In vitro and in vivo vasodilatory activity of barnidipine and its enantiomers

Biological and Pharmaceutical Bulletin

Volumn 22, Issue 2, 1999, Pages 151-156

  Inagaki, Osamu ^a   Asano, Masaharu ^a   Takenaka, Toichi ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

1,4 dihydropyridine; Barnidipine; Enantiomer; Stereoselectivity

Indexed keywords

CALCIUM ANTAGONIST; DIHYDROPYRIDINE; MEPIRODIPINE; NICARDIPINE; NIFEDIPINE; NITRENDIPINE; POTASSIUM CHLORIDE; PYRROLIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA CONSTRICTION; AREA UNDER THE CURVE; ARTICLE; CONCENTRATION RESPONSE; CORONARY ARTERY BLOOD FLOW; DOG; DRUG POTENCY; FEMALE; GUINEA PIG; INTRAARTERIAL DRUG ADMINISTRATION; ISOMER; MALE; NONHUMAN; STEREOCHEMISTRY; VASODILATATION;

EID: 0032936025     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.22.151     Document Type: Article

References (21)

1. Waters D., Can. J. Cardiol., 13, 757-766 (1997).
2. Opie L. H., Am. J. Hypertens., 10, 565-577 (1997).
3. Zannad F., J. Hypertens., 14 (Supple. 3), S37-S40 (1996).
4. van Zwieten P. A., Pfaffendorf M., J. Hypertens., 11 (Supple. 1), S3-S11 (1993).
5. Shimada S., Nakajima Y., Yamamoto K., Sawada Y., Iga T., Biol. Pharm. Bull., 19, 430-437 (1996).
6. Towart R., Wehinger E., Meyer H., Naunyn-Schmiedeberg's Arch. Pharmacol., 317, 183-185 (1981).
7. Hof R. P. Ruegg U. T., Hof A., Vogel A., J. Cardiovasc. Pharmacol., 7, 689-693 (1985).
8. Takenaka T., Miyazaki I., Asano M., Higuchi S., Maeno H., Jpn. J. Pharmacol., 32, 665-670 (1982).
9. Hof R. P., Hof A., Ruegg U. T., Cook N. S., Vogel A., J. Cardiovasc. Pharmacol., 8, 221-226 (1986).
10. Franckowiak G., Bechem M., Schramm M., Thomas G., Eur. J. Pharmacol., 114, 223-226 (1985).
11. Tamazawa K., Arima H., Kojima T., Isomura Y., Okada M., Fujita S., Furuya T., Takenaka T., Inagaki O., Terai M., J. Med. Chem., 29, 2504-2511 (1986).
12. Briand V., Laurent S., Tsoucaris-Kupfer D., Legrand M., Brisac A. M., Schmitt H., Eur. J. Pharmacol., 150, 43-50 (1988).
13. Yamada S., Matsuoka Y., Kato Y., Kimura R., Inagaki O., J. Pharmacol. Exp. Ther., 262, 589-594 (1992).
14. Nakayama K., Kashiwabara T., Yamada S., Tanaka Y., Arzneim.-Forsch., 39, 50-55, (1989).
15. van Zwieten P. A., Pfaffendorf M., J. Hypertens., 11 (Supple. 6), S3-S8 (1993).
16. Herbette L. G., Vant-Erve Y. M., Rhodes D. G., J. Mol. Cell Cardiol., 21, 187-201 (1989).
17. Rhodes D. G., Sarmiento J. G., Herbette L. G., Mol. Pharmacol., 27, 612-623 (1985).
18. Mounier-Vehier C., Bernaud C., Carré A., Lequeuche B., Hotton J. M., Charpentier J. C., Am. J. Hypertens., 11, 478-486 (1998).
19. Gross G. J., Farber N. E., Pieper G. M., Cardiovasc. Drug Ther., 3, 535-543 (1989).
20. Satoh K., Yamamoto A., Hoshi K., Ichihara K., Jpn. J. Pharmacol., 76, 369-376 (1998).
21. Alderman M. H., Cohen H., Roqué R., Madhaven S., Lancet, 349, 594-598 (1997).