Highly diverse intergenic regions of the paramyxovirus simian virus 5 cooperate with the gene end U tract in viral transcription termination and can influence reinitiation at a downstream gene

Journal of Virology

Volumn 73, Issue 5, 1999, Pages 3904-3912

  Rassa, John C ^a   Parks, Griffith D ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DNA TEMPLATE; GENE SEQUENCE; MOLECULAR INTERACTION; NONHUMAN; PARAMYXOVIRUS; PRIORITY JOURNAL; PROMOTER REGION; SIMIAN VIRUS; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; VIRUS DNA CELL DNA INTERACTION; VIRUS TRANSCRIPTION;

EID: 0032928067     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.73.5.3904-3912.1999     Document Type: Article

References (35)

1. Banerjee, A. K., and S. Barik. 1992. Gene expression of vesicular stomatitis virus genome RNA. Virology 188:417-428.
2. Barr, J. N., S. P. J. Whelan, and G. W. Wertz. 1997. Role of the intergenic dinucleotide in vesicular stomatitis virus RNA transcription. J. Virol. 71: 1794-1801.
3. Barr, J. N., S. P. J. Whelan, and G. W. Wertz. 1997. Cis-acting signals involved in termination of vesicular stomatitis virus mRNA synthesis include the conserved AUAC and the U7 signal for polyadenylation. J. Virol. 71: 8718-8725.
4. Baumgartner, W., S. Krakowka, and J. R. Blakeslee. 1987. Persistent infection of Vero cells by paramyxoviruses. Intervirology 27:218-223.
5. Bousse, T., T. Takimoto, K. G. Murti, and A. Portner. 1997. Elevated expression of the human parainfluenza virus type 1 F gene downregulates HN expression. Virology 232:44-52.
6. Calain, P., and L. Roux. 1993. The rule of six, a basic feature for efficient replication of Sendai virus defective interfering RNA. J. Virol. 67:4822-4830.
7. Collins, P., R. M. Chancock, and K. McIntosh. 1996. Parainfluenza viruses, p. 1205-1241. In B. N. Fields, D. M. Knipe, and P. M. Howley (ed.). Virology, 3rd ed. Lippincott-Raven, New York, N.Y.
8. Collins, P. L., L. E. Dickens, A. Buckler-White, R. A. Olmsted, M. K. Spriggs, E. Camargo, and K. V. Coelingh. 1986. Nucleotide sequences for the gene junctions of human respiratory syncytial virus reveal distinctive features of intergenic structure and gene order. Proc. Natl. Acad. Sci. USA 83:4594-4598.
9. Elango, N., T. M. Varsanyi, J. Kovamees, and E. Norby. 1988. Molecular cloning and characterization of six genes, determination of gene order and intergenic sequences and leader sequence of mumps virus. J. Gen. Virol. 69:2893-2900.
10. Fuerst, T. R., E. G. Niles, F. W. Studier, and B. Moss. 1986. Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase. Proc. Natl. Acad. Sci. USA 85:8122-8126.
11. He, B., R. G. Paterson, C. D. Ward, and R. A. Lamb. 1997. Recovery of infectious SV5 from cloned DNA and expression of a foreign gene. Virology 237:249-260.
12. Hiebert, S. W., R. G. Paterson, and R. A. Lamb. 1985. Hemagglutinin neuraminidase protein of the paramyxovirus simian virus 5: nucleotide sequence of the mRNA predicts an N-terminal membrane anchor. J. Virol. 54:1-6.
13. Hiebert, S. W., R. G. Paterson, and R. A. Lamb. 1985. Identification and predicted sequence of a previously unrecognized small hydrophobic protein, SH, of the paramyxovirus simian virus 5. J. Virol. 54:744-751.
14. Hwang, L. N., N. Englund, and A. K. Pattnaik. 1998. Polyadenylation of vesicular stomatitis virus mRNA dictates efficient transcription termination at the intercistronic gene junctions. J. Virol. 72:1805-1813.
15. Iverson, L. E., and J. K. Rose. 1981. Localized attenuation and discontinued synthesis during vesicular stomatitis virus transcription. Cell 23:477-484.
16. Kolakofsky, D., T. Pelet, D. Garin, S. Housmann, J. Curran, and L. Roux. 1998. Paramyxovirus RNA synthesis and the requirement for hexamer genome length: the rule of six revisited. J. Virol. 72:891-899.
17. Kuo, L., R. Fearns, and P. L. Collins. 1996. The structurally diverse intergenic regions of respiratory syncytial virus do not modulate sequential transcription by a dicistronic minigenome. J. Virol. 70:6143-6150.
18. Kuo, L., H. Grosfeld, J. Cristina, M. G. Hill, and P. L. Collins. 1996. Effect of mutations in the gene-start and gene-end sequences motifs on transcription of monocistronic and dicistronic minigenomes of respiratory syncytial virus. J. Virol. 70:6892-6901.
19. Lamb, R. A., and D. Kolakofsky. 1996. Paramyxoviridae: the viruses and their replication, p. 1177-1204. In B. Fields, D. Knipe, and P. Howley (ed.), Virology, 3rd ed. Lippincott-Raven Publishers, Philadelphia, Pa.
20. Murphy, S. K., and G. D. Parks. 1997 Genome nucleotide lengths that are divisible by six are not essential but enhance replication of defective interfering RNAs of the paramyxovirus simian virus 5. Virology 232:145-157.
21. Parks, G. D. 1994. Mapping of a region of the paramyxovirus L protein required for the formation of a stable complex with the viral phosphoprotein P. J. Virol. 68:4862-4872.
22. Paterson, R. G., T. J. R. Harris, and R. A. Lamb. 1984. Analysis and gene assignment of mRNAs of a paramyxovirus, simian virus 5. Virology 138:310-323.
23. Paterson, R. G., T. J. R. Harris, and R. A. Lamb. 1984. Fusion protein of the paramyxovirus simian virus 5: nucleotide sequence of the mRNA predicts a highly hydrophobic glycoprotein. Proc. Natl. Acad. Sci. USA 81:6706-6710.
24. Pattnaik, A. K., L. A. Ball, A. W. Legrone, and G. W. Wertz. 1992. Infectious defective interfering particles of VSV from transcripts of a cDNA clone. Cell 69:1011-1020.
25. Perrotta, A. T., and M. D. Been. 1991. A pseudoknot-like structure required for efficient self-cleavage of hepatitis delta virus RNA. Nature (London) 350:434-436.
26. Rassa, J. C., and G. D. Parks. 1998. Molecular basis for naturally occurring elevated readthrough transcription across the M-F junction of the paramyxovirus SV5. Virology 247:274-286.
27. Rassa, J. C., and G. D. Parks. Unpublished observation.
28. Rose, J. K. 1980. Complete intergenic and flanking gene sequences from the genome of vesicular stomatitis virus. Cell 19:415-421.
29. Rose, J. K., L. Buonocore, and M. A. Whitt. 1991. A new cationic liposome reagent mediating nearly quantitative transfection of animal cells. BioTechniques 10:520-525.
30. Schubert, M., J. D. Keene, R. C. Herman, and R. A. Lazzarini. 1980. Site on the vesicular stomatitis virus genome specifying polyadenylation and the end of the L gene mRNA. J. Virol. 34:550-559.
31. Sheshberadaran, H., and R. A. Lamb. 1990. Sequence characterization of the membrane protein gene of paramyxovirus simian virus 5. Virology 176:234-243.
32. Stillman, E. A., and M. A. Whitt. 1997. Mutational analysis of the intergenic dinucleotide and the transcriptional start sequence of vesicular stomatitis virus (VSV) define sequences required for efficient termination and initiation of VSV transcripts. J. Virol. 71:2127-2137.
33. Stillman, E. A., and M. A. Whitt. 1998. The length and sequence composition of vesicular stomatitis virus intergenic regions affect mRNA levels and the site of transcription initiation. J. Virol. 72:5565-5572.
34. Thomas, S. M., R. A. Lamb, and R. G. Paterson. 1988. Two mRNAs that differ by two non templated nucleotides encode the amino co-terminal proteins P and V of the paramyxovirus SV5. Cell 54:891-902.
35. Wertz, G. W., V. P. Perepelitsa, and L. A. Ball. 1998. Gene arrangement attenuates expression and lethality of a nonsegmented negative strand RNA virus. Proc. Natl. Acad. Sci. USA 95:3501-3506.