Diagnostic relevance of chromosomal in-situ hybridization in Merkel cell carcinoma: Targeted interphase cytogenetic tumour analyses

Histopathology

Volumn 34, Issue 2, 1999, Pages 163-169

  Amo Takyi, B K ^a   Tietze, L ^b   Tory, K ^b   Guerreiro, P ^b   Gunther K ^b   Bhardwaj, R S ^b   Mittermayer, C ^b   Handt, S ^b  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b NONE

Author keywords

Immunohistochemistry; Interphase cytogenetics; Merkel cell carcinoma; Mutation analysis; Small cell lung carcinoma

Indexed keywords

ADULT; ARTICLE; CASE REPORT; CYTOGENETICS; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LUNG CANCER; LUNG NON SMALL CELL CANCER; MALE; MERKEL CELL TUMOR; NEUROENDOCRINE TUMOR; PRIORITY JOURNAL; X CHROMOSOME;

ADULT; CARCINOMA, MERKEL CELL; CHROMOSOMES, HUMAN; GENES, P53; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INTERPHASE; MALE; SCALP; SEX CHROMOSOMES; SKIN NEOPLASMS;

EID: 0032934712     PISSN: 03090167     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2559.1999.00580.x     Document Type: Article

References (48)

1. Agnarsson BA, Vonderheid EC, Kadin ME. Cutaneous T cell lymphoma with suppressor/cytotoxic (CD 8) phenotype: identification of rapidly progressive and chronic subtypes. J. Am. Acad. Dermatol. 1990; 22; 569-77.
2. Bielamowicz S, Smith D, Abemayor E. Merkel cell carcinoma: an aggressive skin neoplasm. Laryngoscope 1994: 104; 528-532.
3. Raaf JH, Uhrmacher C, Knapper WK, Shiu, MH, Cheng EWK. Trabecular (Merkel cell) carcinoma of the skin. Treatment of primary, recurrent and metastatic disease. Cancer 1986; 57; 178-182.
4. Toker C. Trabecular carcinoma of the skin. Arch. Dermatol. 1972; 105; 107-110.
5. LeBoit PE, Crutcher WA, Shapiro PE. Pagetoid intraepidermal spread in Merkel cell (primary neuroendocrine) carcinoma of the skin. Am. J. Surg. Pathol. 1992; 16; 584-592.
6. Dunker H, Eggers G, Löffler K. Neuroendokrines Karzinom der Haut (Merkelzellkarzinom) im Kindesalter. Pathologe 1988; 9; 370-374.
7. Gherardi G, Marveggio C, Stiglich F. Parotid metastasis of Merkel cell carcinoma in a young patient with ectodermal dysplasia. Diagnosis by fine needle aspiration cytology and immunocytochemistry. Acta Cytol. 1990; 34; 831-836.
8. Schmid CH, Beham A, Feichtinger J, Auböck L, Dietze O. Recurrent and subsequently metastasizing Merkel cell carcinoma in a 7-year-old girl. Histopathology 1992; 20; 437-439.
9. Pitale M, Sessions R, Husain S. An analysis of prognostic factors in cutaneous neuroendocrine carcinoma. Laryngoscope 1992; 102; 244-249.
10. Rice RD Jr, Chonkich GD, Thompson KS, Chase DR. Merkel cell tumor of the head and neck. Five new cases with literature review. Arch. Otolaryngol. Head Neck Surg. 1993; 119; 782-786.
11. Leff EL, Brooks JSJ, Trojanowski JQ. Expression of neurofilament and neuron-specific enolase in small cell tumors of skin using immunohistochemistry. Cancer 1985; 56; 625-636.
12. Areas A, Bescos S, Hueto JA, Raspall G. Merkel cell tumor. Report of case. J. Oral Maxillofac. Surg. 1995; 53; 1200-1203.
13. Frigerio B, Capella C, Eusebi V, Tenti P, Azzopardi JG. Merkel cell carcinoma of the skin: the structure and origin of normal Merkel cells. Histopathology 1983; 7; 229-249.
14. Kayashima K, Ono T, Johno M, Kojo Y, Yamashita N, Matsunaga W. Spontaneous regression in Merkel cell (neuroendocrine) carcinoma of the skin. Arch. Dermatol. 1991; Apr: 127; 550-553.
15. Shaw J, Rumball E. Merkel cell tumour: Clinical behaviour and treatment. Br. J. Surg. 1991; 78; 138-142.
16. Tennvall J, Bjorklund A, Johansson L, Akerman M. Merkel cell carcinoma: Management of primary, recurrent and metastatic disease. A clinicopathological study of 17 patients. Eur. J. Surg. Oncol. 1989; 15; 1-9.
17. Warner TFCS, Uno H, Hafez GR et al. Merkel cell and Merkel cell tumours. Ultrastructure, immunocytochemistry and review of the literature. Cancer 1983; 52; 238-245.
18. Vortmeyer AO, Merino MJ, Böni R, Liotta LA, Cavazzana A, Zhuang Z. Genetic changes associated with primary Merkel cell carcinoma. Am. J. Clin. Pathol. 1998; 109; 565-570.
19. Gibas Z, Well S, Chen ST, McCue PA. Deletion of chromosome arm 1p in a Merkel cell carcinoma (MCC). Genes Chromosom. Cancer 1994; 9; 216-220.
20. Harle M, Arens N, Moll I, Back W, Schulz T, Scherthan H. Comparative genomic hybridization (CGH) discloses chromosomal and subchromosomal copy number changes in Merkel cell carcinomas. J. Cutan. Pathol. 1996; 23; 391-7.
21. Leonard JH, Leonard P, Kearsley JH. Chromosomes 1, 11, and 13 are frequently involved in karyotypic abnormalities in metastatic Merkel cell carcinoma. Cancer Genet. Cytogenet. 1993; 67; 65-70.
22. Perlman EJ, Hawkins AL, Griffin CA. Primary cutaneous carcinoma (Merkel cell carcinoma): cytogenetic and MIC2 analysis (abstract). Cancer Genet. Cytogenet. 1993; 66; 153.
23. Ronan SG, Green AD, Shilkaitis A, Huang TW, Das Gupta TK. Merkel cell carcinoma: in vitro and in vivo characteristics of a new cell line. J. Am. Acad. Dermatol. 1993; 29; 715-722.
24. Sozzi G, Bertoglio MG, Pilotti S. Rilke F, Pierotti MA, Della Porta GD. Cytogenetic studies in primary, and metastatic neuroendocrine Merkel cell carcinoma. Cancer Genet. Cytogenet. 1988; 30; 151-158.
25. Larsimont D, Verhest A. Chromosome 6 trisomy as sole anomaly in a primary Merkel cell carcinoma. Virchows Arch. 1996; 428; 305-309.
26. Sandbrink F, Muller L, Fiebig HH, Kovács G. Deletion 7q, trisomy 6 and 11 in a case of Merkel cell carcinoma. Cancer Genet. Cytogenet. 1988; 33; 305-309.
27. Amo-Takyi BK, Handt S, Gunawan B, Hollweg H-G, Füzesi L. A cytogenetic approach to the differential diagnosis of metastatic clear cell renal carcinoma. Histopathology 1998; 32; 436-443.
28. Kovach JS, McGovern BM, Cassady JD et al. Direct sequencing from touch preparations of human carcinomas: analysis of p53 mutations in breast carcinomas. J. Natl. Cancer Inst. 1991; 83; 1004-1009.
29. Sommer SS, Cunningham J, McGovern RM et al. Pattern of p53 mutations in breast cancers of the Midwestern United States. J. Natl. Cancer Inst. 1992; 84; 246-252.
30. Bortolani A, Barisoni D, Colombari R, Furlan S. Merkel-cell carcinoma of the skin. Plast-Reconstr-Surg. 1992; Apr: 89; 751-754.
31. Maurer J, Busch M, Matthaei D, Bergholz M, Halling F, Duhmke E. Case reports on the importance of the locoregional radiotherapy of Merkel cell tumor. Strahlenther-Onkol. 1992; 168; 536-40.
32. Meeuwissen JA, Bourne RG, Kearsley JH. The importance of postoperative radiation therapy in the treatment of Merkel cell carcinoma. Int. J. Radiat. Oncol. Biol. Phys. 1995; 31; 325-31.
33. Smith DE, Bielamowicz S, Kagan AR, Anderson PJ, Peddada AV. Cutaneous neuroendocrine (Merkel cell) carcinoma. A report of 35 eases. Am. J. Clin. Oncol. 1995; 18; 199-203.
34. Suntharalingam M, Rudoltz MS, Mendenhall WM, Parsons JT, Stringer SP, Million RR. Radiotherapy for Merkel cell carcinoma of the skin of the head and neck. Head Neck 1995; 17; 96-101.
35. Sheppard MN, Corrin B, Bennett MH, Marangos PJ, Bloom SR, Polak JM. Immunocytochemical localization of neuron-specific enolase in small cell carcinomas and carcinoid tumours of the lung. Histopathology 1984; 8; 171-181.
36. Van Muijen GNP, Ruiter DJ, van Leeuwen C, Prins FA, Rietsema K, Warnaar SO. Cytokeratin and neurofilament in lung carcinomas. Am. J. Pathol. 1984; 116; 363-369.
37. Bensch KG, Corrin B, Pariente R, Spencer H. Oat-cell carcinoma of the lung. Its origin and relationship to bronchial carcinoid. Cancer 1968; 22; 1163-1172.
38. Elema JD, Keuning HM. The ultrastructure of small cell lung carcinoma in bronchial biopsy specimens. Hum. Pathol. 1985; 16; 1133-1140.
39. Sibley RK, Rosai J, Foucar E, Dehner LP, Bost G. Neuroendocrine (Merkel cell) carcinoma of the skin. A histologic and ultrastructural study, of two cases. Am. J. Surg. Pathol. 1980; 4; 211-221.
40. Eusebi V, Capella C, Cossu A, Rosai J. Neuroendocrine carcinoma within lymph nodes in the absence of a primary tumor, with special reference to Merkel cell carcinoma. Am. J. Surg. Pathol. 1992; 16; 658-666.
41. Naylor SL, Johnson BE, Minna JD, Sakaguchi AY. Loss of heterozygosity of chromosome 3p markers in small-cell lung cancer. Nature 1987; 329; 451-454.
42. Whang-Peng J. 3p Deletion and small cell lung carcinoma. Mayo Clin. Proc. 1989; 64; 256-260.
43. Drabkin HA, Mendez MJ, Rabbitts PH et al. Characterization of the submicroscopic deletion in the small cell lung carcinoma (SCLC) cell line U2020. Genes Chromosom. Cancer 1992; 5; 67-74.
44. Hurr K, Kemp B, Silver SA, El-Naggar AK. Microsatellite alteration at chromosome 3p loci in neuroendocrine and non-neuroendocrine lung tumors. Histogenetic and clinical relevance. Am. J. Pathol. 1996; 149; 613-620.
45. Testa JR, Graziano SL. Molecular implications of recurrent cytogenetic alterations in human small cell lung cancer. Cancer Detect. Prev. 1993; 17; 267-277.
46. Sozzi G, Alder H, Tornielli S et al. Aberrant FHIT transcripts in Merkel cell carcinoma. Cancer Res. 1996; 56; 2472-4.
47. Shlegelberger B, Bartels H, Sterry W. Chromosomal evolution in a Merkel cell carcinoma. Cancer Genet. Cytogenet. 1994; 75; 74-76.
48. Enzinger FM, Weiss SW eds. Primitive neuroectodermal tumors and related lesions. In Soft tissue tumors. 3rd edn. St Louis, Missouri: CV Mosby, 1995; 929-964.