Effects of long-term angiotensin II AT1 receptor blockade on survival, hemodynamics and cardiac remodeling in chronic heart failure in rats

Cardiovascular Research

Volumn 41, Issue 1, 1999, Pages 100-108

  Richer, Christine ^a   Fornes, Paul ^a   Cazaubon, Catherine ^b   Domergue, Valérie ^a   Nisato, Dino ^b   Giudicelli, Jean François ^a  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b SANOFI   (France)

Author keywords

Angiotensin II AT1 receptor blockade; Cardiac remodeling; Experimental heart failure; Hemodynamics; Rat; Survival

Indexed keywords

ANGIOTENSIN RECEPTOR; ANGIOTENSIN RECEPTOR ANTAGONIST; IRBESARTAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; DOSE RESPONSE; HEART FAILURE; HEART INDEX; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE FIBROSIS; HEART VENTRICLE HYPERTROPHY; HEMODYNAMICS; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; URINARY EXCRETION;

ANALYSIS OF VARIANCE; ANGIOTENSIN II; ANIMALS; ANTIHYPERTENSIVE AGENTS; BIPHENYL COMPOUNDS; DOSE-RESPONSE RELATIONSHIP, DRUG; HEART FAILURE, CONGESTIVE; HEART RATE; MALE; RATS; RATS, WISTAR; RECEPTORS, ANGIOTENSIN; SURVIVAL RATE; TETRAZOLES; VASCULAR RESISTANCE; VENTRICULAR PRESSURE; VENTRICULAR REMODELING;

EID: 0032928804     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(98)00227-2     Document Type: Article

References (36)

1. The CONSENSUS Trial Study Group Effects of enalapril on mortality in severe congestive heart failure: results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). New Engl J Med 1987;316:1429-1435.
2. The SOLVD Investigators Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. New Engl J Med 1991;325:293-302.
3. SAVE Effect of capropril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction: results of the survival and ventricular enlargement trial. New Engl J Med 1992;327:669-677.
4. The Acute Infarction Ramipril Efficacy (AIRE) Study Investigators Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure. Lancet 1993;342:821-828.
5. ISIS-4 (fourth International Study of Infarct Survival) Collaborative Group ISIS-4: a randomised factorial trial assessing early oral captopril, oral mononitrate and intravenous magnesium sulphate in over 58 050 patients with suspected acute myocardial infarction. Lancet 1995;345:669-685.
6. Pfeffer MA, Pfeffer JM, Steinberg C, Finn P. Survival after an experimental myocardial infarction: beneficial effects of long-term therapy with captopril. Circulation 1985;72:406-412.
7. Sweet CS, Emmert SE, Stabilito II, Ribeiro LGT. Increased survival in rats with congestive heart failure treated with enalapril. J Cardiovasc Pharmacol 1987;10:636-642.
8. Richer C, Mulder P, Fornes P, et al. Long-term treatment with trandolapril opposes cardiac remodeling and prolongs survival after myocardial infarction rats. J Cardiovasc Pharmacol 1992;20:147-156.
9. Fornes P, Richer C, Pussard E, et al. Beneficial effects of trandolapril on experimentally induced congestive heart failure in rats. Am J Cardiol 1992;70:43D-51D.
10. Mulder P, Devaux B, Richard V, et al. Early versus delayed angiotensin-converting enzyme inhibition in experimental chronic heart failure. Effects on survival, hemodynamics, and cardiovascular remodeling. Circulation 1997;95:1314-1319.
11. Pfeffer JM, Pfeffer MA, Braunwald E. Influence of chronic captopril therapy on the infarcted left ventricle of the rat. Circ Res 1985;57:84-95.
12. Wollert KC, Studer R, Just H, et al. Influence of lisinopril on long-term mortality in rats with chronic myocardial infarction: role of blood pressure reduction and tissue ACE inhibition. Circulation 1994;90:2457-2467.
13. Michel JB, Lattion AL, Salzmann JL, et al. Hormonal and cardiac effects of converting enzyme inhibition in rat myocardial infarction. Circ Res 1988;62:641-650.
14. Mulder P, Devaux B, Elfertak L, et al. Vascular and myocardial protective effects of converting enzyme inhibition in experimental heart failure. Am J Cardiol 1995;76:28E-33E.
15. Gaudron P, Hu K, Zdrojewski T, et al. Effects of ACE-inhibitor on mortality in rats with acute experimental myocardial infarction are bradykinin breakdown dependent (Abstract). Circulation 1996;94(Suppl.I):3553.
16. Timmermans PB, Wong PC, Chiu AT, et al. Angiotensin II receptors and angiotensin II receptor antagonists. Pharmacol Rev 1993;45:205-251.
17. Liu YH, Yang XP, Sharov VG, et al. Effects of angiotensin-convert-ing enzyme inhibitors and angiotensin II type 1 receptor antagonists in rats with heart failure. J Clin Invest 1997;99:1926-1935.
18. Urata H, Healy B, Stewart RW, Bumpus FM, Husain A. Angiotensin Il-forming pathways in normal and failing human hearts. Circ Res 1990;66:883-890.
19. Gottlieb SS, Dickstein K, Fleck E, et al. Hemodynamic and neurohormonal effects of the angiotensin II antagonist losartan in patients with congestive heart failure. Circulation 1993;88:1602-1609.
20. Pitt B, Segal R, Martinez FA. Randomised trial of losartan versus captopril in patients over 65 with heart failure (evaluation of losartan in the elderly study, ELITE). Lancet 1997;349:747-752.
21. Yusuf S, Maggioni AP, Held P, Rouleau JL. Effects of candesartan, enalapril or their combination on exercise capacity, ventricular function, clinical deterioration and quality of life in heart failure: randomized evaluation of strategies for left ventricular dysfunction (Resolvd). Circulation 1997:96:1452, Abstract 2527.
22. Milavetz JJ, Raya TE, Johnson CS, Morkin E, Goldman S. Survival after myocardial infarction in rats: captopril versus losartan. J Am Coll Cardiol 1996;27:714-719.
23. 1 subtype angiotensin II receptor antagonist. J Pharmacol Exp Ther 1993;265:826-834.
24. Vacher E, Fornes P, Richer C, et al. Early and late haemodynamic and morphological effects of angiotensin II subtype 1 receptor blockade during genetic hypertension development. J Hypertens 1995;13:675-682.
25. Pfeffer MA, Pfeffer JM, Fishbein MC, et al. Myocardial infarct size and ventricular function in rats. Circ Res 1979;44:503-512.
26. McDevitt DG, Nies AS. Simultaneous measurement of cardiac output and its distribution with microspheres in the rat. Cardiovasc Res 1976;10:494-498.
27. Mantel N. Chi-square tests with one degree of freedom: extension of the Mantel-Haenszel procedure. J Am Stat Assoc 1963;58:690-700.
28. Michel JB, Mercadier JJ, Galen FX, et al. Urinary cyclic guanosine monophosphate as an indicator of experimental congestive heart failure in rats. Cardiovasc Res 1990;24:946-952.
29. Mulder P, Richard V, Hogie M, et al. Divergent long term effects of calcium antagonists in a rat model of chronic heart failure. Circulation 1997;96:I-524.
30. Schieffer B, Wirger A, Meybrunn M, et al. Comparative effects of chronic angiotensin-converting enzyme inhibition and angiotensin II type 1 receptor blockade on cardiac remodeling after myocardial infarction in the rat. Circulation 1994;89:2273-2282.
31. Anversa P, Beghi C, Kikkawa Y, Olivetti G. Myocardial infarction in rats: infarct size, myocyte hypertrophy and capillary growth. Circ Res 1986;58:26-37.
32. Tomanek RJ. Response of the coronary vasculature to myocardial hypertrophy. J Am Coll Cardiol 1990;15:528-533.
33. Zhu YC, Zhu YZ, Gohlke P, Stauss HM, Unger T. Effects of angiotensin-converting enzyme inhibition and angiotensin II ATI receptor antagonism on cardiac parameters in left ventricular hypertrophy. Am J Cardiol 1997;80(3A):110A-117A.
34. Booz GW, Baker KM. Role of type 1 and type 2 angiotensin receptors in angiotensin II-induced cardiomyocyte hypertrophy. Hypertension 1996;28:635-640.
35. Smits JFM, Van Krimpen C, Schoemaker RG, et al. Angiotensin II receptor blockade after myocardial infarction in rats: effects on hemodynamics, myocardial DNA synthesis, and interstitial collagen content. J Cardiovasc Pharmacol 1992;20:772-778.
36. Taylor K, Patten R, Smith JJ, et al. Divergent effects of angiotensin converting enzyme inhibition and angiotensin receptor antagonism on cell proliferation, collagen deposition and ventricular remodeling following myocardial infarction in rats. Circulation 1995;92:I25, Abstract 0113.