Investigation of the role of postnatal testosterone in the expression of sex differences in behavior in infant rhesus macaques (Macaca mulatta)

Hormones and Behavior

Volumn 35, Issue 2, 1999, Pages 186-194

  Brown, Gillian R ^a   Dixson, Alan F ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Infant behavior; Postnatal testosterone; Rhesus macaque; Sex differences

Indexed keywords

AVORELIN; GONADORELIN AGONIST; TESTOSTERONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHILD BEHAVIOR; CONTROLLED STUDY; FEMALE; GROWTH REGULATION; MALE; MOTHER CHILD RELATION; NEWBORN; NONHUMAN; PENIS; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; RHESUS MONKEY; SEX DIFFERENCE; SPECIES DIFFERENCE; TESTOSTERONE BLOOD LEVEL;

EID: 0032930178     PISSN: 0018506X     EISSN: None     Source Type: Journal    
DOI: 10.1006/hbeh.1999.1512     Document Type: Article

References (32)

1. Abbott D. H., Hearn J. P. The effects of neonatal exposure to testosterone on the development of behavior in female marmoset monkeys. Sex, Hormones and Behaviour, Ciba Found. Symp. 1979;. p. 299-313.
2. Boutignon F., Touchet H., David S., Wüthrich P., Deghenghi R., Ong H., Dubuc M., Cesana M., Maggi T. Protracted release of the LHRH agonist avorelin (MF 6001) from two depot formulations in dogs and men. Lett. Peptide Sci. 4:1997;423-427.
3. Brown, G. R. Nevison, C. M. Fraser, H. M. Dixson, A. F. Manipulation of postnatal testosterone affects phallic and clitoral development in infant rhesus monkeys, Int. J. Androl.
4. Corker C. S., Davidson D. W. A radioimmunoassay for testosterone in various biological fluids without chromatography. J. Steroid Biochem. 9:1978;373-374.
5. Dixson A. F. Plasma testosterone concentrations during postnatal development in the male common marmoset. Folia Primatol. 47:1986;166-170.
6. Dixson A. F., Brown G. R., Nevison C. M. Developmental significance of the postnatal testosterone "surge" in male primates. Ellis L., Ebertz L. Males, Females, and Behavior: Towards Biological Understanding. 1998;129-145 Praeger.
7. 4. J. Clin. Endocrin. Metab. 41:1975;977-980.
8. Forest M. G., Sizonenko P. C., Cathiard A. M., Bertrand J. Hypophyso-gonadal function in humans during the first year of life: I. Evidence for testicular activity in early infancy. J. Clin. Invest. 53:1974;819-828.
9. Frawley L. S., Neill J. D. Age related changes in serum levels of gonadotropins and testosterone in infantile male rhesus monkeys. Biol. Reprod. 20:1979;1147-1151.
10. Goldfoot D. A. Sociosexual behaviours of nonhuman primates during development and maturity: Social and hormonal relationships. Schrier A. M. Behavioral Primatology; Advances in Research and Theory. 1977;139-184 Lawrence Erlbaum, Hillsdale.
11. Goldfoot D. A., Wallen K. Development of gender role behaviors in heterosexual and isosexual groups of infant rhesus monkeys. Chivers D. J., Herbert J. Recent Advances in Primatology. 1978;155-159 Academic Press, London.
12. Goy R. W. Organizing effects of androgen on the behaviour of rhesus monkeys. Michael R. P. Endocrinology and Human Behaviour. 1968;12-31 Oxford Univ. Press, Oxford.
13. Goy R. W. Development of play and mounting behaviour in female rhesus virilised prenatally with esters of testosterone or dihydrotestosterone. Chivers D. J., Herbert J. Recent Advances in Primatology. 1978;449-462 Academic Press, London.
14. Hinde R. A., Rowell T. E., Spencer-Booth Y. Behaviour of socially living rhesus monkeys in their first six months. Proc. Zool. Soc. Lond. 143:1964;609-649.
15. Hinde R. A., Simpson M. J. A. Qualities of mother-infant relationships in monkeys. In CIBA Foundation. 33:1975;39-67.
16. Hinde R. A., White L. E. Dynamics of a relationship: Rhesus mother-infant ventro-ventral contact. J. Comp. Physiol. Psychol. 86:1974;8-23.
17. Hines M., Kaufman F. R. Androgen and the development of human sex-typical behaviour: Rough-and-tumble play and sex of preferred playmates in children with congenital adrenal hyperplasia (CAH). Child Dev. 65:1994;1042-1053.
18. Joslyn W. D. Androgen-induced social dominance in infant female rhesus monkeys. J. Child Pychol. Psychiat. 14:1973;137-145.
19. Mann D. R., Akinbami M. A., Gould K. G., Tanner J. M., Wallen K. Neonatal treatment of male monkeys with a gonadotrophin-releasing hormone agonist alters differentiation of central nervous system centers that regulate sexual and skeletal development. J. Clin. Endocrin. Metab. 76:1993;1319-1324.
20. Mann D. R., Castracane D., McLaughlin F., Gould K. G., Collins D. C. Developmental patterns of serum luteinizing hormone, gonadal and adrenal steroids in the sooty mangebey (Cercocebus atys. Biol. Reprod. 28:1983;279-284.
21. Mann D. R., Davis-DaSilva M., Wallen K., Coan P., Evans D. E., Collins D. C. Blockade of neonatal activation of the pituitary-testicular axis with continuous administration of a gonadotrophin-releasing hormone agonist in male rhesus monkeys. J. Clin. Endocrinol. Metab. 59:1984;207-211.
22. Mann D. R., Fraser H. M. The neonatal period: A critical interval in primate development. J. Endocrinol. 149:1996;191-197.
23. Mann D. R., Gould K. G., Collins D. C., Wallen K. Blockade of neonatal activation of the pituitary-testicular axis: Effect on peripubertal luteinizing hormone and testosterone secretion and on testicular development in male monkeys. J. Clin. Endocrin. Metab. 68:1989;600-607.
24. Martin P., Bateson P. Measuring Behaviour: An Introductory Guide. 1986;Cambridge Univ. Press, Cambridge.
25. Nevison C. M., Brown G. R., Dixson A. F. Effects of altering testosterone in early infancy on social behaviour in captive yearling rhesus monkeys. Physiol. Behav. 62:1997;1397-1403.
26. Robinson J. A., Bridson W. E. Neonatal hormone patterns in the macaque. 1. Steroids. Biol. Reprod. 19:1978;773-778.
27. Siegel S., Castellan N. J. Nonparametric Stastistics for the Behavioural Sciences. 1988;McGraw-Hill.
28. Simpson M. J. A., Gore M. A., Janus M., Rayment F. D. G. Prior experience of risk and individual differences in enterprise shown by rhesus monkey infants in the second half year of life. Primates. 30:1989;493-509.
29. Steiner R. A., Bremner W. J. Endocrine correlates of sexual development in the male monkey,Macaca fascicularis. Endocrinology. 109:1981;914-919.
30. Wallen K. Nature needs nurture: the interaction of hormonal and social influences on the development of behavioral sex differences in rhesus monkeys. Horm. Behav. 30:1996;364-378.
31. Wallen K., Maestripieri D., Mann D. R. Effects of neonatal testicular suppression with a GnRH antagonist on social behavior in group-living juvenile rhesus monkeys. Horm. Behav. 29:1995;322-337.
32. Zar J. H. Biostastistical Analysis. 1974;Prentice-Hall.