Evaluation of the analgesic efficacy of EMLA cream in volunteers with differing skin pigmentation undergoing venipuncture

Regional Anesthesia and Pain Medicine

Volumn 24, Issue 2, 1999, Pages 165-169

  Riendeau, Lauren A ^a   Bennett, Donald ^a   Black Noller, Gillian ^a   Fan, Lisha ^a   Scavone, Joseph M ^a   Parmentier, James ^a  

^a Astra ZENECA Pharmaceuticals   (United States)

Author keywords

EMLA; Pigmentation; Skin; Topical anesthetic; Venipuncture

Indexed keywords

EMLA;

ADULT; ANALGESIA; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREAM; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG PENETRATION; DRUG SAFETY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PAIN; PRIORITY JOURNAL; SKIN IRRITATION; SKIN PIGMENTATION; TOPICAL ANESTHESIA; TOPICAL DRUG ADMINISTRATION; TREATMENT OUTCOME; VEIN PUNCTURE;

EID: 0032935777     PISSN: 0146521X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00115550-199924020-00012     Document Type: Article

References (17)

1. Hallen B, Carlsson P, Uppfeldt A. Clinical study of a lignocaine-prilocaine cream to relieve the pain of venepuncture. Br J Anaesth 1985: 57: 326-328.
2. de Waard-van der Spek FB, Mulder PGH, Oranje AP. Prilocaine/lidocaine patch as a local premedication for skin biopsy in children. J Am Acad Dermatol 1997: 37: 418-421.
3. de Waard-van der Spek FB, Oranje AP, Lillieborg S, Hop WCJ, Stolz E. Treatment of molluscum contagiosum using a lidocaine/prilocaine cream (EMLA) for analgesia. J Am Acad Dermatol 1990: 23: 685-688.
4. Hymes JA, Spraker MK. Racial differences in the effectiveness of a topically applied mixture of local anesthetics. Reg Anesth 1986: 11: 11-13.
5. Siddique NI, D'Alessio JG, Dmochowski RM. A comparative study of topical eutectic mixture of local anesthetics (EMLA) cream and dorsal nerve block for circumcision in adult males. Reg Anesth 1997: 22: 94.
6. Berardesca E, Maibach HI. Racial differences in percutaneous penetration of nicotinates in vivo in human skin: black and white. Acta Derm Venereol (Stockh) 1990: 70: 63-66.
7. Weigand DA, Gaylor JR. Irritant reaction in Negro and Caucasian skin. South Med J 1974: 67: 548-551.
8. Wedig JH, Maibach HI. Percutaneous penetration of dipyrithione in man: Effect of skin color (race). J Am Acad Dermatol 1981: 5: 433-438.
9. Berardesca E, de Rigal J, Leveque JL, Maibach HI. In vivo biophysical characterization of skin physiological differences in races. Dermatologica 1991: 182: 89-93.
10. Wilson D, Berardesca E, Maibach HI. In vitro transepidermal water loss: Differences between black and white human skin. Br J Dermatol 1988: 119: 647-652.
11. Weigand DA, Haygood C, Gaylor JR. Cell layers and density of negro and caucasian stratum corneum. J Invest Dermatol 1974: 62: 563-568.
12. McDonald CJ. Structure and function of the skin. Are there differences between black and white? Dermatol Clin 1988: 6: 343-347.
13. Melski JW, Tanenbaum L, Parrish JA, Fitzpatrick TB, Bleich HL. Oral methoxsalen photochemotherapy for the treatment of psoriasis: A cooperative clinical trial. J Invest Dermatol 1977: 68: 328-335.
14. Scott J, Huskisson EC. Graphic representation of pain. Pain 1976: 2: 177-184.
15. Joyce TH, Skjonsky BS, Taylor BD, Morrow DH, Hess KR. Dermal anesthesia using a eutectic mixture of lidocaine and prilocaine (EMLA) for venipuncture in children. Pain Digest 1992: 2: 137-141.
16. Hellgren U, Kihamia CM, Premji Z, Danielson K. Local anaesthetic cream for the alleviation of pain during venipuncture in Tanzanian school children. Br J Clin Pharm 1989: 28: 205-206.
17. Tan TO, Stafford TJ. EMLA for laser treatment of portwine stains in children. Lasers Surg Med 1992: 12: 543-548.