2,6-difluorophenol as a bioisostere of a carboxylic acid: Bioisosteric analogues of γ-aminobutyric acid

Journal of Medicinal Chemistry

Volumn 42, Issue 2, 1999, Pages 329-332

  Qiu, Jian ^a   Stevenson, Scott H ^a   O'Beirne, Michael J ^a   Silverman, Richard B ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 (AMINOMETHYL) 2,6 DIFLUOROPHENOL; 4 (AMINOMETHYL) 2,6 DIFLUOROPHENOL; 4 AMINOBUTYRIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; DRUG SYNTHESIS; ENZYME INHIBITION; ENZYME SUBSTRATE; GABAERGIC SYSTEM; LIPOPHILICITY; NEUROPHARMACOLOGY; NEUROTRANSMISSION; NONHUMAN; SWINE;

4-AMINOBUTYRATE TRANSAMINASE; ANIMALS; BRAIN; CARBOXYLIC ACIDS; ENZYME INHIBITORS; GAMMA-AMINOBUTYRIC ACID; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; PHENOLS; SWINE;

EID: 0032927808     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980435l     Document Type: Article

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