists, 1998:1471-6.
9. Benet LZ, Kroetz DL, Sheiner LB. The dynamics of drug absorption, distribution, and elimination. In: Hardman JG, Limbird LE, Molinoff PB, Ruddon RW, Gilman AG, eds. Goodman and Gilman's the pharmacological basis of therapeutics, 9th ed. New York: McGraw-Hill, 1996:3-27.
10. Bailey DN. Percutaneous absorption of tricyclic antidepressanls: amitriptyline, nortriptyline, imipramine, and desipramine. J Anal Toxicol 1990;14:217-18.
11. Williman H, Walde P, Luisi PI, Gazzaniga A, Stroppolo F. Lecithin organogel as matrix for transdermal transport of drugs. J Pharm Sci 1992;81:871-4.
12. Allen LV. Ketoprofen gel. US Pharmacist 1993;18:98-100.
13. Preskorn SH. Pharmacokinetics of antidepressants. Why and how they are relevant to treatment. J Clin Psychiatry 1993;54(9, suppl): 14-34.
14. Burch JE, Herries DG. The demethylation of amitriptyline administered by oral and intramuscular routes. Psychopharmacology 1983;80:249-53.
15. Mellstrom B, Alvan G, Bertilisson L, et al. Nortriptyline formation after single oral and intramuscular doses of amitriptyline. Clin Pharmacol Ther 1982;32:664-7.
16. Sabroe RA, Kennedy CT, Archer CB. The effects of topical doxepin on responses to histamine, substance P and prostaglandin E2 in human skin. Br J Dermatol. 1997;137: 338-90.
17. Smith PF, Corelli RL. Doxepin in the management of pruritus associated with allergic cutaneous reactions. Ann Pharmacother 1997;31:633-5.
18. Drake LA, Millikan LE. The antipruritic effect of 5% doxepin cream in patients with eczematous dermatitis: doxepin study group. Arch Dermatol 1995;131:1403-8.
19. Baldessarini RJ. Drugs and the treatment of psychiatric disorders: depression and mania. In: Hardman JG, Limbird LE, Molinoff PB, Ruddon RW, Gilman AG, eds. Goodman and Gilman's the pharmacological basis of therapeutics, 9th ed. New York: McGraw-Hill, 1996:431-59.