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Volumn 35, Issue 6, 1999, Pages 554-563

Assessment of the U.S. Environmental Protection Agency methods for identification of hazards to developing organisms, part II: The Developmental Toxicity Testing Guideline

Author keywords

Chemical safety; Developmental toxicity; Environmental health policy; Environmental pollutants; Environmental protection agency; Environmental regulation; Industrial chemicals; Pesticides; Prenatal development; Toxicity testing

Indexed keywords

ARTICLE; EMBRYO CULTURE; ENVIRONMENTAL PROTECTION; FETUS DISEASE; FOOD SAFETY; HAZARD; HUMAN; NONHUMAN; PRENATAL DEVELOPMENT; PRENATAL EXPOSURE; TOXICITY TESTING; UNITED STATES;

EID: 0032934224     PISSN: 02713586     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0274(199906)35:6<554::AID-AJIM2>3.0.CO;2-X     Document Type: Article
Times cited : (16)

References (66)
  • 1
    • 0029005384 scopus 로고
    • Validation of an in vitro teratology system using chiral substances: Stereoselective teratogenicity of 4-n-valproic acid in cultured mouse embryos
    • Andrews JE, Ebron-McCoy M, Bojic U, Nau H, Kavlock RJ. 1995. Validation of an in vitro teratology system using chiral substances: stereoselective teratogenicity of 4-n-valproic acid in cultured mouse embryos. Toxicol Appl Pharmacol 132:310-316.
    • (1995) Toxicol Appl Pharmacol , vol.132 , pp. 310-316
    • Andrews, J.E.1    Ebron-McCoy, M.2    Bojic, U.3    Nau, H.4    Kavlock, R.J.5
  • 2
    • 0030748961 scopus 로고    scopus 로고
    • Stereoselective dysmorphogenicity of the enantiomers of the valproic acid analog 2-N-propyl-4-pentynoic acid (4-yn-VPA): Cross-species evaluation in whole embryo culture
    • Andrews JE, Ebron-McCoy MT, Bojic U, Nau H. Kavlock RJ. 1997. Stereoselective dysmorphogenicity of the enantiomers of the valproic acid analog 2-N-propyl-4-pentynoic acid (4-yn-VPA): cross-species evaluation in whole embryo culture. Teratology 55:314-318.
    • (1997) Teratology , vol.55 , pp. 314-318
    • Andrews, J.E.1    Ebron-McCoy, M.T.2    Bojic, U.3    Nau, H.4    Kavlock, R.J.5
  • 5
    • 0014485109 scopus 로고
    • A rapid method for detecting malformations in rat fetuses
    • Barrow MV, Taylor WJ. 1969. A rapid method for detecting malformations in rat fetuses. J Morphol 127:291-306.
    • (1969) J Morphol , vol.127 , pp. 291-306
    • Barrow, M.V.1    Taylor, W.J.2
  • 6
    • 0019434249 scopus 로고
    • Assessment of adult skeletons to detect prenatal exposure to 2,4,5.-T or trifluralin in mice
    • Beck SL. 1981. Assessment of adult skeletons to detect prenatal exposure to 2,4,5.-T or trifluralin in mice. Teratology 23:33-55.
    • (1981) Teratology , vol.23 , pp. 33-55
    • Beck, S.L.1
  • 7
    • 0028304841 scopus 로고
    • Lethality, teratogenicity and growth inhibition of heptanol in Xenopus assayed by a modified frog embryo teratogenesis assay-Xenopus (FETAX) procedure
    • Bernardini G, Vismara C, Boracchi P, Camatini M. 1994. Lethality, teratogenicity and growth inhibition of heptanol in Xenopus assayed by a modified frog embryo teratogenesis assay-Xenopus (FETAX) procedure. Sci Total Environ 151:1-8.
    • (1994) Sci Total Environ , vol.151 , pp. 1-8
    • Bernardini, G.1    Vismara, C.2    Boracchi, P.3    Camatini, M.4
  • 8
    • 0029864856 scopus 로고    scopus 로고
    • Identification of proximate toxicant for ethylene glycol developmental toxicity using rat whole embryo culture
    • Carney EW, Liberack AB, Bartels MJ, Breslin WJ. 1996. Identification of proximate toxicant for ethylene glycol developmental toxicity using rat whole embryo culture. Teratology 53:38-46.
    • (1996) Teratology , vol.53 , pp. 38-46
    • Carney, E.W.1    Liberack, A.B.2    Bartels, M.J.3    Breslin, W.J.4
  • 9
    • 77957181276 scopus 로고
    • Evaluation of chick embryo neural retinal cell culture as a screen for developmental toxicants
    • Daston GP, Baines D, Elmore E, Fitzgerald MP, Sharma S. 1995. Evaluation of chick embryo neural retinal cell culture as a screen for developmental toxicants. Fund Appl Toxocil 26:203-210.
    • (1995) Fund Appl Toxocil , vol.26 , pp. 203-210
    • Daston, G.P.1    Baines, D.2    Elmore, E.3    Fitzgerald, M.P.4    Sharma, S.5
  • 10
    • 0001372178 scopus 로고
    • Guidelines for the health assessment of suspect developmental toxicants
    • Environmental Protection Agency. 1986. Guidelines for the health assessment of suspect developmental toxicants. Federal Register 51:34028-34040.
    • (1986) Federal Register , vol.51 , pp. 34028-34040
  • 13
    • 0021288290 scopus 로고
    • Differentiation of rat embryo cells in culture: Response following acute maternal exposure to teratogens and non-teratogens
    • Flint OP, Orton TC, Ferguson RA. 1984. Differentiation of rat embryo cells in culture: response following acute maternal exposure to teratogens and non-teratogens. J Appl Toxicol 4:109-116.
    • (1984) J Appl Toxicol , vol.4 , pp. 109-116
    • Flint, O.P.1    Orton, T.C.2    Ferguson, R.A.3
  • 14
    • 0027157139 scopus 로고
    • Evaluation of the developmental toxicity of trichloroethylene and detoxification metabolites using Xenopus
    • Fort DJ, Stover EL, Rayburn JR, Hull M, Bantle JA. 1993. Evaluation of the developmental toxicity of trichloroethylene and detoxification metabolites using Xenopus. Teratog Carcinog Mutagen 13:35-45.
    • (1993) Teratog Carcinog Mutagen , vol.13 , pp. 35-45
    • Fort, D.J.1    Stover, E.L.2    Rayburn, J.R.3    Hull, M.4    Bantle, J.A.5
  • 15
    • 0030447131 scopus 로고    scopus 로고
    • Evaluation of the developmental toxicity of theophylline, dimethylumeri acid, and methylxanthine metabolites using Xenopus
    • Fort DJ, Stover EL, Propst T, Hull MA, Bantle. 1996a. Evaluation of the developmental toxicity of theophylline, dimethylumeri acid, and methylxanthine metabolites using Xenopus. Drug Chem Toxicol 19:267-278.
    • (1996) Drug Chem Toxicol , vol.19 , pp. 267-278
    • Fort, D.J.1    Stover, E.L.2    Propst, T.3    Hull, M.A.4    Bantle5
  • 16
    • 0030427696 scopus 로고    scopus 로고
    • Evaluation of the developmental toxicity of 4-bromobenzene using frog embryo teratogenesis assay, Xenopus: Possible mechanisms of action
    • Fort DJ, Propst TL, Stover EL. 1996b. Evaluation of the developmental toxicity of 4-bromobenzene using frog embryo teratogenesis assay, Xenopus: possible mechanisms of action. Teratog Carcinog Mutagen 16:307-315.
    • (1996) Teratog Carcinog Mutagen , vol.16 , pp. 307-315
    • Fort, D.J.1    Propst, T.L.2    Stover, E.L.3
  • 17
    • 0030447528 scopus 로고    scopus 로고
    • Paternal exposures: Impact on reproductive and developmental outcome. An overview
    • Friedler G. 1996. Paternal exposures: impact on reproductive and developmental outcome. An overview. Pharmacol Biochem Behav 55:691-700.
    • (1996) Pharmacol Biochem Behav , vol.55 , pp. 691-700
    • Friedler, G.1
  • 18
    • 0014869192 scopus 로고
    • Ossification of the rat and mouse skeleton in the perinatal period
    • Fritz H, Hess R. 1970. Ossification of the rat and mouse skeleton in the perinatal period. Teratology 3:331-338.
    • (1970) Teratology , vol.3 , pp. 331-338
    • Fritz, H.1    Hess, R.2
  • 19
    • 0031952568 scopus 로고    scopus 로고
    • Occupational exposure to pesticides and congenital malformations: A review of mechanisms, methods, and results
    • Garcia AM. 1998. Occupational exposure to pesticides and congenital malformations: a review of mechanisms, methods, and results. Am J Ind Med 33:232-240.
    • (1998) Am J Ind Med , vol.33 , pp. 232-240
    • Garcia, A.M.1
  • 20
    • 0028991114 scopus 로고
    • Assessment of developmental toxicity potential of chemicals by quantitative structure-toxicity relationship models
    • Gombar VK, Enslein K, Blake BW. 1995. Assessment of developmental toxicity potential of chemicals by quantitative structure-toxicity relationship models. Chemosphere 31:2499-2510.
    • (1995) Chemosphere , vol.31 , pp. 2499-2510
    • Gombar, V.K.1    Enslein, K.2    Blake, B.W.3
  • 21
    • 0030056459 scopus 로고    scopus 로고
    • Kids are different: Developmental variability in toxicology
    • Graeter LJ, Mortensen ME. 1996. Kids are different: developmental variability in toxicology. Toxicology 111:15-20.
    • (1996) Toxicology , vol.111 , pp. 15-20
    • Graeter, L.J.1    Mortensen, M.E.2
  • 22
    • 0016591370 scopus 로고
    • The neurotoxic effects of triethyltin sulfate on myelinating cultures of mouse spinal cord
    • Graham DI, Kim SU, Gonatas NK, Guyotte L. 1975. The neurotoxic effects of triethyltin sulfate on myelinating cultures of mouse spinal cord. J Neuropathol Exp Neurol 34:401-412.
    • (1975) J Neuropathol Exp Neurol , vol.34 , pp. 401-412
    • Graham, D.I.1    Kim, S.U.2    Gonatas, N.K.3    Guyotte, L.4
  • 23
    • 0028670684 scopus 로고
    • Neural cell targets of human immunodeficiency virus type 1 in human fetal organotypic cultures
    • Hatch WC, Pousada E, Losev L, Rashbaum WK, Lyman WD. 1994. Neural cell targets of human immunodeficiency virus type 1 in human fetal organotypic cultures. AIDS Res Hum. Retroviruses 10:1597-1601.
    • (1994) AIDS Res Hum. Retroviruses , vol.10 , pp. 1597-1601
    • Hatch, W.C.1    Pousada, E.2    Losev, L.3    Rashbaum, W.K.4    Lyman, W.D.5
  • 24
    • 0344486502 scopus 로고
    • Frequency of spontaneous axial skeletal variations detected by the double staining technique for ossified and cartilaginous skeleton in rat fetuses
    • Igarashi E, Kawamura N, Okumura H, Hotta K, Okamoto T, Inaoke M, Takeshita S, Yasuda M. 1992. Frequency of spontaneous axial skeletal variations detected by the double staining technique for ossified and cartilaginous skeleton in rat fetuses. Cong Anom 32:381-391.
    • (1992) Cong Anom , vol.32 , pp. 381-391
    • Igarashi, E.1    Kawamura, N.2    Okumura, H.3    Hotta, K.4    Okamoto, T.5    Inaoke, M.6    Takeshita, S.7    Yasuda, M.8
  • 25
    • 0344486503 scopus 로고
    • Chronic oral toxicity of chlordane to rats
    • Ingle L. 1952. Chronic oral toxicity of chlordane to rats. AMA Arch Ind Hyg 6:357-367.
    • (1952) AMA Arch Ind Hyg , vol.6 , pp. 357-367
    • Ingle, L.1
  • 26
    • 0024421780 scopus 로고
    • Prediction of risk for human developmental toxicity: How important are animal studies for hazard identification?
    • Jelovsek FR, Mattison DR, Chen JJ. 1989. Prediction of risk for human developmental toxicity: How important are animal studies for hazard identification? Obstet Gynecol 74:624-636.
    • (1989) Obstet Gynecol , vol.74 , pp. 624-636
    • Jelovsek, F.R.1    Mattison, D.R.2    Chen, J.J.3
  • 27
    • 0025105192 scopus 로고
    • Structure-activity relationships in the developmental toxicity of substituted phenols: In vivo effects
    • Kavlock RJ. 1990. Structure-activity relationships in the developmental toxicity of substituted phenols: in vivo effects. Teratology 41:43-59.
    • (1990) Teratology , vol.41 , pp. 43-59
    • Kavlock, R.J.1
  • 28
    • 0027353745 scopus 로고
    • Structure-activity approaches in the screening of environmental agents for developmental toxicity
    • Kavlock RJ. 1993. Structure-activity approaches in the screening of environmental agents for developmental toxicity. Reprod Toxicol 7:113-116.
    • (1993) Reprod Toxicol , vol.7 , pp. 113-116
    • Kavlock, R.J.1
  • 29
    • 0026380430 scopus 로고
    • In vivo and in vitro structure-dosimetry-activity relationships of substituted phenols in developmental toxicity assays
    • Kavlock RJ, Oglesby LA, Hall LL, Fisher HL, Copeland F, Logsdon T, Ebron-McCoy M. 1991. In vivo and in vitro structure-dosimetry-activity relationships of substituted phenols in developmental toxicity assays. Reprod Toxicol 5:255-258.
    • (1991) Reprod Toxicol , vol.5 , pp. 255-258
    • Kavlock, R.J.1    Oglesby, L.A.2    Hall, L.L.3    Fisher, H.L.4    Copeland, F.5    Logsdon, T.6    Ebron-McCoy, M.7
  • 30
    • 77957185882 scopus 로고
    • Developmental toxicity of N-methyl-formamide administered by gavage to CD rats and New Zealand White rabbits
    • Kelich SL, Mead PL, Seyler DE. 1995. Developmental toxicity of N-methyl-formamide administered by gavage to CD rats and New Zealand White rabbits. Fund Appl Toxicol 27:239-246.
    • (1995) Fund Appl Toxicol 27:239-246.
    • Kelich, S.L.1    Mead, P.L.2    Seyler, D.E.3
  • 31
    • 0015725907 scopus 로고
    • Skeletal deviations in rats: Malformations or variations?
    • Kimmel CA, Wilson JG. 1973. Skeletal deviations in rats: malformations or variations? Teratology 8:309-316.
    • (1973) Teratology , vol.8 , pp. 309-316
    • Kimmel, C.A.1    Wilson, J.G.2
  • 33
    • 0026702831 scopus 로고
    • Developmental stages of the CD (Sprague-Dawley) rat skeleton after maternal exposure to ethylene glycol
    • Marr MC, Price CJ, Myers CB, Morrissey RE. 1992. Developmental stages of the CD (Sprague-Dawley) rat skeleton after maternal exposure to ethylene glycol. Teratology 46:69-181.
    • (1992) Teratology , vol.46 , pp. 69-181
    • Marr, M.C.1    Price, C.J.2    Myers, C.B.3    Morrissey, R.E.4
  • 34
    • 0014203087 scopus 로고
    • On reproduction studies and the occurrence of cataracts in rats after long-term feeding of the insecticide heptachlor
    • Mestitzova M. 1967. On reproduction studies and the occurrence of cataracts in rats after long-term feeding of the insecticide heptachlor. Experientia 23:42-43.
    • (1967) Experientia , vol.23 , pp. 42-43
    • Mestitzova, M.1
  • 35
    • 0344917706 scopus 로고
    • Dissection procedure for rat fetuses permitting alizarin red staining of skeleton and histological study of viscera
    • Monie IW, Kho KG, Morgan. 1965. Dissection procedure for rat fetuses permitting alizarin red staining of skeleton and histological study of viscera. Supplemental Teratology Workshop Manual, p 163-173.
    • (1965) Supplemental Teratology Workshop Manual , pp. 163-173
    • Monie, I.W.1    Kho, K.G.2    Morgan3
  • 37
    • 0029046057 scopus 로고
    • A multidisciplinary approach to toxicological screening: II. Developmental toxicity
    • Narotsky MG, Kavlock RJ. 1995. A multidisciplinary approach to toxicological screening: II. Developmental toxicity. J Toxicol Environ Health 45:145-171.
    • (1995) J Toxicol Environ Health , vol.45 , pp. 145-171
    • Narotsky, M.G.1    Kavlock, R.J.2
  • 38
    • 0031472066 scopus 로고    scopus 로고
    • Critical period of carbon tetrachloride-induced pregnancy loss in Fischer-344 rats, with insights into the detection of resorption sites by ammonium sulfide staining
    • Narotsky MG, Brownie CF, Kavlock RJ. 1997. Critical period of carbon tetrachloride-induced pregnancy loss in Fischer-344 rats, with insights into the detection of resorption sites by ammonium sulfide staining. Teratology 56:252-261.
    • (1997) Teratology , vol.56 , pp. 252-261
    • Narotsky, M.G.1    Brownie, C.F.2    Kavlock, R.J.3
  • 39
    • 0003655906 scopus 로고
    • Committee on Pesticides in the Diets of Infants and Children. Washington, DC: National Academy Press
    • National Research Council. 1993. Pesticides in the Diets of Infants and Children. Committee on Pesticides in the Diets of Infants and Children. Washington, DC: National Academy Press. p 146.
    • (1993) Pesticides in the Diets of Infants and Children , pp. 146
  • 40
    • 0018052913 scopus 로고
    • Statistical analysis of teratologic data: Problems and advancements
    • Nelson CJ, Holson JF. 1978. Statistical analysis of teratologic data: problems and advancements. J Environ Pathol Toxicol 2:187-199.
    • (1978) J Environ Pathol Toxicol , vol.2 , pp. 187-199
    • Nelson, C.J.1    Holson, J.F.2
  • 41
    • 0027635817 scopus 로고
    • Assessment of the effectiveness of animal developmental toxicity testing for human safety
    • Newman LM, Johnson EM, Staples RE. 1993. Assessment of the effectiveness of animal developmental toxicity testing for human safety. Reprod Toxicol 7:359-390.
    • (1993) Reprod Toxicol , vol.7 , pp. 359-390
    • Newman, L.M.1    Johnson, E.M.2    Staples, R.E.3
  • 42
    • 0026513235 scopus 로고
    • In vitro embryotoxicity of a series of para-substituted phenols: Structure, activity and correlation with in vivo data
    • Oglesby LA, Ebron-McCoy M, Logsdon T, Copeland F, Beyer PE, Kavlock RJ. 1992. In vitro embryotoxicity of a series of para-substituted phenols: structure, activity and correlation with in vivo data. Teratology 45:11-33.
    • (1992) Teratology , vol.45 , pp. 11-33
    • Oglesby, L.A.1    Ebron-McCoy, M.2    Logsdon, T.3    Copeland, F.4    Beyer, P.E.5    Kavlock, R.J.6
  • 43
    • 0028792638 scopus 로고
    • In vitro murine embryotoxicity of cyclophosphamide in embryos co-cultured with maternal hepatocytes: Development and application of a murine embryo-hepatocyte co-culture model
    • Ozolins TR, Oglesby LA, Wiley MJ, Wells PG. 1995. In vitro murine embryotoxicity of cyclophosphamide in embryos co-cultured with maternal hepatocytes: development and application of a murine embryo-hepatocyte co-culture model. Toxicology 102:259-274.
    • (1995) Toxicology , vol.102 , pp. 259-274
    • Ozolins, T.R.1    Oglesby, L.A.2    Wiley, M.J.3    Wells, P.G.4
  • 44
    • 0031062303 scopus 로고    scopus 로고
    • Multiple factors contribute to the toxicity of the aromatic retinoid, TTNPB (Ro 13-7410): Binding affinities and disposition
    • Pignatello MA, Kauffman FC, Levin AA. 1997. Multiple factors contribute to the toxicity of the aromatic retinoid, TTNPB (Ro 13-7410): binding affinities and disposition. Toxicol Appl Pharmacol 142:319-327.
    • (1997) Toxicol Appl Pharmacol , vol.142 , pp. 319-327
    • Pignatello, M.A.1    Kauffman, F.C.2    Levin, A.A.3
  • 46
    • 0024311320 scopus 로고
    • Limb bud cell culture for in vitro teratogen screening: Validation of an improved assessment method using 51 compounds
    • Renault JY, Melcion C, Cordier A. 1989. Limb bud cell culture for in vitro teratogen screening: validation of an improved assessment method using 51 compounds. Teratog Carcinog Mutagen 9:83-96.
    • (1989) Teratog Carcinog Mutagen , vol.9 , pp. 83-96
    • Renault, J.Y.1    Melcion, C.2    Cordier, A.3
  • 47
    • 0029810590 scopus 로고    scopus 로고
    • Pollutants in breast milk
    • Rogan WJ. 1996. Pollutants in breast milk. Arch Pediatr Adolesc Med 150:981-990.
    • (1996) Arch Pediatr Adolesc Med , vol.150 , pp. 981-990
    • Rogan, W.J.1
  • 49
    • 0029621915 scopus 로고
    • Developmental toxicity of trichloroethylene, tetrachloroethylene and four of their metabolites in rat whole embryo culture
    • Saillenfait AM, Langonne I, Sabate JP. 1995. Developmental toxicity of trichloroethylene, tetrachloroethylene and four of their metabolites in rat whole embryo culture. Arch Toxicol 70:71-82.
    • (1995) Arch Toxicol , vol.70 , pp. 71-82
    • Saillenfait, A.M.1    Langonne, I.2    Sabate, J.P.3
  • 51
    • 0024574088 scopus 로고
    • Potential human developmental toxicants and the role of animal testing in their identification and characterization
    • Schardein JL, Keller KA. 1989. Potential human developmental toxicants and the role of animal testing in their identification and characterization. CRC Crit Rev Toxicol 19:251-339.
    • (1989) CRC Crit Rev Toxicol , vol.19 , pp. 251-339
    • Schardein, J.L.1    Keller, K.A.2
  • 54
    • 0001030345 scopus 로고
    • The order and time of appearance of center of ossification in the fore and hind limbs of the albino rat, with special reference to the possible influence of the sex factor
    • Spark C, Dawson AB. 1928. The order and time of appearance of center of ossification in the fore and hind limbs of the albino rat, with special reference to the possible influence of the sex factor. Am J Anat 41:411-445.
    • (1928) Am J Anat , vol.41 , pp. 411-445
    • Spark, C.1    Dawson, A.B.2
  • 55
    • 0015782610 scopus 로고
    • Effects of thallium on neuronal mitochondria in organotypic cord-ganglion-muscle combination cultures
    • Spencer PS, Peterson ER, Madrid R, Raine CS. 1973. Effects of thallium on neuronal mitochondria in organotypic cord-ganglion-muscle combination cultures. J Cell Biol 58:79-91.
    • (1973) J Cell Biol , vol.58 , pp. 79-91
    • Spencer, P.S.1    Peterson, E.R.2    Madrid, R.3    Raine, C.S.4
  • 56
    • 0001396471 scopus 로고
    • The order, time, and rate of ossification of the albino rat (Mus norvegicus albinus) skeleton
    • Strong RM. 1928. The order, time, and rate of ossification of the albino rat (Mus norvegicus albinus) skeleton. Am J Anat 36:313-355.
    • (1928) Am J Anat , vol.36 , pp. 313-355
    • Strong, R.M.1
  • 57
    • 0028040044 scopus 로고
    • NGF increases neuritic complexity of cholinergic interneurons in organotypic cultures of neonatal rat striatum
    • Studer L, Spenger C , Luthman J, Seiler RW. 1994. NGF increases neuritic complexity of cholinergic interneurons in organotypic cultures of neonatal rat striatum. J Comp Neurol 340:281-301.
    • (1994) J Comp Neurol , vol.340 , pp. 281-301
    • Studer, L.1    Spenger, C.2    Luthman, J.3    Seiler, R.W.4
  • 59
    • 0029583352 scopus 로고
    • Comparison of two approaches to analyzing correlated binary data in developmental toxicity studies
    • Ten-Have TR, Hartzel T. 1995. Comparison of two approaches to analyzing correlated binary data in developmental toxicity studies. Teratology 52:267-276.
    • (1995) Teratology , vol.52 , pp. 267-276
    • Ten-Have, T.R.1    Hartzel, T.2
  • 60
    • 0024314963 scopus 로고
    • Toxic effects of organophosphates on nerve cell growth and ultrastructure in culture
    • Tuler SM, Bowen JM. 1989. Toxic effects of organophosphates on nerve cell growth and ultrastructure in culture. J Toxicol Environ Health 27:209-220.
    • (1989) J Toxicol Environ Health , vol.27 , pp. 209-220
    • Tuler, S.M.1    Bowen, J.M.2
  • 61
    • 0030453756 scopus 로고    scopus 로고
    • Relation of TGF-beta 2 to inhibition of limb bud chondrogenesis by retinoid in rats
    • Tsuiki H, Fukiishi Y, Kishi K. 1996. Relation of TGF-beta 2 to inhibition of limb bud chondrogenesis by retinoid in rats. Teratology 54:191-197.
    • (1996) Teratology , vol.54 , pp. 191-197
    • Tsuiki, H.1    Fukiishi, Y.2    Kishi, K.3
  • 62
    • 8044246984 scopus 로고
    • A tissue-culture model of methyl n-butyl ketone neuropathy in organotypic tissue culture
    • Spencer PS, Schaumburg HH, editors. Baltimore: Williams and Wilkins Press
    • Veronesi B, Peterson ER, Spencer PS. 1980. A tissue-culture model of methyl n-butyl ketone neuropathy in organotypic tissue culture. In: Spencer PS, Schaumburg HH, editors. Experimental and clinical neurotoxicology. Baltimore: Williams and Wilkins Press. p 863.
    • (1980) Experimental and Clinical Neurotoxicology , pp. 863
    • Veronesi, B.1    Peterson, E.R.2    Spencer, P.S.3
  • 63
    • 0030971749 scopus 로고    scopus 로고
    • A review of the contribution of whole embryo culture to the determination of hazard and risk in teratogenicity testing
    • Webster WS, Brown-Woodman PD, Ritchie HE. 1997. A review of the contribution of whole embryo culture to the determination of hazard and risk in teratogenicity testing. Int J Dev Biol 41:329-335.
    • (1997) Int J Dev Biol , vol.41 , pp. 329-335
    • Webster, W.S.1    Brown-Woodman, P.D.2    Ritchie, H.E.3
  • 64
    • 0023090629 scopus 로고
    • A comparison of developmental toxicity evident at term to postnatal growth and survival using ethylene glycol monoethyleter, ethylene glycol monobutyl ether, and ethanol
    • Weir PJ, Lewis SC, Traul KA. 1987. A comparison of developmental toxicity evident at term to postnatal growth and survival using ethylene glycol monoethyleter, ethylene glycol monobutyl ether, and ethanol. Teratog Carcinog Mutagen 7:55-64.
    • (1987) Teratog Carcinog Mutagen , vol.7 , pp. 55-64
    • Weir, P.J.1    Lewis, S.C.2    Traul, K.A.3
  • 65
    • 17644443755 scopus 로고
    • Methods and concepts in detecting abnormal reproductive outcomes of paternal origin
    • Wyrobek AJ. 1993. Methods and concepts in detecting abnormal reproductive outcomes of paternal origin. Reprod Toxicol 7(Suppl 1):3-16.
    • (1993) Reprod Toxicol , vol.7 , Issue.SUPPL. 1 , pp. 3-16
    • Wyrobek, A.J.1
  • 66
    • 0029038844 scopus 로고
    • Lamina-specific expression of adhesion molecules in developing chick optic tectum
    • Yamagata M, Herman JP, Sanes J R. 1995. Lamina-specific expression of adhesion molecules in developing chick optic tectum. J Neurosci 15:4556-4565.
    • (1995) J Neurosci , vol.15 , pp. 4556-4565
    • Yamagata, M.1    Herman, J.P.2    Sanes, J.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.