Immunohistochemical localization of metallothionein in the developing teeth of cadmium-injected rats

Archives of Oral Biology

Volumn 44, Issue 1, 1999, Pages 49-53

  Tamura, Yukihiko ^a   Wysocki, George P ^a   Cherian, M George ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Ameloblasts; Cadmium; Enamel organ; Metallothionein

Indexed keywords

CADMIUM; METALLOTHIONEIN;

AMELOBLAST; ANIMAL; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; CYTOLOGY; DRUG EFFECT; EPITHELIUM CELL; IMMUNOHISTOCHEMISTRY; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; METABOLISM; NONHUMAN; PROTEIN DETERMINATION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; RAT; RAT STRAIN; TOOTH DEVELOPMENT; TOOTH FLORA;

AMELOBLASTS; ANIMALS; CADMIUM; ENAMEL ORGAN; EPITHELIAL CELLS; IMMUNOHISTOCHEMISTRY; INJECTIONS, INTRAPERITONEAL; MALE; METALLOTHIONEIN; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0032936452     PISSN: 00039969     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-9969(98)00088-0     Document Type: Article

References (19)

1. Banerjee D., Onosaka S., Cherian M.G. Immunohistochemical localization of metallothionein in specific epithelial cell nucleus and cytoplasm of rat liver and kidney. Toxicol. 24:1982;95-105.
2. Bawden J.W., Hammarstrom L.E. Distribution of cadmium in developing teeth and bone of young rats. Scand J Dent Res. 83:1975;179-186.
3. Cherian M.G. The significance of the nuclear and cytoplasmic localization of metallothionein in human liver and tumour cells. Environ Hlth Perspect. 102:1994;131-135.
4. Cherian, M.G., 1995. Metallothionein and its interaction with metals. In: R.A. Goyer, M.G. Cherian (Ed.). Toxicology of Metals, Biochemical Aspects. Handbook of Experimental Pharmacology, Vol. 115. Springer-Verlag Inc., Berlin, pp. 121-132.
5. Curzon M.E.J., Crocker D.C. Relationships of trace elements in human tooth enamel to dental caries. Arch Oral Biol. 23:1978;647-653.
6. Danielson K.G., Ohi S., Huang P.C. Immunochemical detection of metallothionein in specific epithelial cells of rat organs. Proc Natl Acad Sci USA. 79:1982;2301-2304.
7. Friberg, L., Kjellstrom, T., Nordberg, G.F., 1986. L.M. Friberg, G.F. Nordberg, V.B. Vouk (Ed.). Handbook on the Toxicology of Metals, Vol. II. Elsevier, Oxford, pp. 130-184.
8. Hammer D.H. Metallothionein. Ann Rev Biochem. 55:1986;913-951.
9. Hiratsuka H., Katsuta O., Toyota N., Tsuchitani M., Akiba T., Marumo F., Umemura T. Iron deposition at mineralization fronts and osteoid formation following chronic cadmium exposure in ovariectomized rats. Toxicol App Pharmacol. 143:1997;348-356.
10. Itokawa Y., Abe T., Tabei R., Tanaka S. Renal and skeletal lesions in experimental cadmium poisoning. Arch Environ Hlth. 28:1974;149-154.
11. Mercado R.C., Bibby B.G. Trace element effects on enamel pigmentation, incisor growth and molar morphology in rats. Arch Oral Biol. 18:1973;629-635.
12. Margoshes M., Valle B.L. A cadmium protein from equine kidney cortex. J Am Chem Soc. 799:1957;4813-4814.
13. Nartey N.O., Banerjee D., Cherian M.G. Immunohistochemical localization of metallothionein in cell nucleus and cytoplasm of fetal human liver and kidney and its changes during development. Pathol. 19:1987;233-238.
14. Nogawa K., Ishizaki A. A comparison between cadmium in rice and renal effects among inhabitants of the Jinzu River Basin. Environ Res. 18:1979;410-420.
15. Shearer T.R., Britton J.L., Desart D.J., Johnson J.R. Influence of cadmium on caries and the cariostatic properties of fluoride in rats. Arch Environ Hlth. 35:1980;176-180.
16. Shimada A., Irie M., Kojima S., Kobayashi K., Yamano Y., Umemura T. Immunohistochemical localization of metallothionein in the olfactory pathway of dogs. J Vet Med Sci. 58:1996;983-988.
17. Skabo S.J., Holloway A.F., West A.K., Chuah M.I. Metallothioneins 1 and 2 are expressed in the olfactory mucosa of mice in untreated animals and during the regeneration of the epithelial layer. Biochem Biophys Res Comm. 232:1997;136-142.
18. 45Ca in nonpregnant mice on a calcium-deficient diet: Evidence of direct effect of cadmium on bone. Toxicol App Pharmacol. 120:1993;228-239.
19. Warshawsky H., Smith C.E. Morphological classification of rat incisor ameloblasts. Anat Rec. 179:1974;423-445.