Inhibition of the production of endothelium-derived hyperpolarizing factor by cannabinoid receptor agonists

British Journal of Pharmacology

Volumn 126, Issue 4, 1999, Pages 949-960

  Fleming, I ^a   Schermer, B ^a   Popp, R ^a   Busse, R ^a  

^a UNIVERSITY HOSPITAL FRANKFURT   (Germany)

Author keywords

Cannabinoid CBI receptor; Electrophysiology; Endothelium derived hyperpolarizing factor (EDHF); Nitric oxide (NO)

Indexed keywords

ACETYLCHOLINE; ANANDAMIDE; BRADYKININ; CALCIUM ION; CANNABINOID RECEPTOR; CANNABINOID RECEPTOR AGONIST; CYTOCHROME P450; DEXANABINOL; DICLOFENAC; DRONABINOL; ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROSTAGLANDIN SYNTHASE; RIMONABANT;

ANIMAL TISSUE; ARTERY DILATATION; ARTERY MUSCLE; ARTERY TONE; ARTICLE; CAROTID ARTERY; CONTROLLED STUDY; CORONARY ARTERY; FEMALE; HUMAN; HUMAN CELL; HYPERPOLARIZATION; MALE; MESENTERIC ARTERY; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RABBIT; SWINE; VASCULAR ENDOTHELIUM;

EID: 0032935551     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702381     Document Type: Article

References (44)

1. BAUERSACHS, J., HECKER, M. & BUSSE, R. (1994). Display of the characteristics of endothelium-derived hyperpolarizing factor by a cytochrome P450-derived arachidonic acid metabolite in the coronary microcirculation. Br. J. Pharmacol.. 113, 1548-1553.
2. BAUERSACHS, J., POPP, R., HECKER, M., SAUER, E., FLEMING, I. & BUSSE, R. (1996). Nitric oxide attenuates the release of endothelium-derived hyperpolarizing factor. Circulation, 94, 3341-3347.
3. BERDYSHEV, E.V., BOICHOT, E. & LAGENTE, V. (1996). Anandamide - A new look on fatty acid ethanolamides. J. Lipid Mediators. Cell Signal., 15,49-67.
4. BORNHEIM, L.M., KIM, K.Y., CHEN, B. & CORREIA, M.A. (1993). The effect of cannabidiol on mouse hepatic microsomal cytochrome P450-dependent anandamide metabolism. Biochem. Biophys. Res. Commun., 197, 740-746.
5. BOUABOULA, M., PERRACHON, S., MILLIGAN, L., CANAT, X., RINALDI-CARMONA, M., PORTIER, M., EARTH, F., CALANDRA, B., PECCEU, F., LUPKER, J., MAFFRAND, J.-P., LE FUR, G. & CASELLAS, P. (1997). A selective inverse agonist for central cannabinoid receptor inhibits mitogen-activated protein kinase activation stimulated by insulin or insulin-like growth factor 1. J. Biol. Cliem., 272, 22330-22339.
6. CHATAIGNEAU, T., FELETOU, M., THOLLON, C., VILLENEUVE, N., VILAINE, J.P., DUHAULT, J. & VANHOUTTE, P.M. (1998). Cannabinoid CB1 receptor and endothelium-dependent hyperpolarization in guinea-pig carotid, rat mesenteric and porcine coronary arteries. Br. J. Pharmacol., 123, 968-974.
7. CHAYTOR, A.T., EVANS, W.H. & GRIFFITH, T.M. (1997). Peptides homologous to the extracellular loop motifs of connexin 43 reversibly abolish rhythmic contractile activity in rabbit arteries. J. Physiol. (Loud.), 503, 99-110.
8. GUILDERS, S.R., SEXTON, T. & ROY, M.B. (1994). Effects of anandamide on cannabinoid receptors in rat brain membranes. Biochem. Pharmacol., 47, 711-715.
9. DEUTSCH, D.G. & CHIN, S.A. (1993). Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist. Biochem. Pharmacol., 46, 791 - 796.
10. DEUTSCH, D.O., GOLIGORSKY, M.S., SCHMID, P.C., KREBSBACH, R.J., SCHMID, H.Ii., DAS, S.K., DEY, S.K., ARREAZA, G., THORUP, C, STEFANO, G. & MOORE, L.C. (1997). Production and physiological actions of anandamide in the vasculature of the rat kidney. J. Clin. In\est., 100, 1538-1546.
11. ELLIS, E.F., MOORE, S. & WILLOUGHBY, K.A. (1995). Anandamide and D9-THC dilation of cerebral arterioles is blocked by indomethacin. Am. J. Physiol., 269, H1859-H1864.
12. 9(11)-tetrahydrocannabinol and their interaction with norepinephrine. Life Sei.. 41, 79-87.
13. FACCI, L., DAL TOSO, R., ROMANELLO, S., BURIANI, A., SKAPER, S.D. & LEON, A. (1995). Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide. Proc. Nail. Acad. Sei. U.S.A. 92, 3376-3380.
14. 3 receptors in rat nodose ganglion neurones. J. Neurophysiol., 736, 907-910.
15. FELDER, C.C., BRILEY, E.M., AXELROD, J., SIMPSON, J.T., MACKIE, K. & DEVANE, W.A. (1993). Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction. Proc. Natl. Acad. Sei. U.S.A.. 90, 7656-7660.
16. FLEMING, L, FISSLTHALER, B. & BUSSE, R. (1995). Calcium signaling in endothelial cells involves activation of tyrosine kinases and leads to activation of MAP kinase. Circ. Res., 76, 522-529.
17. FLEMING, L, FISSLTHALER, B. & BUSSE, R. (1996). Interdependence of calcium signaling and protein tyrosine phosphorylation in human endothelial cells. J. Biol. Chem.. 271, 11009-11015.
18. GALIEGUE, S., MARY, S., MARCHAND, J., DUSSOSSOY, D., CARRIERE, D., CARAYON, P., BOUABOULA, M., SHIRE, D., LE FUR, G. & CASELLAS, P. (1995). Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations. Eitr. J. Biochem., 232, 54-61.
19. GRAHAM, J.D.P. & LI, D.M.F. (1973). Cardiovascular and respiratory effects of cannabis in cat and rat. Br. J. Pharmacol., 49, 1-10.
20. HOPKINS, N.K. & GORMAN, R.R. (1981). Regulation of endothelial cell cyclic nucleotide metabolism by prostacyclin. J. Clin. Invest., 67,540-546.
21. HUNTER, S.A. & BURSTEIN, S.H. (1997). Receptor mediation in cannabinoid stimulated arachidonic acid mobilization and anandamide synthesis. Life Sei., 60, 1563-1573.
22. KANEMITSU, M.Y. & LAU, A.F. (1993). Epidermal growth factor stimulates the disruption of gap junction communication and connexin43 phosphorylation independent of 12-O-tetradeacnoylphorbol 13-acetate-sensitive protein kinase C: the possible involvement of mitogen-activated protein kinase. Mol. Biol. Cell. 4, 827-848.
23. MOMBOULI, J.-V. & VANHOUTTE, P.M. (1997). Endothelium-derived hyperpolarizing factor(s): updating the unknown. Trends Pharmacol. Sei., 18, 252-256.
24. MUNRO, S., THOMAS, K.L. & ADU-SHAAR, M. (1993). Molecular characterization of a peripheral receptor for cannabinoid. Nature, 365, 61-65.
25. PERTWEE, R.G. (1997). Pharmacology of cannabinoid CB1 and CB2 receptors. Pharmacol. Ther., 74, 129-180.
26. PLANE, F., HOLLAND, M., WALDRON, G.J., GARLAND, C.J. & BOYLE, J.P. (1997). Evidence that anandamide and EDHF act via different mechanisms in rat isolated mesenteric arteries. Br. J. Pharmacol., 121, 1509-1512.
27. POPP, R., BAUERSACHS, J., HECKER, M., FLEMING, I. & BUSSE, R. (1996). A transferable, /î-naphthoflavone-inducible, hyperpolarizing factor is synthesised by native and cultured porcine coronary endothelial cells. J. Physiol. (Land.). 497.3, 699-709.
28. POPP, R., FLEMING, I. & BUSSE, R. (1998). Pulsatile stretch elicits the release of the endothelium-derived hyperpolarizing factor from isolated coronary arteries: a modulator of arterial compliance. Circ. Res., 81, 696-703.
29. POSTMA, F.R., HENGEVELD, T., ALBLAS, J., GIEPMANS, B.N., ZONDAG, G.C., JALINK, K. & MOOLENAAR, W.U. (1998). Acute loss of cell-cell communication caused by G protein-coupled receptors: A critical role for c-Src. J. Cell Biol., 140,1199-1209.
30. PRATT, P.P., HILLARD, C.J., EDGEMOND, W.S. & CAMPBELL, W.B. (1998). N-arachidonylethanolamide relaxation of bovine coronary artery is not mediated by CB1 cannabinoid receptor. Am. J. Physiol., 43, H375-H381.
31. PREVOT, V., RIALAS, CM., CROIX, D., SALZET, M., DUPOUY, J.P., POULAIN, P., BEAUVILLAIN, J.C. & STEFANO, G.B. (1998). Morphine and anandamide coupling to nitric oxide stimulates GnRH and CRF release from rat median eminence: neurovascular regulation. Brain Res., 790, 236-244.
32. QUILLEY, J., FULTON, D. & MCGIFF, J.C. (1997). Hyperpolarizing factors. Biochem. Pharmacol., 54, 1059-1070.
33. RANDALL, M.D., ALEXANDER, S.P.H., BENNETT, T., BOYD, E.A., FRY, J.R., GARDINER, S.M., KEMP, P.A., MCCULLOCH, A.I. & KENDALL, D.A. (1996). An endogenous cannabinoid as an endothelium-derived vasorelaxant. Biochem. Biophys. Res. Commun., 229, 114-120.
34. RANDALL, M.D. & KENDALL, D.A. (1997). Involvement of a cannabinoid in endothelium-derived hyperpolarizing factormediated coronary vasorelaxation. EUT. J. Pliarmacol., 335 205-209.
35. SATAKE, N., SHIBATA, M. & SHIBATA, S. (1997). Endothelium- and cytochrome P-450-dependent relaxation induced by isoproterenol in rat aortic rings. Eur. J. Pliarmacol., 319, 37-41.
36. SCHMILINSKY-FLURI, G., VALIUNAS, V., WILLI, M. & WEINGART, R. (1997). Modulation of cardiac gap junctions: the mode of action of arachidonic acid. J. Mol. Cell Cardiol., 29, 1703-1713
37. SHIRE, D., CARILLON, C., KAGHAD, M., CALANDRA, B., RINALDll CARMONA, M., LE FUR, G., CAPUT, D. & FERRARA, P. (1995). An amino-terminal variant of the central cannabinoid receptor resulting from alternative splicing. J. Biol. Chem., 270, 3726-3731.
38. SUGIURA, T., KODAKA, T., NAKANE, S., KISHIMOTO, S., KONDO, S. & WAKU, K. (1998). Detection of an endogenous cannabimimetic molecule, 2- arachidonoylglycerol, and cannabinoid CB1 receptor mRNA in human vascular cells: Is 2-arachidonoylglycerol a possible vasomodulator? Biochem. Biophys. Res Commun., 243, 838-843.
39. VARGA, K., LAKE, K., MARTIN, B.R. & KUNOS, G. (1995). Novel antagonist implicates the CB1 cannabinoid receptor in the hypotensive action of anandamide. Eur. J. Pliarmacol., 278, 279-283.
40. VENANCE, L., PIOMELLI, D., GLOWINSKI, J. & GIAUME, C. (1995). Inhibition by anandamide of gap junctions and intercellular calcium signaling in striatal astrocytes. Nature, 376, 590-594.
41. VIDRIO, H., SANCHEZ-SALVATORI, M.A. & MEDINA, M. (1996). Cardiovascular effects of (-)-H-O//-deIta8-tetrahydrocannabinol-dimethylheptyl in rats. J. Cardiovasc. Pliarmacol., 28, 332336.
42. VOGEL, Z., BARG, J., LEVY, R., SAYA, D., HELDMAN, E. & MECHOULAM, R. (1993). Anandamide, a brain endogenous compound, interacts specifically with cannabinoid receptors and inhibits adenylate cyclase. J. Neurochem., 61, 352-355.
43. WARTMANN, M., CAMPBELL, D., SUBRAMANIAN, A., BURSTEIN, S.U. & DA VIS, R.J. (1995). The MAP kinase signal transduction pathway is activated by the endogenous cannabinoid anandamide. FEES Lett., 359, 133-136.
44. YATOMI, Y., OZAKI, Y. & KUME, S. (1992). Synthesis of phosphatidylinositol 3,4-bisphosphate but not phosphatidylinositol 1,3,5-trisphosphate is closely correlated with protein tyrosine phosphorylation in thrombin-activated human platelets. Biochem. Biophys. Res. Commun., 186, 1480-1486.