Differential regulation of c-fos expression in estrogen-induced hamster renal tumors compared with kidney not due to creation of an estrogen- response element by point mutation in the gene's flanking sequence

Molecular Carcinogenesis

Volumn 24, Issue 4, 1999, Pages 255-262

  Sarabia, Stephen F ^a,b   Liehr, Joachim G ^a,c  

^a University of Texas Medical Branch School of Medicine   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Stehlin Found for Cancer Research   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ALPHA NAPHTHOFLAVONE; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR; FREE RADICAL; MESSENGER RNA; PALINDROMIC DNA;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; DNA FLANKING REGION; DNA POLYMORPHISM; DNA SEQUENCE; ESTROGEN ACTIVITY; GENE EXPRESSION REGULATION; GENE ISOLATION; GENE SEQUENCE; KIDNEY TUMOR; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE C FOS; POINT MUTATION; PRIORITY JOURNAL; PROTO ONCOGENE; SEQUENCE ANALYSIS; SUBCUTANEOUS DRUG ADMINISTRATION; SYRIAN HAMSTER;

ANIMALS; BASE SEQUENCE; CRICETINAE; CRICETULUS; DNA, NEOPLASM; ESTRADIOL; GENES, FOS; KIDNEY; KIDNEY NEOPLASMS; MALE; MESOCRICETUS; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NEOPLASM PROTEINS; NEOPLASMS, HORMONE-DEPENDENT; PHODOPUS; POINT MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PROTO-ONCOGENE PROTEINS C-FOS; RECEPTORS, ESTROGEN; REGULATORY SEQUENCES, NUCLEIC ACID; SPECIES SPECIFICITY; TUMOR CELLS, CULTURED;

EID: 0032932415     PISSN: 08991987     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2744(199904)24:4<255::AID-MC3>3.0.CO;2-C     Document Type: Article

References (30)

1. Kirkman H. Estrogen-induced tumors of the kidney in the Syrian hamster. III. Growth characteristics in the Syrian hamster. J Natl Cancer Inst Monogr 1959;1:1-57.
2. Liehr JG, Sirbasku DA. Estrogen-dependent kidney tumors. In: Taub M, editor. Tissue culture of epithelial cells. New York: Plenum Press; 1985. p 205-234.
3. Liehr JG. Hormone-associated cancer: Mechanistic similarities between human breast cancer and estrogen-induced kidney carcinogenesis in hamsters. Environ Health Perspect 1997;105:565-569.
4. Liehr JG, Chiappetta C, Roy D, Stancel GM. Elevation of protooncogene messenger RNAs in estrogen-induced kidney tumors in the hamster. Carcinogenesis 1992;13:601-604.
5. Bhat HK, Hacker HJ, Thompson EB, Liehr JG. Differential regulation by estrogen of c-fos in hamster kidney and estrogen-induced kidney tumor cells: Receptor mediation vs. metabolic activation. Int J Oncol 1995;7:527-534.
6. Angel P, Karin M. The role of Jun, Fos, and the AP-1 complex in cell-proliferation and transformation. Biochim Biophys Acta 1991;1072:129-157.
7. Chen C, Clarkson R, Xie Y, Hume DA, Waters MJ. Growth hormone and colony-stimulating factor-1 share multiple response elements in the c-fos promoter. Endocrinology 1995;136:4504-4516.
8. Miller AD, Curran T, Verma I. c-fos protein can induce cellular transformation. Cell 1984;36:51-60.
9. Sirbasku DA, Kirkland WL. Control of cell growth. IV. Growth properties of a new cell line established from an estrogen-dependent kidney tumor of the Syrian hamster. Endocrinology 1976;89:1260-1272.
10. Weisz A, Bresciani B. Estrogen-induced expression of c-fos and c-myc protooncogenes in rat uterus. Mol Endocrinol 1998;2:816-824.
11. Loose-Mitchell DS, Chiappetta C, Stancel GM. Estrogen regulation of c-fos messenger ribonucleic acid. Mol Endocrinol 1998;2:946-951.
12. Bhat HK, Hacker HJ, Bannasch P, Thompson EA, Liehr JG. Localization of estrogen receptors in interstitial cells of hamster kidney and in estradiol-induced renal tumors as evidence of the mesenchymal origin of this neoplasm. Cancer Res 1993;53:5447-5451.
13. Nawaz Z, Stancel GM, McDonnell DP, Hyder SM. Creation of an active estrogen response element by single base change in the flanking sequence of a cellular oncogene: A possible mechanism for hormonal carcinogenesis? Mol Carcinog 1993;7:76-82.
14. Liehr JG, Roy D. Free radical generation by redox cycling of estrogens. Free Radiv Biol Med 1990;8:415-423.
15. Nutter LM, Wu YY, Ngo EO, Sierra EE, Gutierrez PL, Abul-Hajji YJ. An o-quinone form of estrogen produces free radicals in human breast cancer cells: Correlation with DNA damage. Chem Res Toxicol 1994;7:23-28.
16. Kodama M, Inoue F, Saito H, Ota T, Sato Y. Formation of free radicals from steroid hormones: Possible significance in environmental carcinogenesis. Anticancer Res 1997;17:439-444.
17. Woodgett JR, Avruch J, Kyriakis JM. Regulation of nuclear transcription factors by stress signals. Clin Exp Pharmacol Physiol 1995;22:281-283.
18. Janssen YMW, Heintz NH, Mossman BT. Induction of c-fos and c-jun proto-oncogene expression by asbestos is ameliorated by N-acetyl-L-cysteine in mesothelial cells. Cancer Res 1995;55: 2085-2089.
19. Schwab GE, Rancy JL, Johnson EF. Modulation of rabbit and human hepatic cytochrome P450-catalyzed steroid hydroxylations by α-naphthoflavone. Mol Pharmacol 1988;33:493-499.
20. Wiebel FJ. Activation and inactivation of carcinogens by microsomal monooxygenases. In: Slaga TJ, editor. Carcinogenesis: Modifiers of chemical carcinogenesis. New York: Raven Press; 1980. vol 5, p 57-84.
21. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-159.
22. Wang W, Howells RD. Sequence of the 5′-flanking region of the rat c-fos proto-oncogene. Gene 1994;143:261-264.
23. Sekiya T. Detection of mutant sequences by SSCP analysis. Mutat Res 1993;288:79-83.
24. Fan E, Levin DB, Glickman BW, Logan DM. Limitations in the use of SSCP analysis. Mutat Res 1993;288:85-92.
25. Davis LG, Kuehl WM, Battey JF. General methods. In: Basic methods in molecular biology, 2nd edition. Norwalk, CT: Appleton and Lange Publishing; 1994. p 15-44.
26. Pearson WR, Lipman DJ. Improved tools for biological sequence comparison. Proc Natl Acad Sci USA 1988;85:2444-2448.
27. Weisz A, Rosales R. Identification of an estrogen response element upstream of the c-fos gene that binds the estrogen receptor and the AP-1 transcription factor. Nucleic Acids Res 1990;18:5097-5106.
28. Hyder SM, Cram LF, Loose-Mitchell DS. Sequence of a 1.4 kb region in the 3′-flanking region of the murine c-fos protooncogene which contains an estrogen-response element. Gene 1991;105:281-282.
29. Hammond DK, Zhu BT, Yang MY, Ricci MJ, Liehr JG. Cytochrome P450 metabolism of estradiol in hamster liver and kidney. Toxicol Appl Pharmacol 1997;145:54-60.
30. Roy D, Bernhardt A, Strobel HW, Liehr JG. Catalysis of the oxidation of steroid and stilbene estrogens to estrogen quinone metabolites by the β-naphthoflavone-inducible cytochrome P450 IA family. Arch Biochem Biophys 1992;296:450-456.