IgG titer, subclass, and light-chain phenotype of pregnancy-induced HPA- 5b antibodies that cause or do not cause neonatal alloimmune thrombocytopenia

Transfusion

Volumn 39, Issue 4, 1999, Pages 379-382

  Kurz, Martin C ^a   Stöckelle, Eugen ^a   Eichelberger, Beate ^a   Panzer, Simon ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G; IMMUNOGLOBULIN LIGHT CHAIN; MONOCLONAL ANTIBODY; THROMBOCYTE ANTIGEN;

ALLOIMMUNIZATION; ANTIBODY TITER; ARTICLE; CLINICAL ARTICLE; HUMAN; NEWBORN; NEWBORN DISEASE; PHENOTYPE; PREGNANCY COMPLICATION; SEROLOGY; THROMBOCYTOPENIA;

EID: 0032930231     PISSN: 00411132     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1537-2995.1999.39499235669.x     Document Type: Article

References (14)

1. Newman PJ. Nomenclature of human platelet alloantigens: a problem with the HPA system? Blood 1994;83:1447-51.
2. Von dem Borne AE, de Hass M, Simsek S, et al. Platelet and neutrophil alloantigens in clinical medicine. Vox Sang 1996;70(Suppl 3):34-40.
3. Peyruchaud O, Bourre F, Morel-Kopp MC, et al. HPA-10w(b) [La(a)]: genetic determination of a new platelet-specific alloantigen on glycoprotein IIIa and its expression in COS-7 cells. Blood 1997;89:2422-8.
4. Panzer S, Kaplan C, on behalf of the ISBT Platelet and Granulocyte Workshop. Report on the 1997 International Society of Blood Transfusion Workshop for genotyping of platelet alloantigens. Transfus Med 1998;8:125-8.
5. Kaplan C, Morel-Kopp MC, Kroll H, et al. HPA-5b[Br(a)] neonatal alloimmune thrombocytopenia: clinical and immunological analysis of 39 cases. Br J Haematol 1991;78:425-9.
6. Ribera A, Parra R, Gallardo D, et al. Frequency of platelet antibodies against HPA-5b in Spanish pregnant women (abstract). Vox Sang 1994;67:12.
7. Panzer S, Auerbach L, Cechova E, et al. Maternal alloimmunization against fetal platelet antigens: a prospective study. Br J Haematol 1995;90:655-60.
8. Ulm B, Ulm MR, Deutinger J, et al. Spontaneous rise of fetal platelet counts despite increasing anti-HPA-5b antibodies. Vox Sang 1997;72:111-3.
9. Kumpel BM, Wiener E, Urbaniak SJ, Bradley BA. Human monoclonal anti-D antibodies. II. The relationship between IgG subclass, Gm allotype and Fc mediated function. Br J Haematol 1989;71:415-20.
10. Von dem Borne AE, van Leeuwen EF, von Riesz LE, et al. Neonatal alloimmune thrombocytopenia: detection and characterization of the responsible antibodies by the platelet immunofluorescence test. Blood 1981;57:649-56.
11. Proulx C, Filion M, Goldman M, et al. Analysis of immunoglobulin class, IgG subclass and titer of HPA-1a antibodies in alloimmunized mothers giving birth to babies with or without neonatal alloimmune thrombocytopenia. Br J Haematol 1994;87:813-7.
12. Kiefel V, Santoso S, Weisheit M, et al. Monoclonal anti-body-specific immobilization of platelet antigens (MAIPA): a new tool for the identification of platelet-reactive antibodies. Blood 1987;70:1722-6.
13. Benda H, Panzer S, Kiefel V, et al. Identification of the target platelet glycoprotein in autoimmune thrombocytopenia occurring after allogeneic bone marrow transplantation. Blut 1989;58:151-3.
14. Christie DJ, Sauro SC, Fairbanks KD, Kay NE. Detection of clonal platelet antibodies in immunologically-mediated thrombocytopenias: association with circulating clonal/ oligoclonal B cells. Br J Haematol 1993;85:277-84.