Selective 1,4-reduction of α,β-unsaturated carbonyl compounds by combined use of bis(1,3-diketonato)cobalt(II) complex and diisobutylaluminum hydride

Synlett

Volumn , Issue 1, 1999, Pages 96-98

  Ikeno, Taketo ^a   Kimura, Tomomi ^a   Ohtsuka, Yuhki ^a   Yamada, Tohru ^a  

^a KEIO UNIVERSITY   (Japan)

Author keywords

1,4 reduction; Bis(acetylacetonato)cobalt(II) complex; Cobalt hydride; Diisobutylaluminum hydride; , unsaturated carbonyl compound

Indexed keywords

ALUMINUM DERIVATIVE; CARBONYL DERIVATIVE; COBALT COMPLEX;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; ORGANIC CHEMISTRY; REACTION ANALYSIS; REDUCTION; SYNTHESIS;

EID: 0032934386     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1999-2557     Document Type: Article

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22. 3 and brine, then dried over anhydrous sodium sulfate. After evaporation of the solvents, the crude product was purified by silica gel column chromatography to give ethyl octanoate (85.8 mg, 99.5% yield).
23. Since the reactions proceed more slowly for congested substrates, part of the cobalt hydride species could be decomposed.