Thrombolytic therapy for acute ischemic stroke: Why the majority of patients remain ineligible for treatment

Annals of Emergency Medicine

Volumn 33, Issue 1, 1999, Pages 9-14

  O'Connor, R E ^a   McGraw, P ^a   Edelsohn, L ^a  

^a CHRISTIANA CARE HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BLEEDING; BRAIN SCINTISCANNING; FIBRINOLYTIC THERAPY; HEART ARREST; HEART MUSCLE ISCHEMIA; HUMAN; MAJOR CLINICAL STUDY; MULTICENTER STUDY; PATIENT SELECTION; PRIORITY JOURNAL; RESUSCITATION; STROKE; SYMPTOMATOLOGY; TREATMENT CONTRAINDICATION; TREATMENT PLANNING;

EID: 0032930098     PISSN: 01960644     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-0644(99)70411-7     Document Type: Article

References (28)

1. Division of Chronic Disease Control and Community Intervention Cardiovascular Disease Surveillance: Stroke , 1980-1989 1994 Centers for Disease Control and Prevention Atlanta, GA
2. American Heart Association Heart and Stroke Facts, 1997 Statistical Supplement 1997 American Heart Association Dallas, TX
3. C Fieschi C Argentino GL Lenzi Clinical and instrumental evaluation of patients with ischemic stroke within the first six hours J Neurosci 91 1989 311 322
4. GJ del Zoppo K Poeck MS Pessin Recombinant tissue plasminogen activator in acute thrombotic and embolic stroke Ann Neurol 32 1992 78 86
5. The National Institute of Neurologic Disorders and Stroke rt-PA Stroke Study Group Tissue plasminogen activator for acute ischemic stroke N Engl J Med 333 1995 1581 1587
6. Multicentre Acute Stroke Trial-Italy MAST-I Group Randomized controlled trial of strepto-kinase, aspirin, and combination of both in treatment of acute ischemic stroke Lancet 346 1995 1509 1514
7. The Multicenter Acute Stroke Trial-Europe MAST-E Study Group Thrombolytic therapy with streptokinase in acute ischemic stroke N Engl J Med 335 1996 145 150
8. GA Donnan SM Davis BR Chambers Streptokinase for acute ischemic stroke with relationship to time of administration JAMA 276 1996 961 966
9. W Hacke M Kaste C Fieschi Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke: The European cooperative acute stroke study (ECASS) JAMA 274 1995 1017 1025
10. HP Adams TG Brott AJ Furlan Guidelines for thrombolytic therapy for acute stroke: A supplement to the management of patients with acute ischemic stroke. A statement for healthcare professionals from a special writing group of the stroke council, American Heart Association Stroke 27 1996 1711 1718
11. The National Institute of Neurologic Disorders and Stroke rt-PA Stroke Study Group A systems approach to immediate evaluation and management of hyperacute stroke Stroke 28 1997 1530 1540
12. WD Rosamond RA Gorton AR Hinn Rapid response to stroke symptoms: The delay in accessing stroke healthcare (DASH) study Acad Emerg Med 5 1998 45 51
13. P Lyden T Brott Tilley Improved reliability of the NIH Stroke Scale using video training Stroke 25 1994 2220 2226
14. MA Albanese WR Clarke HP Adams Jr Ensuring reliability of outcome measures in multicenter clinical trials of treatments for acute ischemic stroke: The program developed for the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) Stroke 25 1994 1746 1751
15. AJ Furlan STD Kanoti When is thrombolysis justified in patient with acute ischemic stroke? A bioethical perspective Stroke 28 1997 214 218
16. MA Safer QJ Tharps TC Jackson Determinant of three stages of delay in seeking care at a medical clinic Med Care 17 1979 11 29
17. RF Gillum M Feinleib JR Margolis Delay in the prehospital phase of acute myocardial infarction. Lack of influence on incidence of sudden death Arch Intern Med 136 1976 649 654
18. National Heart Attack Alert Program Patient/Bystander Recognition and Action: Rapid Identification and Treatment of Acute Myocardial Infarction 1993 National Institutes of Health, National Heart, Lung, and Blood Institute (publication no. 93-3303)
19. AA Alonzo An illness behavior paradigm: A conceptual exploration of a situational-adaptation perspective Soc Sci Med 19 1984 499 510
20. AA Alonzo Acute illness behavior: A conceptual exploration and specification Soc Sci Med 14A 1980 515 526
21. Subcommittee on Advanced Cardiac Life Support Textbook of Advanced Cardiac Life Support 1997 American Heart Association Dallas, TX
22. SE Kasner JC Grotta Emergency identification and treatment of acute ischemic stroke Ann Emerg Med 30 1997 642 653
23. SJ Ellis M Small Denial of illness in stroke Stroke 24 1993 757 759
24. E Feldman N Gordon JM Brooks Factors associated with early presentation of acute stroke Stroke 24 1993 1805 1810
25. MJ Alberts C Bertels DV Dawson An analysis of the time to presentation after stroke JAMA 263 1990 65 68
26. WG Barsan TG Brott JP Broderick Urgent therapy for acute stroke: Effects of a stroke trial on untreated patients Stroke 25 1994 2132 2137
27. WG Barsan TG Brott JP Broderick Time of hospital presentation in patients with acute stroke Arch Intern Med 153 1993 2558 2561
28. P Bratina L Greenberg W Pasteur Current emergency department management of stroke in Houston, Texas Stroke 26 1995 409 414