Development and standardization of methods to evaluate the antibody response to an HIV-1 candidate vaccine in secretions and sera of seronegative vaccine recipients

Journal of Immunological Methods

Volumn 222, Issue 1-2, 1999, Pages 111-124

  Raux, M ^a   Finkielsztejn, L ^b   Salmon Ceron D ^b   Bouchez, H ^b   Excler, J L ^c   Dulioust, E ^b   Grouin, J M ^d   Sicard, D ^b   Blondeau, C ^a  

^a Clinical Sero Immunology Laboratory   (France)

^b Hôpital Cochin ^*  (France)

^c Pasteur Merieux Connaught   (France)

^d NONE

Author keywords

ELISA; gp120 MN; HIV 1; IgA; IgG; Mucosal immunity; p24 LAI

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS VACCINE;

ANTIBODY BLOOD LEVEL; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; PRIORITY JOURNAL; SERODIAGNOSIS;

AIDS VACCINES; BODY FLUIDS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE PRODUCTS, GAG; HIV ANTIBODIES; HIV ENVELOPE PROTEIN GP120; HIV SERONEGATIVITY; HIV-1; HUMANS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; LINEAR MODELS; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SALIVA; SENSITIVITY AND SPECIFICITY; SERUM ALBUMIN;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0032932919     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-1759(98)00188-4     Document Type: Article

References (35)

1. Archibald D.W., Barr C.E., Torosian J.P., McLane M.F., Essex M. Secretory IgA antibodies to human immunodeficiency virus in the parotid saliva of patients with AIDS and AIDS related complex. J. Infect. Dis. 155:1987;793-796.
2. Archibald D.W., Herbert C.A., Sun D., Tacket C.O. Salivary antibodies to human immunodeficiency virus type 1 in a phase I AIDS vaccine trial. J. AIDS. 3:1990;954-958.
3. Artenstein A.W., VanCott T.C., Sitz K.V., Robb M.L., Wagner K.F., Veit S., Garner R., Byron J., Burnett P., Birx D. Mucosal immune responses in four distinct compartments of women infected with human immunodeficiency virus type 1: a comparison by site and correlation with clinical information. J. Infect. Dis. 175:1997;265-271.
4. Behets F.M., Edidi B., Quinn T.C., Atikala L., Bishagaral K., Nzila N., Laga M., Piot P., Ryder R.W., Brown C.C. Detection of salivary HIV-1 specific IgG antibodies in high risk populations in Zaïre. J. AIDS. 4:1991;183-187.
5. Bélec L., Dupré T., Prazuck T., Tévi-Benissan C. Kanga J.M., Pathey O., Lu X.S., Pillot J. Cervico-vaginal overproduction of specific IgG to human immunodeficiency virus (HIV) contrasts with normal or impaired IgA local response in HIV infection. J. Infect. Dis. 172:1995;691-697.
6. Bélec L., Meillet D., Levy M., Georges A.J., Tévi-Benissan C., Pillot J. Dilution assessment of cervico-vaginal secretions obtained by vaginal washing for immunological assays. Clin. Diagn. Lab. Immunol. 2:1995;57-61.
7. Bélec L., Tévi-Benissan C., Lu X.S., Prazuck T., Pillot J. Local synthesis of IgG antibodies to HIV within the female and male genital tracts during asymptomatic and pre-AIDS stages of HIV infection. AIDS Res. Hum. Retrovirus. 11:1995;719-729.
8. Connel J.A., Parry J.V., Mortimer P.P., Duncam J. Novel assay for the detection of immunoglobulin G anti-human immunodeficiency virus in untreated saliva and urine. J. Med. Virol. 41:1993;159-164.
9. Essex M. Retroviral vaccines: challenge for the developing world. AIDS Res. Hum. Retrovirus. 12:1996;361-363.
10. Funkhouser A., Clements M.L., Slome S., Clayman B., Viscidi R. Antibodies to recombinant gp160 in mucosal secretions and sera of persons infected with HIV-1 and seronegative vaccine recipients. AIDS Res. Hum. Retrovirus. 7:1993;627-632.
11. NIAID AIDS Vaccine Clinical Trials Network, Gorse G.J., Rogers J.H., Perry J.E., Newman F.K., Frey S.E., Patel G.B., Belshe R.B. HIV-1 recombinant gp160 vaccine antibodies in serum and saliva. Vaccine. 2:1995;209-214.
12. Haimovici F., Mayer K.H., Anderson D.J. Quantitation of HIV-1 specific IgG, IgA and IgM antibodies in human genital tract secretions. J. AIDS Hum. Retrovirus. 15:1997;185-191.
13. Iscaki S., Bouvet J.P. Human secretory immunoglobulin A and its role in mucosal defence. Bull. Inst. Pasteur. 91:1993;203-224.
14. Jonard P.P., Rambaud J.C., Dive C., Vaerman J.P., Gallan A., Delacroix D.L. Secretions of immunoglobulins and plasma proteins from the jejunal mucosa. Transport rate and origin of polymeric immunoglobulin A. J. Clin. Invest. 74:1984;525-535.
15. Kozlowski P.A., Jackson S. Serum IgA subclasses and molecular forms in HIV infection: selective increases in monomer and apparent restriction of the antibody response to IgA1 antibodies directed at env glycoproteins. AIDS Res. Hum. Retrovirus. 10:1992;1773-1780.
16. NIAID-sponsored AIDS Vaccine Evaluation, Lambert J.S., Viscidi R., Wlker M.C., Clayman B., Winget M., Wolff M., Schwartz D.H. Antibody to human immunodeficiency virus type 1 (HIV-1) gp160 in mucosal specimens of asymptomatic HIV-1 infected volunteers parenterally immunized with an experimental recombinant HIV-1 IIIB gp160 vaccine. Clin. Diagn. Lab. Immunol. 3:1997;302-308.
17. Lü X.S., Bélec L., Pillot J. Anti-gp160 IgG and IgA antibodies associated with a large increase in total IgG cervico-vaginal secretions from human immunodeficiency virus type 1-infected women. J. Infect. Dis. 167:1993;1189-1192.
18. Lü, X.S., Grangeot-Keros, Blot, A., Rannou, M.T., Delfraissy, J.F., Pillot, J., 1993b. Comparison of saliva and serum for HIV antibody testing. IX International Conference on AIDS, Berlin, June 7-11, Abstract PO-B40-2457.
19. Lü X.S., Delfraissy J.F., Grangeot-Keros L., Rannou M.T., Pillot J. Rapid and constant detection of HIV antibody response in saliva of HIV infected patients: selective distribution of anti-HIV activity in the IgG isotype. Res. Virol. 145:1994;369-377.
20. Mann, J.M., 1992. AIDS - the second decade: a global perspective. J. Infect. Dis. 165-245.
21. McGhee J.R., Mestecky J., Derzbaugh M.T., Eldridge J.H., Hirasawa M., Kiyono H. The mucosal immune system: from fundamental concepts to vaccine development. Vaccine. 10:1992;75-88.
22. Matsuda S., Oka S., Honda M., Takebe Y., Takemori T. Characteristics of IgA antibodies against HIV-1 in sera and saliva from HIV-seropositive individuals in different clinical stages. Scand. J. Immunol. 38:1993;428-434.
23. Mazanec M.B., Nedrud J.G., Kaetzel C.S., Lamm M.E. A three-tiered view of the role of IgA in mucosal defence. Immunol. Today. 14:1993;430-435.
24. Mestecky J., Jackson S. Reassessment of the impact of mucosal immunity in infection with the human immunodeficiency virus (HIV) and design of relevant vaccines. J. Clin. Immunol. 14:1994;259-272.
25. Milman G., Sharma O. Mechanisms of HIV/SIV mucosal transmission. AIDS Res. Hum. Retrovirus. 10:1994;1305-1312.
26. Mohamed O.A., Ashley R., Goldstein A., McElrath J., Dalessio J., Corey L. Detection of rectal antibodies to HIV-1 by a sensitive chemoluminescent Western blot immunodetection method. J. AIDS. 7:1994;375-380.
27. Moore J., Wallace L., Follett E., McKeating J. An enzyme-linked immunosorbent assay for antibodies to the envelope glycoproteins of divergent strains of HIV-1. AIDS. 3:1989;155-163.
28. Mostad S.B., Kreiss J.K. Shedding of HIV-1 in the genital tract. AIDS. 10:1996;1305-1315.
29. Nakane P.K., Kawaoi A. Peroxidase labelled antibody, a new method of conjugation. J. Histochem. Cytochem. 22:1974;1084-1091.
30. Schaefer M.E., Rhodes M., Prince S., Michalek S.M., McGree J.R. A plastic intraoral device for the collection of human parotid saliva. J. Dent. Res. 56:1977;728-733.
31. Stefanache-Guichard A.I. HIV vaccine and genital secretory immune response. Rom. J. Virol. 46(1-2):1995;85-98.
32. Sweet S.P., Rahman D., Challacombe J. Serum and saliva immunoglobulin A concentrations shows an inverse relationship in HIV infection and AIDS. AIDS. 9:1995;1288-1289.
33. Sweet S.P., Rahman D., Challacombe J. IgA subclasses in HIV disease; dichotomy between raised levels in serum and decreased secretion rates in saliva. Immunology. 86:1995;556-559.
34. Underdown B.J., Schiff J.M. Immunoglobulin A: strategic defence initiative at the mucosal surface. Annu. Rev. Immunol. 4:1986;389-417.
35. Vasudevachari M.B., Uffelman K.W., Kovacs J., Yeh C., Lane H.C., Salzman N.P. Envelope-specific antibodies in the saliva of individuals vaccinated with recombinant HIV-1 gp160. J. AIDS. 5:1992;817-821.