Abnormalities of von Willebrand factor are also part of the prothrombotic state of Cushing's syndrome

Blood Coagulation and Fibrinolysis

Volumn 10, Issue 3, 1999, Pages 145-151

  Casonato, A ^a,b   Pontara, E ^a   Boscaro, M ^a   Sonino, N ^a   Sartorello, F ^a   Ferasin, S ^a   Girolami, A ^a  

^a UNIVERSITY OF PADUA MEDICAL SCHOOL   (Italy)

^b UNIVERSITY HOSPITAL OF PADOVA   (Italy)

Author keywords

Cushing's syndrome; Factor VIII; Prothrombic state; Von Willebrand factor

Indexed keywords

BLOOD CLOTTING FACTOR 8; GLUCOCORTICOID; HYDROCORTISONE; RISTOCETIN; VON WILLEBRAND FACTOR;

ADOLESCENT; ADULT; AGED; CLINICAL ARTICLE; CUSHING SYNDROME; FEMALE; HUMAN; HYDROCORTISONE BLOOD LEVEL; HYDROCORTISONE URINE LEVEL; HYPERCOAGULABILITY; MALE; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; REVIEW; THROMBOCYTE AGGREGATION; THROMBOSIS;

EID: 0032927792     PISSN: 09575235     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001721-199904000-00006     Document Type: Review

References (31)

1. Jaffe EA, Hower LW, Nachman RL. Synthesis of von Willebrand factor by cultured human endothelial cells. Proc Nat Acad Sci USA 1974; 71: 1906-1909.
2. Nachman R, Levine R, Jaffe EA. Synthesis of factor VIII antigen by cultured guinea pig megakaryocytes. J Clin Invest 1977; 60: 914-921.
3. Ruggeri ZM, Zimmerman TS. The complex multimeric composition of factor VIII/von Willebrand factor. Blood 1981; 57: 1140-1143.
4. Federici AB, Bader R, Pagani ML, Colibretti L, De Marco L, Mannucci PM. Binding of von Willebrand factor (vWF) to glycoprotein (GP) Ib and IIb-IIIa complex: affinity is related to multimeric size. Br J Haematol 1989; 73: 93-99.
5. Ozsolylu S, Strauss HS, Diamon LK. Effects of corticosteroids on coagulation of blood. Nature 1962; 195: 1214-1215.
6. Isacson S. Effect of prednisone in the coagulation and fibrinolytic systems. Scand J Haematol 1970; 7: 212- 216.
7. Jorgensen KA, Sorensen P, Freund L. Effect of glucocorticosteroids on some coagulation tests. Acta Haematol 1982; 68: 39-43.
8. Harrison RL, McKee PA. Estrogen stimulates von Willebrand factor production by cultured endothelial cells. Blood 1984; 63: 657-664.
9. Wagner DD. Cell biology of von Willebrand factor. Ann Rev Cell Biol 1990; 6: 217-246.
10. Sonino N, Zielezne M, Fava GA, Fallo F, Boscaro M. Risk factors and long term outcome in pituitary- dependent Cushing's disease. J Clin Endocrinol Metab 1996; 81: 2647-2652.
11. Sjoberg HE, Blomback M, Granberg PO. Thromboembolic complications, heparin treatment and increase in coagulation factors in Cushing's syndrome. Acta Med Scand 1976; 199: 95-98.
12. Patrassi GM, Sartori MT, Viero ML, Scarano L, Boscaro M, Girolami A. The fibrinolytic potential in patients with Cushing's disease: a clue to their hypercoagulable state. Blood Coag Fibrinol 1992; 3: 789-793.
13. Dal Bo Zanon R, Fornasiero L, Boscaro M, Cappellato G, Fabris F, Girolami A. Increased factor VIII associated activities in Cushing's syndrome: a probable hypercoagulable state. Thromb Haemost 1982; 47: 116-117.
14. Casonato A, Boscaro M, Pontara E, Bertomoro A, Scarpa E, Girolami A. Prothrombotic state in Cushing syndrome: increased levels and abnormal multimers organization of von Willebrand factor. Abstract 77. Annual Meeting of the Endocrine Society, Washington, 1995.
15. Patrassi GM, Dal Bo Zanon R, Boscaro M, Martinelli S, Girolami A. Further studies on the hypercoagulable state of patients with Cushing's syndrome. Thromb Haemost 1985; 54: 518-520.
16. Casonato A, Pontara E, Bertomoro A, Scarpa E, Sonino N, Girolami A. Abnormalities of primary haemostasis with consequent hypercoagulable state in patients with Cushing's syndrome. J Endocrinol Invest 1995; (suppl 5): 75.
17. Boscaro M, Rampazzo N, Sonino N, Merola A, Scanarini G, Mantero F. Corticotropin releasing hormone stimulation test: diagnostic aspects in Cushing's syndrome. J Endocrinol Invest 1987; 10: 297-302.
18. Casonato A, Fabris F, Vicariotto M, Girolami A. The evaluation of factor VIII antigen by means of a simple slide test. Am J Clin Pathol 1985; 84: 107-111.
19. Casonato A, Sartori MT, Pontara E, Zucchetto S, Girolami A. Impaired release of tissue plasminogen activator (t-PA) following DDAVP infusion in von Willebrand's disease with low platelet von Willebrand factor content. Blood Coag Fibrinol 1992; 3: 149-153.
20. Girolami A, Molaro G, Lazzarin M, Scarpa R, Brunetti A. A new congenital haemorrhagic condition due to the presence of abnormal factor X (factor X Friuli); study of a large kindred. Br J Haematol 1970; 19: 179-192.
21. Dalton RG, Dewar MS, Savidge GF. Hypothyroidism as a cause of acquired von Willebrand's disease. Lancet 1987; i: 1007-1009.
22. Boscaro M, Rampazzo A, Paoletta A. Pattern of ACTH response to oCRH in Cushing's disease: correlation with histological/immunocytochemical findings. Neuroendocrinology 1994; 60: 237-242.
23. Sporn LA, Marder VJ, Wagner DD. Von Willebrand factor released from Weibel-Palade bodies binds more avidly to extracellular matrix than that secreted constitutively. Blood 1987; 69: 1531-1534.
24. Weibel ER, Palade GE. New cytoplasmatic component in endothelial cells. J Cell Biol 1964; 23: 101-112.
25. Mannucci PM, Ruggeri ZM, Pareti FI, Capitanio A. DDAVP: a new pharmacological approach to the management of haemophilia A and von Willebrand disease. Lancet 1977; i: 869-872.
26. Charba D, Moake JL, Harris MA, Hester JP. Abnormalities of von Willebrand factor multimers in drug associated thrombotic microangiophathies. Am J Haematol 1993; 42: 268-277.
27. Nusinow SB, Federici AB, Zimmerman TS, Gurd JL. Increased von Willebrand factor in the plasma of patients with vasculitis. Arthritis Reum 1984; 27: 1405-1410.
28. Gralnick HR, Williams S, Morisato DK. Effect of the multimeric structure of the factor VIII/von Willebrand factor protein binding to platelets. Blood 1981; 58: 387-397.
29. Gader AMA, Clarckson AR, Cash JD. The plasminogen activator and factor VIII response to adrenaline, noradrenaline, isoprenaline and solbutamol in man. Thromb Res 1973; 3: 51-55.
30. Grant PJ, Tate GM, Williams NS, Prentice CRM. Intra-operative activation of coagulation: a stimulus to thrombosis mediated by vasopressin? Thromb Haemost 1986; 55: 104-108
31. Moake JL, Rudy LK, Troll JH, Weinstein MJ, Colannino NH. Unusually large von Willebrand factor multimers in chronic relapsing thrombotic thrombocytopenic purpura. N Engl J Med 1982; 307: 1432-1435.