Chronic fatigue syndrome is an acquired neurological channelopathy

Human Psychopharmacology

Volumn 14, Issue 1, 1999, Pages 7-17

  Chaudhuri, Abhijit ^a   Behan, Peter O ^a  

^a SOUTHERN GENERAL HOSPITAL   (United Kingdom)

Author keywords

Chronic fatigue syndrome; Depression; Epilepsy; Ion channels; Migraine; Neuronal instability

Indexed keywords

ANTIDEPRESSANT AGENT; ION CHANNEL;

ARTICLE; CELL MEMBRANE; CHRONIC FATIGUE SYNDROME; DEPRESSION; DISEASE SEVERITY; EPILEPSY; FATIGUE; HUMAN; INJURY; MENTAL PERFORMANCE; MIGRAINE; MULTIPLE SCLEROSIS; NEUROENDOCRINE SYSTEM; NEUROMUSCULAR DISEASE; PARKINSON DISEASE; PHYSICAL ACTIVITY; PRIORITY JOURNAL; SHY DRAGER SYNDROME; STEROID METABOLISM; STRESS; SYMPTOM;

EID: 0032928295     PISSN: 08856222     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1077(199901)14:1<7::AID-HUP64>3.0.CO;2-O     Document Type: Article

References (70)

1. Ackerman, M. J. and Clapham, D. E. (1997). Ion channels - basic science and clinical disease. New England Journal of Medicine, 336, 1575-1586.
2. Artellano, R. O. and Miledi, R. (1993). Novel Cl - currents elicited by follicle stimulating hormone and acetylcholine in follicle enclosed xenopus oocytes. Journal of General Physiology, 102, 833-857.
3. Bakheit, A. M. O., Behan, P. O., Watson, W. S. and Morton, J. J. (1993). Abnormal arginine-vasopressin secretion and water metabolism in patients with post-viral fatigue syndrome. Acta Neurologica Scandinavica, 87, 234-238.
4. Bakheit, A. M. O., Behan, P. O., Dinan, T. G. et al. (1992). Possible upregulation of hypothalamic 5-hydroxytryptamine receptors in patients with post-viral fatigue syndrome. British Medical Journal, 304, 1010-1012.
5. Barnes, P. R. J., Taylor, D. J., Kemp, G. J. and Radda, G. K. (1993). Skeletal muscle bioenergetics in the chronic fatigue syndrome. Journal of Neurology Neurosurgery & Psychiatry, 56, 679-683.
6. Barron, J. L., Noakes, T. D., Levy, W. and Smith, C. (1985). Hypothalamic dysfunction in overtrained athletes. Journal of Clinical Endocrinology & Metabolism, 60, 803-806.
7. + channel toxin. Journal of Biological Chemistry, 259, 8353-8357.
8. Blauer, K. L., Poth, M., Rogers, W. M. and Bernton, E. W. (1991). Dehydroepiandrosterone antagonizes the suppressive effects of dexamethasone on lymphocyte proliferation. Endocrinology, 129, 3174-3179.
9. Bloomquist, J. R. (1996). Ion channels as targets for insecticides. Annual Review of Entomology, 41, 163-190.
10. Bou-Holaigh, I., Rowe, P. C., Kan, J. S. and Calkins, H. (1995). The relationship between neurally mediated hypotension and chronic fatigue syndrome. Journal of the American Medical Association, 274, 961-967.
11. Boudoulas, H., Tyson, C. C., Leighton, R. F. and Wilt, S. M. (1974). Myocardial lactate production in patients with angina-like chest pain and angiographically normal coronary arteries and left ventricle. American Journal of Cardiology, 34, 501-505.
12. Bradford, H. F. (1986). Chemical Neurobiology: an Introduction to Neurochemistry, W. H. Freeman & Co., New York.
13. Buchwald, D. and Komaroff, A. L. (1991). Review of laboratory findings for patients with chronic fatigue syndrome. Review of Infectious Diseases, 13 (Suppl 1), S12-S18.
14. Carrasco, L., Perez, L., Irurzun, A. et al. (1993). Modification of membrane permeability by animal viruses. In Regulation of Gene Expression in Animal Viruses, Carrasco, L. et al. (Eds), Plenum Press, New York, pp. 283-303.
15. Chaudhuri, A. and Behan, P. O. (1998a). Overlap syndromes of chronic fatigue. CNS, 1(2), 16-20.
16. Chaudhuri, A. and Behan, P. O. (1998b). Chronic fatigue syndrome after chronic low dose organophosphate exposure. American Journal of Medicine (in press).
17. Chaudhuri, A., Behan, W. M. H. and Behan, P. O. (1998). Chronic fatigue syndrome. Proceedings of the Royal College of Physicians, Edinburgh, 28, 150-163.
18. Chaudhuri, A., Majeed, T., Dinan, T. and Behan, P. O. (1997a). Chronic fatigue syndrome: a disorder of central cholinergic transmission. Journal of Chronic Fatigue Syndrome, 3(1), 3-16.
19. Chaudhuri, A., Watson, W. and Behan, P. O. (1997b). Factors influencing energy expenditure and therapeutic strategies in chronic fatigue syndrome. Journal of Neurological Science, 150, S225.
20. Chaudhuri, A., Watson, W. S., and Behan, P. O. (1997). Arguments for a role of abnormal ionophore function in chronic fatigue syndrome. In Chronic Fatigue Syndrome, Yehuda, S. and Mostofsky, D. I. (Eds), Plenum Press, New York, pp. 119-130.
21. Chrousos, G. P. (1995). The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation. New England Journal of Medicine, 332, 1351-1362.
22. Cleare, A. J., Bearn, J., Allain, T. et al. (1995). Contrasting neuroendocrine responses in depression and chronic fatigue syndrome. Journal of Affective Disorders, 343, 283-289.
23. Demitrack, M. A., Dale, J. K., Strauss, S. E. et al. (1991). Evidence for impaired activation of HPA axis in patients with chronic fatigue syndrome. Journal of Clinical Endocrinology and Metabolism, 73, 1124-1134.
24. Engstorm, I., Waldenstrom, A., Nilsson-Ehle, P. and Ronquist, D. (1993). Dissipation of the calcium gradient in human erythrocytes results in increased heat production. Clinica Chimica Acta, 219, 113-122.
25. Friedman, J. and Friedman, H. (1993). Fatigue in Parkinson's disease, Neurology, 43, 2016-2018.
26. Friedman, A., Kaufer, D., Shemer, J. et al. (1996). Pyridostigmine brain penetration under stress enhances neuronal excitability and induces early immediate transcriptional response. Nature Medicine, 2, 1382-1384.
27. Fukuda, K., Strauss, S. E., Hickie, I., Sharpe, M. C., Dobbins, J. G. and Komaroff, A. (1994). The chronic-fatigue syndrome: a comprehensive approach to its definition and study. Annals of Internal Medicine, 121, 953-959.
28. Garry, R. F., Kort, J. J., Koch-Nolte, F. and Koch, G. (1991). Similarities of viral proteins to toxins that interact with monovalent cation channels. AIDS, 5, 1381-1384.
29. Gower, W. R. (1907). The Borderland of Epilepsy: Faints, Vagal Attacks, Vertigo, Migraine, Sleep Symptoms and their Treatment, Churchill, London.
30. Greenberg, D. A. (1997). Calcium channels in neurological disease. Annals of Neurology, 42, 275-282.
31. +-ATPase in McArdle disease. Neurology, 50, 37-40.
32. Hamalainen, M. L., Autti, T., Salonen, O. and Santavuori, P. (1996). Brain MRI in children with migraine: a controlled morphometric study. Cephalalgia, 16, 541-544.
33. Harbuz, M. S. and Lightman, S. L. (1992). Stress and hypothalamo-pituitary-adrenal axis: acute and chronic immunological activation. Journal of Endocrinology, 134, 327-329.
34. Harbuz, M. S., Rees, R. G., Eckland, D. et al. (1992). Paradoxical responses of hypothalamic CRF mRNA and CRF-41 peptide and adenohypophyseal POMC mRNA during chronic inflammatory stress. Endocrinology, 130, 1394-1400.
35. Hilgers, A., Frank, J. and Bolte, P. (1998). Prolongation of central motor conduction time in chronic fatigue syndrome. Journal of Chronic Fatigue Syndrome, 4(2), 23-32.
36. Ikeda, K., Wu, D. and Takasaka, T. (1995). Inhibition of acetylcholine evoked Cl - currents by 14 membered macrolide antibiotic in isolated acinar cells of guineapig nasal gland. American Journal of Respiratory Cell and Molecular Biology, 13, 449-454.
37. Kaufer, D., Friedman, A., Seidman, S. and Soreq, H. (1998). Acute stress facilitates long lasting changes in cholinergic gene expression. Nature, 393, 373-377.
38. Lane, R. J. M., Burgess, A. P., Flint, J., Riccio, M. and Archard, L. M. (1995). Exercise responses and psychiatric disorder in chronic fatigue syndrome. British Medical Journal, 311, 544-545.
39. Lerner, A. M., Goldstein, J., Chang, C. H., Zervos, M., Fitzgerald, J. T., Dworkin, H. J. et al. (1997). Cardiac involvement in patients with chronic fatigue syndrome as documented with Holter and biopsy data in Birmingham, Michigan, 1991-1993. Infectious Diseases in Clinical Practice, 6, 327-333.
40. Levy, M. S., Power, M. H. and Kepler, E. J. (1946). The specificity of the 'water test' as a diagnostic procedure in Addison's disease. Journal of Clinical Endocrinology, 6, 607-632.
41. Lipton, S. A. (1991). Calcium channel antagonists and Human Immunodeficiency Virus coat-protein mediated neuronal injury. Annals of Neurology, 31, 110-114.
42. Martin, J. B. and Reichlin, S. (1987). Clinical Endocrinology, F. A. Davis, Philadelphia, PA.
43. May, A., Ophoff, R. A., Terwindt, G. M. et al. (1995). Familial hemiplegic migraine locus on 19p13 is involved in the common forms of migraine with or without aura. Human Genetics, 96, 604-608.
44. Mayr, N., Baumgartner, C., Zeitlhofer, J. and Deecle, L. (1991). The sensitivity of transcranial cortical magnetic stimulation in detecting pyramidal lesions in clinically definite multiple sclerosis. Neurology, 41, 566-569.
45. McClave, S. A. and Snider, H. L. (1992). Use of indirect calorimetry in clinical nutrition. Nutrition in Clinical Practice, 7, 207-221.
46. Mohri, M., Koyanagi, M., Egashira, K., Tagawa, H., Ichiki, T. et al. (1998). Angina pectoris caused by microvascular spasm. Lancet, 351, 1165-1169.
47. Narahashi, T. (1996). Neuronal ion channels as the target sites of insecticides. Pharmacology & Toxicology, 79, 1-14.
48. Newsom-Davis, J. and Mills, K. R. (1993). Immunological associations of acquired neuromyotonia (Isacc's syndrome). Brain, 116, 453-469.
49. Nimura, H., Bachinski, L. L., Sangwatanroj, S., Watkins, H., Chudley, A. E., McKenna, W. et al. (1998). Mutations in the gene for cardiac myosin binding protein C in late and familial hypertrophic cardiomyopathy. New England Journal of Medicine, 338, 1248-1257.
50. O'Keane, V., O'Flynn, K., Lucey, J. and Dinan, T. G. (1992). Pyridostigmine induced growth hormone responses in healthy and depressed subjects: evidence for cholinergic supersensitivity in depression. Psychological Medicine, 22, 55-60.
51. Parker, L. N., Levin, E. R. and Lifrak, E. T. (1985). Evidence for adrenocortical adaptation to severe illness. Journal of Clinical Endocrinology and Metabolism, 60, 947-952.
52. Patterson, J., Aitchison, F., Wyper, D. J. et al. (1995). SPECT brain imaging in chronic fatigue syndrome. EOS - Journal of Immunology and Immunopharmacology, 15, 53-58.
53. Pearn, J. (1996). Chronic ciguatera: one organic cause of the chronic fatigue syndrome. Journal of Chronic Fatigue Syndrome, 2, 29-34.
54. Ptacek, L. J. (1998). The place of migraine as a channelopathy. Current Opinion in Neurology, 11, 217-226.
55. Ravenborg, M., Ligouri, R., Christiansen, P., Larsson, H. and Soelberg-Sorensen, P. (1992). The diagnostic reliability of magnetically evoked motor potentials in multiple sclerosis. Neurology, 42, 1296-1301.
56. Reichlin, S. and Vonsattel, J. P. (1991). Case records of the Massachusetts General Hospital: a 30 year old man with polydipsia, hypopituitarism and a mediastinal mass. New England Journal of Medicine, 324, 677-687.
57. Scott, L. (1998). Hypothalamic-pituitary-adrenal axis in chronic fatigue syndrome. PhD Thesis, University of London.
58. Serratrice, G. and Azulay, J. P. (1994). What is left of Morvan's fibrillary chorea? Revue Neurologique, 150, 257-265.
59. Sharma, H. S., Cervos-Navarro, J. and Dey, P. K. (1991). Increased blood-brain-barrier permeability following acute short-term swimming exercise in conscious normotensive young rats. Neuroscience Research, 10, 211-211.
60. Sharpstone, D. R., Murray, C. P., Ross, H. M. et al. (1996). Energy balance in asymptomatic HIV infection. AIDS, 10, 1377-1384.
61. Sonoda, Y., Gotow, T., Kuriyama, M. et al. (1994). Electrical myotonia of rabbit skeletal muscles by HMG-CoA reductase inhibitors. Muscle and Nerve, 17, 891-897.
62. Sorbi, M. J., Maassen, G. H. and Spierings, E. L. (1996). A time series analysis of daily hassles and mood changes in the 3 days before the migraine attack. Behavioral Medicine, 22(3), 103-113.
63. Soriani, S., Feggi, L., Battistella, P. A., Aranaldi, C., De Carlo, L. and Stipa, S. (1997). Interictal and ictal phase study with Tc 99m HMPAO brain SPECT in juvenile migraine with aura. Headache, 37, 31-36.
64. Soussi, B., Schersten, T., Waldenstorm, A. and Ronquist, G. (1993). Phosphocreatinine turnover and pH balance in forearm muscles of patients with syndrome X. Lancet, 341, 829-830.
65. Strupp, M., Bruing, R., Wu, R. H., Deimling, M., Reisez, M. and Brandt, T. (1998). Diffusion-weighted MRI in transient global amnesia: elevated signal intensity in the left mesial temporal lobe in 7 of 10 patients. Annals of Neurology, 43, 164-170.
66. Suzuki, T., Suzuki, N., Daynes, R. A. and Engelman, E. G. (1991). Dihydroepiandosterone enhances IL-2 production and cytotoxic effector function of human T cells. Clinical Immunology and Immunopathology, 61, 202-211.
67. Uncini, A., Lodi, R., DiMuzio, A., et al. Abnormal brain and muscle energy metabolism shown by 31P-MRS in familial hemiplegic migraine. Journal of Neurological Science, 129(2), 214-222.
68. Waldenström, A., Ronquist, G. and Lagerqvist, B. (1992). Angina pectoris patients with normal coronary angiograms but abnormal thallium perfusion scan exhibit low myocardial and skeletal muscle energy charge. Journal of International Medicine, 231, 327-331.
69. Watson, W. S., McCreath, G. T., Chaudhuri, A. and Behan, P. O. (1997). Possible cell membrane transport defect in chronic fatigue syndrome? Journal of Chronic Fatigue Syndrome, 3(3), 1-13.
70. Weidmann, B., Jansen, W. C., Bock, A., Assheur, J. and Tauchert, M. O. (1997). Technetium-99m-HMPAO brain SPECT in patients with Syndrome X. American Journal of Cardiology, 79, 959-961.