Optimal timing of liver transplantation for patients with primary biliary cirrhosis: Use of prognostic modelling

Journal of Hepatology

Volumn 30, Issue 2, 1999, Pages 285-292

  Christensen, Erik ^b   Gunson, Bridget ^a   Neuberger, James ^a  

^a QUEEN ELIZABETH HOSPITAL   (United Kingdom)

^b BISPEBJERG HOSPITAL   (Denmark)

Author keywords

Cox regression model; Primary biliary cirrhosis; Prognostic factors; Survival analysis; Transplantation

Indexed keywords

ADULT; ARTICLE; FEMALE; HUMAN; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; PRIMARY BILIARY CIRRHOSIS; PRIORITY JOURNAL; PROGNOSIS; STATISTICAL ANALYSIS; SURVIVAL; TREATMENT OUTCOME;

EID: 0032935944     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(99)80075-0     Document Type: Article

References (28)

1. Christensen E, Crowe J, Doniach D, Popper H, Ranek L, Rodes J, et al. Clinical pattern and course of disease in primary biliary cirrhosis based on an analysis of 236 patients. Gastroenterology. 78:1980;236-246.
2. Christensen E, Neuberger J, Crowe J, Altman DG, Popper H, Portmann B, et al. Beneficial effect of azathioprine and prediction of prognosis in primary biliary cirrhosis. Final results of an international trial. Gastroenterology. 89:1985;1084-1091.
3. Kaplan MM, Alling DW, Zimmerman HJ, Wolfe HJ, Serpersky RA, Hirsch GS, et al. A prospective trial of colchicine for primary biliary cirrhosis. N Engl J Med. 315:1986;1448-1454.
4. Lombard M, Portmann B, Neuberger J, Williams R, Tygstrup N, Ranek L, et al. Cyclosporin A treatment in primary biliary cirrhosis. Results of a long-term placcbo-controlled trial. Gastroenterology. 104:1993;519-526.
5. Kaplan MM, Knox TA. Treatment of primary biliary cirrhosis with low-dose weekly methotrexate. Gastroenterology. 101:1991;1332-1338.
6. Mitchison H, Palmer J, Bassendine M, Watson AJ, Record CO, James OF. A controlled trial of prednisolone treatment in primary biliary cirrhosis. J Hepatol. 15:1992;336-344.
7. Lindor KD, Therneau TM, Jorgensen RA, Malinchoc M, Dickson ER. Effects of ursodeoxycholic acid on survival in patients with primary biliary cirrhosis. Gastroenterology. 110:1996;1515-1518.
8. Neuberger JM, Gunson BK, Buckels JAC, Elias E, McMaster P. Referral of patients with primary biliary cirrhosis for liver transplantation. Gut. 31:1990;1069-1072.
9. Roll J, Boyer JL, Barry D, Klatskin G. The prognostic importance of clinical and histologic features in asymptomatic and symptomatic primary biliary cirrhosis. N Engl J Med. 308:1983;1-7.
10. Dickson ER, Grambsch PM, Fleming TR, Fisher LD, Langworthy A. Prognosis in primary biliary cirrhosis: a model for decision making. Hepatology. 10:1989;1-7.
11. Goudie BM, Burt AD, Macfarlane GJ, Boyle P, Gillis CR, MacSween RNM, et al. Risk factors and prognosis in primary biliary cirrhosis. Am J Gastroenterol. 84:1989;713-716.
12. Rydning A, Schrumpf E, Abdelnoor M, Elgio K, Jenssen E. Factors of prognostic importance in primary biliary cirrhosis. Scand J Gastrocnterol. 25:1990;119-126.
13. Biagini MR, Guardascione M, Raskino C, McIntyre N, Surrenti C, Burroughs AK. Poor prognostication for survival of individual PBC patients with Cox models. J Hepatol. 11:((Suppl 2)):1990;S7.
14. Christensen E, Altman DG, Neuberger J, De Stavola BL, Tygstrup N, Williams R, PBC1 and PBC2 trial groups . Updating prognosis in primary biliary cirrhosis using a time-dependent Cox regression model. Gastroenterology 1993; 105: 1865-1876.
15. Murtaugh PA, Dickson ER, Van Dam GM, Malinchoe M, Grambsch PM, Langworthy AL, et al. Primary biliary cirrhosis: prediction of short-term survival based on repeated patient visits. Hepatology. 20:1994;126-134.
16. Hughes MD, Raskino CL, Pocock SJ, Biagini MR, Burroughs AK. Prediction of short-term survival with an application in primary biliary cirrhosis. Stat Med. 11:1992;1731-1745.
17. Neuberger J, Altman DG, Christensen E, Tygstrup N, Williams R. Use of a prognostic index in evaluation of liver transplantation for primary biliary cirrhosis. Transplantation. 41:1986;713-716.
18. Markus B, Dickson ER, Grambsch PM, Fleming TR, Mazzaferro V, Klintmalm GBG, et al. Efficacy of liver transplantation in patients with primary biliary cirrhosis. N Engl J Med. 320:1989;1709-1713.
19. Bonsel GJ, Klompmaker IJ, van't Veer F, Habbcma JD, Slooff MJ. Use of prognostic models for assessment of value of liver transplantation in primary biliary cirrhosis. Lancet. 335:1990;493-497.
20. Neuberger J, Altman DG, Polson R, Buckels J, Rolles K, Elias E, et al. Prognosis after liver transplantation for primary biliary cirrhosis. Transplantation. 48:1989;444-447.
21. Peto R, Pike MC, Armitage P, Breslow NE, Cox DR, Howard SV, et al. Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples. Br J Cancer. 35:1977;1-39.
22. Kaplan E, Meier P. Nonparametric estimation from incomplete observations. J Am Statist Assoc. 53:1958;457-481.
23. Cox DR. Regression models and life tables (with discussion). J R Statist Soc B. 34:1972;187-220.
24. Christensen E. Multivariate survival analysis using Cox's regression model. Hepatology. 7:1987;1346-1358.
25. Neuberger J, Christensen E, Portmann B, Caballeria J, Rodes J, Ranek L, et al. Double-blind controlled trial of d-penicillamine in patients with primary biliary cirrhosis. Gut. 26:1985;114-119.
26. Brown BW, Hollander M. Statistics. A Biomedical Introduction. 1977;317-324 Wiley, New York.
27. Gersovitz M, Munro HN, Udall J, Young VR. Albumin synthesis in young and elderly subjects using a new stable isotope methodology: response to level of protein intake. Metabolism. 29:1980;1075-1086.
28. Ricci P, Therneau TM, Malinchoc M, Benson JT, Petz JL, Klintmalm GB, et al. A prognostic model for the outcome of liver transplantation in patients with cholestatic liver disease. Hepatology. 25:1997;672-677.