The interdomain linker of Escherichia coli initiation factor IF3: A possible trigger of translation initiation specificity

Molecular Microbiology

Volumn 32, Issue 1, 1999, Pages 193-202

  De Cock, Eve ^a,b   Springer, Mathias ^c   Dardel, Frédéric ^a  

^a LABORATOIRE DE BIOCHIMIE   (France)

^b LABORATOIRE DE SYNTHÈSE ORGANIQUE   (France)

^c INST DE BIOLOGIE PHYSICO CHIMIQUE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

INITIATION FACTOR 3; RIBOSOME RNA; TRANSFER RNA;

ARTICLE; CHEMICAL COMPOSITION; CODON; COVALENT BOND; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; RIBOSOME SUBUNIT; SITE DIRECTED MUTAGENESIS; TRANSLATION INITIATION;

ESCHERICHIA COLI; NEGIBACTERIA; PROKARYOTA;

EID: 0032932835     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.1999.01350.x     Document Type: Article

References (40)

1. Biou, V., Shu, F., and Ramakrishnan, V. (1995) X-ray crystallography shows that translational initiation factor IF3 consists of two compact alpha/beta domains linked by an alpha-helix. EMBO J 14: 4056-4064.
2. Boileau, G., Butler, P., Hershey, J.W., and Traut, R.R. (1983) Direct cross-links between initiation factors 1, 2, and 3 and ribosomal proteins promoted by 2-iminothiolane. Biochemistry 22: 3162-3170.
3. Brombach, M., and Pon, C.L. (1987) The unusual translational initiation codon AUU limits the expression of the infC (initiation factor IF3) gene of Escherichia coli. Mol Gen Genet 208: 94-100.
4. Bruhns, J., and Gualerzi, C. (1980) Structure-function relationships in Escherichia coli initiation factors: role of tyrosine residues in ribosomal binding and functional activity of IF3. Biochemistry 19: 1670-1676.
5. Butler, J.S., Springer, M., Dondon, J., Graffe, M., and Grunberg-Manago, M. (1986) Escherichia coli protein synthesis initiation factor IF3 controls its own gene expression at the translational level In vivo. J Mol Biol 192: 767-780.
6. Butler, J.S., Springer, M., and Grunberg-Manago, M. (1987) AUU-to-AUG mutation in the initiator codon of the translation initiation factor IF3 abolishes translational autocontrol of its own gene (infC) in vivo. Proc Natl Acad Sci USA 84: 4022-4025.
7. Cooperman, B.S., Expert-Bezancon, A., Kahan, L., Dondon, J., and Grunberg-Manago, M. (1981) IF-3 crosslinking to Escherichia coli ribosomal 30S subunits by three different light-dependent procedures: identification of 30S proteins crosslinked to IF-3 - utilization of a new two-stage cross-linking reagent, p-nitrobenzylmaleimide. Arch Biochem Biophys 208: 554-562.
8. Ehresmann, C., Moine, H., Mougel, M., Dondon, J., Grunberg-Manago, M., Ebel, J.P., et al. (1986) Cross-linking of initiation factor IF3 to Escherichia coli 30S ribosomal subunit by trans-diamminedichloroplatinum (II): characterization of two cross-linking sites in 16S rRNA; a possible way of functioning for IF3. Nucleic Acids Res 14: 4803-4821.
9. Fortier, P.L., Schmitter, J.M., Garcia, C., and Dardel, F. (1994) The N-terminal half of initiation factor IF3 is folded as a stable independent domain. Biochimie 76: 376-383.
10. 15N resonance assignments and structure of the N-terminal domain of Escherichia coli initiation factor 3. Eur J Biochem 228: 395-402.
11. Garcia, C., Fortier, P.L., Blanquet, S., Lallemand, J.Y., and Dardel, F. (1995b) Solution structure of the ribosome-binding domain of E. coli translation initiation factor IF3. Homology with the U1A protein of the eukaryotic spliceosome. purification/metabolism. J Mol Biol 254: 247-259.
12. Gold, L., Stormo, G., and Saunders, R. (1984) Escherichia coli translational initiation factor IF3: a unique case of translational regulation. Proc Natl Acad Sci USA 81: 7061-7065.
13. Gualerzi, C.O., and Pon, C.L. (1990) Initiation of mRNA translation in prokaryotes. Biochemistry 29: 5883-5889.
14. Gualerzi, C., Pon, C.L., and Kaji, A. (1971) Initiation factor dependent release of aminoacyl-tRNAs from complexes of 30S ribosomal subunits, synthetic polynucleotides and aminoacyl-tRNA. Biochem Biophys Res Commun 45: 1312-1319.
15. Hamilton, C.M., Aldea, M., Washburn, B.K., Babitzke, P., and Kushner, S.R. (1989) New method for generating deletions and gene replacements in Escherichia coli. J Bacteriol 171:4617-4622.
16. Hartz, D., Binkley, J., Hollingsworth, T., and Gold, L. (1990) Domains of initiator tRNA and initiation codon crucial for initiator tRNA selection by Escherichia coli IF3. Genes Dev 4: 1790-1800.
17. Heimark, R.L., Kahan, L., Johnston, K., Hershey, J.W., and Traut, R.R. (1976) Cross-linking of initiation factor IF3 to proteins of the Escherichia coli 30S ribosomal subunit. J Mol Biol 105: 219-230.
18. Hoffman, D.W., Davies, C., Gerchlan, S.E., Kycia, J.H., Porter, S.J., White, S.W., et al. (1994) Crystal structure of prokaryotic ribosomal protein L9: a bi-lobed RNA binding protein. EMBO J 13: 205-212.
19. Hua, Y., and Raleigh, D.P. (1998) On the global architecture of initiation factor IF3: a comparative study of the linker regions from the Escherichia coli protein and the Bacillus stearothermophilus protein. J Mol Biol 278: 871-878.
20. Kycia, J.H., Biou, V., Shu, F., Gerchman, S.E., Graziano, V., and Ramakrishnan, V. (1995) Prokaryotic translation initiation factor IF3 is an elongated protein consisting of two crystallizable domains. Biochemistry 34: 6183-6187.
21. Lammi, M., Pon, C.L., and Gualerzi, C.O. (1987) The NH2-terminal cleavage of Escherichia coli translational initiation factor IF3. A mechanism to control the intracellular level of the factor? FEBS Lett 215: 115-121.
22. Lillemoen, J., Cameron, C.S., and Hoffman, D.W. (1997) The stability and dynamics of ribosomal protein L9: investigations of a molecular strut by amide proton exchange and circular dichroism. J Mol Biol 268: 482-493.
23. MacKeen, L.A., Kahan, L., Wahba, A.J., and Schwartz, I. (1980) Photochemical cross-linking of initiation factor-3 to Escherichia coli 30S ribosomal subunits. J Biol Chem 255: 10526-10531.
24. Maitra, U., Stringer, E.A., and Chandhuri, A. (1982) Initiation factors in protein biosynthesis. Annu Rev Biochem 51: 869-900.
25. 1H spin-spin coupling constants in proteins. Biochem Biophys Res Commun 113: 964-974.
26. Meinnel, T., Mechulam, Y., and Fayat, G. (1988) Fast purification of a functional elongator tRNAmet expressed from a synthetic gene in vivo. Nucleic Acids Res 16: 8095-8096.
27. Moazed, D., Samaha, R.R., Gualerzi, C., and Noller, H.F. (1995) Specific protection of 16S RNA by translational initiation factors. J Mol Biol 248: 207-210.
28. Moreau, M., de Cock, E., Fortier, P.L., Garcia, C., Albaret, C., Blanquet, S., et al. (1997) Heteronuclear NMR studies of E. coli translation initiation factor IF3. Evidence that the inter-domain region is disordered in solution. J Mol Biol 266: 15-22.
29. Muralikrishna, P., and Wickstrom, E. (1989) Escherichia coli initiation factor 3 protein binding to 30S ribosomal sub-units alters the accessibility of nucleotides within the conserved central region of 16S rRNA. Biochemistry 28: 7505-7510.
30. Plumbridge, J.A., Springer, M., Graffe, M., Goursot, R., and Grunberg-Manago, M. (1980) Physical localisation and cloning of the structural gene for E. coli initiation factor IF3 from a group of genes concerned with translation. Gene 11: 33-42.
31. Pon, C., Cannistraro, S., Giovane, A., and Gualerzi, C. (1982a) Structure-function relationship in Escherichia coli initiation factors. Environment of the Cys residue and evidence for a hydrophobic region in initiation factor IF3 by fluorescence and ESR spectroscopy. Arch Biochem Biophys 217: 47-57.
32. Pon, C.L., and Gualerzi, C. (1976) The role of 16S rRNA in ribosomal binding of IF3. Biochemistry 15: 804-811.
33. Pon, C.L., Pawlik, R.T., and Gualerzi, C. (1982b) The topographical localization of IF3 on Escherichia coli 30S ribosomal subunits as a clue to its way of functioning. FEBS Lett 137: 163-167.
34. Risuleo, G., Gualerzi, C., and Pon, C.L. (1976) Specificity and properties of the destabilization induced by initiation factor IF3 of ternary complexes of 30S ribosomal subunits, aminoacyl-tRNA and polynucleotides. Eur J Biochem 67: 603-613.
35. Sacerdot, C., Fayat, G., Dessen, P., Springer, M., Plumbridge, J.A., Grunberg-Manago, M., et al. (1982) Sequence of a 1.26 kb DNA fragment containing the structural gene for E. coli initiation factor IF3: presence of an AUU initiator codon. EMBO J 1:311-315.
36. Sacerdot, C., Chiaruttini, C., Engst, K., Graffe, M., Milet, M., Mathy, N., et al. (1996) The role of the AUU initiation codon in the negative feedback regulation of the gene for translation initiation factor IF3 in Escherichia coli. Mol Microbiol 21: 331-346.
37. Subramanian, A.R., and Davis, B.D. (1970) Activity of initiation factor 3 in dissociating Escherichia ribosomes. Nature 228: 1273-1275.
38. Sussman, J.K., Simons, E.L., and Simons, R.W. (1996) Escherichia coli translation initiation factor 3 discriminates the initiation codon in vivo. Mol Microbiol 21: 347-360.
39. Tapprich, W.E., Goss, D.J., and Dahlberg, A.E. (1989) Mutation at position 791 in Escherichia coli 16S ribosomal RNA affects processes involved in the initiation of protein synthesis. Proc Natl Acad Sci USA 86: 4927-4931.
40. Yu, N.J., and Spremulli, L.L. (1997) Structural and mechanistic studies on chloroplast translational initiation factor 3 from Euglena gracilis. Biochemistry 36: 14827-14835.