Ten-year experience of unrelated bone marrow donor transplants in children with malignant and non-malignant conditions

Pediatric Transplantation

Volumn 3, Issue 1, 1999, Pages 49-59

  Trigg, Michael E ^a,b   Rumelhart, Stephen L ^a   Miller, Jennifer ^a   Goldman, Frederick D ^a   Holida, Myrl D ^a   Lee, Nita F ^a  

^a UNIVERSITY OF IOWA   (United States)

^b NEMOURS ALFRED I DUPONT HOSPITAL FOR CHILDREN   (United States)

Author keywords

Leukemia; Transplantation; Unrelated donors

Indexed keywords

ADOLESCENT; ARTICLE; BONE MARROW DISEASE; BONE MARROW TRANSPLANTATION; CAUSE OF DEATH; CHILD; FEMALE; GRAFT REJECTION; GRAFT SURVIVAL; GRAFT VERSUS HOST REACTION; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; MORBIDITY; ORGAN DONOR; TREATMENT INDICATION;

ADOLESCENT; BONE MARROW TRANSPLANTATION; CHILD; CHILD, PRESCHOOL; GRAFT VS HOST DISEASE; HISTOCOMPATIBILITY TESTING; HOSPITALS, UNIVERSITY; HUMANS; INFANT; IOWA; LIFE TABLES; MORBIDITY; REGISTRIES; SURVIVAL ANALYSIS; TRANSPLANTATION CONDITIONING; TRANSPLANTATION, HOMOLOGOUS; TREATMENT OUTCOME;

EID: 0032929505     PISSN: 13973142     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3046.1999.00008.x     Document Type: Article

References (37)

1. KERNAN NA, BARTSCH G, ASH RC, et al. Analysis of 462 transplantations from unrelated donors facilitated by the National Marrow Donor Program. N Engl J Med 1993: 328: 593.
2. PETERS CP, BALTHAZOR M, SHAPIRO EG, et al. Outcome of unrelated donor bone marrow transplantation in forty children with Hurler syndrome. Blood 1996: 87: 4894.
3. BEATTY PG, HANSEN JA, LONGTON GM, et al. Marrow transplantation from HLA-matched unrelated donors for treatment of hematologic malignancies. Transplantation 1991: 51: 443.
4. BEATTY PG. Marrow transplantation using volunteer unrelated donors in a comparison of mismatched family donor transplants: a Seattle perspective. Bone Marrow Transplant 1994: 14: S39.
5. WAGNER JE, KERNAN NA, STEINBACH M, BROXMEYER H, GLUCKMAN E. Allogeneic sibling umbilical cord blood transplantation in children with malignant and non-malignant disease. Lancet 1995: 346: 214.
6. GROVAS A, FEIG SA, O'ROURKE S, et al. Unrelated donor bone marrow transplants in children. Cell Transplant 1994: 3: 413.
7. DAVIES SM, RAMSAY NKC, HAAKE RJ, et al. Comparison of engraftment in recipients of matched siblings or unrelated donor marrow allografts. Bone Marrow Transplant 1994: 13: 51.
8. BALDUZZI A, GOOLEY T, ANASETTI C, et al. Unrelated donor marrow transplantation in children. Blood 1995: 86: 3247.
9. CASPER J, CAMITTA B, TRUITT R, et al. Unrelated bone marrow transplants for children with leukemia or myelodysplasia. Blood 1995: 85: 2354.
10. TRIGG ME. Status of BMT in children using either unrelated donors or partially matched family members: engraftment issues, GvHD incidence and prevention and risk for infection. In: Proceedings of the International Symposium on Hemopoietic Stem Cell Research and its Clinical Application. Korea: Kwangju, 1994, pp. 57-77.
11. TRIGG ME, GINGRICH R, GOEKEN N, et al. Low ejection rate when using unrelated or haploidentical donors for children with leukemia undergoing marrow transplantation. Bone Marrow Transplant 1989: 4: 431.
12. TRIGG ME, BILLING R, SONDEL PM, et al. Mismatched bone marrow transplantation in children with hematologic malignancy using T-lymphocyte depleted bone marrow. J Biol Response Mod 1985: 4: 602.
13. TRIGG ME, PETERSON A, ERICKSON C, et al. Depletion of T-cells from bone marrow for allogeneic transplantation: method for treatment of bone marrow in bulk. Exp Hematol 1986: 14: 21.
14. TRIGG ME. What is the merit of an alternative bone marrow transplant? Bone Marrow Transplant 1996: 18 (Suppl. 3): S28.
15. LEE C-K, GINGRICH RD, HARMAN GS, et al. Anti-CD 3 (OKT3) T cell depletion and add-back (TCD-AB): comparative analysis with anti-CD2 (CT2) TCD-AB in allogeneic bone marrow transplantation (BMT). Blood 1995: 86: 507a.
16. KOOK H, TRIGG ME. Reconstruction of the immune system after unrelated or partially matched T-cell depleted bone marrow transplantation in children. In: Proceedings of the International Symposium on Hemopoietic Stem Cell Research and its Clinical Application. Korea: Kwangju, 1994. pp. 47-56.
17. KOOK H, GOLDMAN F, PADLEY D, et al. Reconstruction of the immune system after unrelated or partially matched T-cell depleted bone marrow transplantation in children: immunophenotypic analysis and factors affecting the speed of recovery. Blood 1996: 88: 1089.
18. KOOK H, GOLDMAN F, GILLER R, et al. Reconstruction of the immune system after unrelated or partially matched T-cell depleted bone marrow transplantation in children: functional analyses of lymphocytes and correlation with immunophenotypic recovery following transplant. Clin Diagn Lab Immunol 1997: 4: 96-103.
19. TRIGG ME, BILLING R, SONDEL PM, et al. Depletion of T-cells from human bone marrow with monoclonal antibody CT-2 and complement. J Biol Response Mod 1984: 3: 406.
20. SONDEL PM, HANK JA, MOLENDA J, et al. Relapse of host leukemic lymphoblasts following engraftment by an HLA-mismatched marrow transplant: mechanisms of escape from 'graft versus leukemia' effect. Exp Hematol 1985: 13: 782.
21. BOZDECH MJ, SONDEL PM, TRIGG ME, et al. Transplantation of HLA-haploidentical T-cell depleted marrow for leukemia: addition of cytosine arabinoside to the pre-transplant conditioning prevents rejection. Exp Hematol 1985: 13: 1201.
22. TRIGG ME. Bone marrow transplantation using alternative donors: mismatched related donors or closely matched unrelated donors. Am J Pediatr Hematol Oncol 1993: 15: 141.
23. JENNY MEM. Umbilical cord blood transplantation: is there a future? Lancet 1995: 346: 921.
24. DROBYSKI WR, ASH RC, CASPER JT, et al. Effect of T-cell depletion as graft-versus-host disease prophylaxis on engraftment, relapse, and disease-free survival in unrelated marrow transplantation for chronic myelogenous leukemia. Blood 1994: 83: 1980.
25. BEARMAN SI, MORI M, BEATTY PG, et al. Comparison of morbidity and mortality after marrow transplantation from HLA-genotypically identical siblings and HLA-phenotypically identical unrelated donors. Bone Marrow Transplant 1994: 13: 31.
26. ANASETTI C, HOWE C, PETERSDORF EW, MARTIN PG, HANSEN JA. Marrow transplants from HLA matched unrelated donors: an NMDP update and the Seattle experience. Bone Marrow Transplant 1994: 13: 693.
27. BEARMAN SI, MORI M, BEATTY PG, et al. Comparison of morbidity and mortality after marrow transplantation from HLA-genotypically identical siblings and HLA-phenotypically identical unrelated donors. Bone Marrow Transplant 1994: 13: 31.
28. HESSNER MJ, ENDEAN DJ, CASPER JT, et al. Use of unrelated marrow grafts compensates for reduced graft-versus-leukemia reactivity after T-cell-depleted allogeneic marrow transplantation for chronic myelogenous leukemia. Blood 1995: 86: 3987.
29. KOLB HJ, SCHATTENBERG A, GOLDMAN JM, et al. Graft-versus-leukemia effect of donor lymphocyte transfusions in marrow grafted patients. Blood 1995: 86: 2041.
30. SKINNER J, FINLAY JF, SONDEL PM, TRIGG ME. Infectious complications in pediatric patients undergoing transplantation with T-lymphocyte depleted bone marrow. Pediatr Infect Dis 1986: 5: 319.
31. TRIGG ME, PADLEY D. Depletion of T-cells from bone marrow for allogeneic transplantation: quantitation of lymphocyte subclasses remaining in marrow following depletion. Bone Marrow Transplant 1989: 4: 454.
32. HOWE J, BRADLEY BA, GORE S, DOWNIE T, HOWARD M, GLUCKMAN E. Prospective evaluation of unrelated donor bone marrow transplantation. Bone Marrow Transplant 1993: 12: 371.
33. BEATTY PG, ANASETTI C, HANSEN JA, et al. Marrow transplantation from unrelated donors for treatment of hematologic malignancies: effect of mismatching for one HLA locus. Blood 1993: 81: 249.
34. MCGLAVE P, BARTSCH G, ANASETTI C, et al. Unrelated donor marrow transplantation therapy for chronic myelogenous leukemia: initial experience of the National Marrow Donor Program. Blood 1993: 81: 543.
35. SAHFEBI F, BOLWELL B, CRILLEY P, et al. Unrelated allogeneic bone marrow transplantation using high dose busulfan and cyclophosphamide (Bu-Cy) conditioning regimen. Blood 1993: 82: 81a.
36. AVERSA F, TABILIO A, TERENZI A, et al. Successful engraftment of T-cell-depleted haploidentical 'three-loci' incompatible transplants in leukemia patients by addition of recombinant human granulocyte colony-stimulating factor mobilized peripheral blood progenitor cells to bone marrow inoculum. Blood 1994: 84: 3948.
37. MORI M, GRAVES M, MILFORD CL, BEATTY PG. Computer program to predict likelihood of finding an HLA-matched donor: methodology, validation and application. Biol Blood and Marrow Transplant 1996: 2: 134.