Evaluation of mitoxantrone-loaded albumin microspheres following intraperitoneal administration to rats

Journal of Controlled Release

Volumn 57, Issue 1, 1999, Pages 35-44

  Luftensteiner, C P ^a   Schwendenwein, I ^a   Paul, B ^a   Eichler, H G ^a   Viernstein, H ^a  

^a UNIVERSITY OF VIENNA   (Austria)

Author keywords

Albumin microspheres; In vivo; Intraperitoneal chemotherapy; Mitoxantrone; Sustained release

Indexed keywords

ALBUMIN; GLUTARALDEHYDE; MICROSPHERE; MITOXANTRONE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; CROSS LINKING; DEGRADATION; DRUG BLOOD LEVEL; FEMALE; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; PARTICLE SIZE; PHARMACOKINETICS; PRIORITY JOURNAL; SUSTAINED DRUG RELEASE;

ALBUMINS; ANALGESICS; ANIMALS; AREA UNDER CURVE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; GLUTARAL; INJECTIONS, INTRAPERITONEAL; MALE; MICROSPHERES; MITOXANTRONE; PARTICLE SIZE; RATS; RATS, SPRAGUE-DAWLEY; SOLUTIONS;

EID: 0032932512     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(98)00098-4     Document Type: Article

References (27)

1. Knüsli C., Ruff P., Laffer U.et al. Intraperitoneal chemotherapy in peritoneal malignancy: impact of intensive system care on practicability. Acta Med. Austriaca. 16(3/4):1989;70-73.
2. Blöchl-Daum B., Eichler H.G., Rainer H.et al. Escalating dose regimen of intraperitoneal mitoxantrone: phase I study - clinical and pharmacokinetic evaluation. Eur. J. Cancer Clin. Oncol. 24(7):1988;1133-1138.
3. Lorusso V., Catino A., Gargano G., Fioretto A., Berardi F., De Lena M. Mitoxantrone in the treatment of recurrent ascites of pretreated ovarian carcinoma. Eur. J. Gynaec. Oncol. 15(1):1994;75-80.
4. Maiche A.G. Management of peritoneal effusions with intracavitary mitoxantrone or bleomycin. Anti-Cancer Drugs. 5:1994;305-308.
5. Markman M., Reichman B., Hakes T.et al. Intraperitoneal chemotherapy in the management of ovarian cancer. Cancer. 71(4):1993;1565-1570.
6. Müller B.G., Leuenberger H., Kissel T. Albumin nanospheres as carriers for passive drug targeting: an optimized manufacturing technique. Pharm. Res. 13(1):1996;32-37.
7. Longo W.E., Iwata H., Lindheimer T.A., Goldberg E.P. Preparation of hydrophilic albumin microspheres using polymeric dispersing agents. J. Pharm. Sci. 71(12):1982;1323-1328.
8. Law S.L., Jang T.F. High-performance liquid chromatographic determination of mitoxantrone in liposome preparations using solid-phase extraction and its application in stability studies. J. Chromatogr. A 670:1994;234-238.
9. Priston M.J., Sewell G.J. Improved LC assay for the determination of mitozantrone in plasma: analytical considerations. J. Pharm. Biomed. Anal. 12(9):1994;1153-1162.
10. Griffini A., Vandelli M.A., Seghizzi R., Mucci A., Pfifferi G. Pharmaceutical evaluation of gelatin microspheres crosslinked with D,L-glyceraldehyde. Determinations of residuals of the preparation procedure. Pharm. Pharmacol. Lett. 6(1):1996;16-18.
11. Menet M.C., Gueylard D., Fievet M.H., Thuillier A. Fast specific separation and sensitive quantification of bactericidal and sporicidal aldehydes by high-performance liquid chromatography: example of glutaraldehyde determination. J. Chromatogr. B 692:1996;79-86.
12. W.R. Chappell, J. Mordenti, Extrapolation of toxicological and pharmacological data from animals to humans, in: B. Testa (Ed.), Advances in Drug Research, Vol. 20, Academic Press, London, 1991, pp. 1-116.
13. Catalin J., Peloux A.F., Coloma F., Payet B., Lacarelle B., Cano J.P. Direct determination of mitoxantrone in plasma by high performance liquid chromatography using an automatic precolumn-switching system as sample clean-up procedure. Biomed. Chromatogr. 8:1994;37-41.
14. Slørdal L., Andersen A., Warren D.J. A sensitive and simple high-performance liquid chromatographic method for the determination of mitoxantrone in plasma. Ther. Drug Monit. 15(4):1993;328-333.
15. Ehninger G., Schuler U., Proksch B., Zeller K.P., Blanz J. Pharmacokinetics and metabolism of mitoxantrone - a review. Clin. Pharmacokinet. 18(5):1990;365-380.
16. Alberts D.S., Young L., Mason N., Salmon S.E. In vitro evaluation of anticancer drugs against ovarian cancer at concentrations achievable by intraperitoneal administration. Semin. Oncol. 12(3(Suppl. 4)):1985;38-42.
17. Hagiwara A., Takahashi T., Kojima O.et al. Prophylaxis with carbon-adsorbed mitomycin against peritoneal recurrence of gastric cancer. Lancet. 339:1992;629-631.
18. Hagiwara A., Takahashi T., Kojima O.et al. Pharmacologic effects of cisplatin microspheres on peritoneal carcinomatosis in rodents. Cancer. 71(3):1993;844-850.
19. Lee J.S., Takahashi T., Hagiwara A.et al. Safety and efficacy of intraperitoneal injection of etoposide in oil suspension in mice with peritoneal carcinomatosis. Cancer Chemother. Pharmacol. 36:1995;211-216.
20. Demetrick J.S., Liggins R.T., Machan L., Davis N.L., Burt H.M., Hunter W.L. The development of a novel intraperitoneal tumor-seeding prophylactic. Am. J. Surg. 173:1997;403-406.
21. Batra V.K., Morrison J.A., Woodward D.L., Siverd N.S., Yacobi A. Pharmacokinetics of mitoxantrone in man and laboratory animals. Drug Metab. Rev. 17(3/4):1986;311-329.
22. Gupta P.K., Hung C.T. Albumin microspheres I: physico-chemical characteristics. J. Microencapsulation. 6(4):1989;427-462.
23. J. Ugelstad, A. Rembaum, J.T. Kemshead, K. Nustad, S. Funderud, R. Schmid, Preparation and biomedical applications of monodisperse polymer particles, in: S.S. Davis, L. Illum, J.G. McVie, E. Tomlinson (Eds.), Microspheres and Drug Therapy: Pharmaceutical, Immunological and Medical Aspects, Elsevier, Amsterdam, 1984, pp. 365-382.
24. Negrini D., Mukenge S., Del Fabbro M., Gonano C., Miserocchi G. Distribution of diaphragmatic lymphatic stomata. J. Appl. Physiol. 70(4):1991;1544-1549.
25. Markman M., Alberts D., Rubin S.et al. Evidence for persistence of mitoxantrone within the peritoneal cavity following intraperitoneal delivery. Gynecol. Oncol. 48:1993;185-188.
26. Faulds D., Balfour J.A., Chrisp P., Langtry H.D. Mitoxantrone - a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in the chemotherapy of cancer. Drugs. 41(3):1991;400-449.
27. Witowski J., Breborowicz A., Knapowski J. Effect of methotrexate, doxorubicin and mitoxantrone on human peritoneal mesothelial cell function in vitro. Oncology. 52:1995;60-65.