A photodynamic pathway to apoptosis and necrosis induced by dimethyl tetrahydroxyhelianthrone and hypericin in leukaemic cells: Possible relevance to photodynamic therapy

British Journal of Cancer

Volumn 79, Issue 3-4, 1999, Pages 423-432

  Lavie, G ^a,b   Kaplinsky, C ^a   Toren, A ^a   Aizman, I ^a   Meruelo, D ^b   Mazur, Y ^c   Mandel, M ^a  

^a SHEBA MEDICAL CENTER   (Israel)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^c WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Apoptosis; Bax; Bcl X; Dimethyl tetrahydroxyhelianthrone; Hypericin; Lamin; Photodynamic therapy

Indexed keywords

DIMETHYL TETRAHYDROXYHELIANTHRONE; DNA FRAGMENT; HYPERICIN; LAMIN; LAMIN B; PHOTOSENSITIZING AGENT; PROTEIN BCL X; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL DEATH; CELL NUCLEUS MEMBRANE; CELL STRAIN HL 60; CELL STRAIN K 562; CHROMATIN CONDENSATION; CONTROLLED STUDY; DNA DEGRADATION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PHOTODYNAMIC THERAPY; PHOTOSENSITIZATION; POLYMERIZATION; PRIORITY JOURNAL;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL NUCLEUS; DNA, NEOPLASM; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, BCL-1; GENES, BCL-2; HL-60 CELLS; HUMANS; NECROSIS; PERYLENE; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RADIATION-SENSITIZING AGENTS;

EID: 0032928325     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6690066     Document Type: Article

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