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Volumn 31, Issue 2, 1999, Pages 691-701

Disruption of the Toxoplasma gondii bradyzoite-specific gene BAG1 decreases in vivo cyst formation

Author keywords

[No Author keywords available]

Indexed keywords

HEAT SHOCK PROTEIN; PHLEOMYCIN; PROTOZOAL PROTEIN;

EID: 0032927740     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.1999.01210.x     Document Type: Article
Times cited : (53)

References (44)
  • 1
    • 0002241311 scopus 로고
    • Expression and function of the low-molecular-weight heat shock proteins
    • Morimoto, R., Tissieres, A., and Georgopoulos, C. (eds). Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press
    • Arrigo, A., and Landry, J. (1994) Expression and function of the low-molecular-weight heat shock proteins. In The Biology of Heat Shock Proteins and Molecular Chaperones. Morimoto, R., Tissieres, A., and Georgopoulos, C. (eds). Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, pp. 335-373.
    • (1994) The Biology of Heat Shock Proteins and Molecular Chaperones , pp. 335-373
    • Arrigo, A.1    Landry, J.2
  • 2
    • 0029610921 scopus 로고
    • Restriction enzyme-mediated integration elevates transformation frequency and enables co-transfection of Toxoplasma gondii
    • Black, M., Seeber, F., Soldati, D., Kim, K., and Boothroyd, J.C. (1995) Restriction enzyme-mediated integration elevates transformation frequency and enables co-transfection of Toxoplasma gondii. Mol Biochem Parasitol 74: 55-63.
    • (1995) Mol Biochem Parasitol , vol.74 , pp. 55-63
    • Black, M.1    Seeber, F.2    Soldati, D.3    Kim, K.4    Boothroyd, J.C.5
  • 3
    • 0029143495 scopus 로고
    • Cloning and characterisation of a bradyzoite-specifically expressed gene (hsp30/bag1) of Toxoplasma gondii, related to genes encoding small heat-shock proteins of plants
    • Bohne, W., Gross, U., Ferguson, D.J., and Heesemann, J. (1995) Cloning and characterisation of a bradyzoite-specifically expressed gene (hsp30/bag1) of Toxoplasma gondii, related to genes encoding small heat-shock proteins of plants. Mol Microbiol 16: 1221-1230.
    • (1995) Mol Microbiol , vol.16 , pp. 1221-1230
    • Bohne, W.1    Gross, U.2    Ferguson, D.J.3    Heesemann, J.4
  • 4
    • 0027456961 scopus 로고
    • Induction of bradyzoite-specific Toxoplasma gondii antigens in gamma interferon-treated mouse macrophages
    • Bohne, W., Heesemann, J., and Gross, U. (1993) Induction of bradyzoite-specific Toxoplasma gondii antigens in gamma interferon-treated mouse macrophages. Infect Immun 61: 1141-1145.
    • (1993) Infect Immun , vol.61 , pp. 1141-1145
    • Bohne, W.1    Heesemann, J.2    Gross, U.3
  • 5
    • 0028220488 scopus 로고
    • Reduced replication of Toxoplasma gondii is necessary for induction of bradyzoite-specific antigens: A possible role for nitric oxide in triggering stage conversion
    • Bohne, W., Heesemann, J., and Gross, U. (1994) Reduced replication of Toxoplasma gondii is necessary for induction of bradyzoite-specific antigens: a possible role for nitric oxide in triggering stage conversion. Infect Immun 62: 1761-1767.
    • (1994) Infect Immun , vol.62 , pp. 1761-1767
    • Bohne, W.1    Heesemann, J.2    Gross, U.3
  • 6
    • 0030901972 scopus 로고    scopus 로고
    • Bradyzoite- specific gene expression in Toxoplasma gondii requires minimal genomic elements
    • Bohne, W., Wirsing, A., and Gross, U. (1997) Bradyzoite- specific gene expression in Toxoplasma gondii requires minimal genomic elements. Mol Biochem Parasitol 85: 89-98.
    • (1997) Mol Biochem Parasitol , vol.85 , pp. 89-98
    • Bohne, W.1    Wirsing, A.2    Gross, U.3
  • 7
    • 0032078233 scopus 로고    scopus 로고
    • Targeted disruption of the bradyzoite-specific gene BAG1 does not prevent tissue cyst formation in Toxoplasma gondii
    • Bohne, W., Hunter, C.A., White, M.W., Ferguson, D.J.P., Gross, U., and Roos, D.S. (1998) Targeted disruption of the bradyzoite-specific gene BAG1 does not prevent tissue cyst formation in Toxoplasma gondii. Mol Biochem Parasitol 92: 291-301.
    • (1998) Mol Biochem Parasitol , vol.92 , pp. 291-301
    • Bohne, W.1    Hunter, C.A.2    White, M.W.3    Ferguson, D.J.P.4    Gross, U.5    Roos, D.S.6
  • 8
    • 77957062984 scopus 로고
    • Forward and reverse genetics in the study of the obligate intracellular parasite Toxoplasma gondii
    • Adolph, K. (eds). New York: Academic Press
    • Boothroyd, J., Black, M., Kim, K., Pfefferkorn, E., Seeber, F., Sibley, L., and Soldati, D. (1995) Forward and reverse genetics in the study of the obligate intracellular parasite Toxoplasma gondii. In Methods in Molecular Genetics, Vol 6B. Adolph, K. (eds). New York: Academic Press.
    • (1995) Methods in Molecular Genetics , vol.6 B
    • Boothroyd, J.1    Black, M.2    Kim, K.3    Pfefferkorn, E.4    Seeber, F.5    Sibley, L.6    Soldati, D.7
  • 9
    • 0019831719 scopus 로고
    • Separation of Isospora (Toxoplasma) gondii cysts and cystozoites from mouse brain by continuous density-gradient centrifugation
    • Cornelissen, A., Overdulve, J., and Hoenderboom, J. (1981) Separation of Isospora (Toxoplasma) gondii cysts and cystozoites from mouse brain by continuous density-gradient centrifugation. J Parasitol 83: 103-108.
    • (1981) J Parasitol , vol.83 , pp. 103-108
    • Cornelissen, A.1    Overdulve, J.2    Hoenderboom, J.3
  • 10
    • 0029762391 scopus 로고    scopus 로고
    • Biodiversity in Toxoplasma gondii
    • Darde, M. (1996) Biodiversity in Toxoplasma gondii. Curr Top Microbiol Immunol 219: 27-41.
    • (1996) Curr Top Microbiol Immunol , vol.219 , pp. 27-41
    • Darde, M.1
  • 11
    • 0031958697 scopus 로고    scopus 로고
    • Structures of Toxoplasma gondii tachyzoites, bradyzoites and sporozoites and biology and development of tissue cysts
    • Dubey, J., Lindsay, D., and Speer, C. (1998) Structures of Toxoplasma gondii tachyzoites, bradyzoites and sporozoites and biology and development of tissue cysts. Clin Microbiol Rev 11: 267-299.
    • (1998) Clin Microbiol Rev , vol.11 , pp. 267-299
    • Dubey, J.1    Lindsay, D.2    Speer, C.3
  • 12
    • 0027161296 scopus 로고
    • Reduction of background problems in nonradioactive Northern and Southern blot analysis enables higher sensitivity than 32P-based hybridisation
    • Engler-Blum, G., Meier, M., Frank, J., and Muller, G. (1993) Reduction of background problems in nonradioactive Northern and Southern blot analysis enables higher sensitivity than 32P-based hybridisation. Anal Biochem 210: 235-244.
    • (1993) Anal Biochem , vol.210 , pp. 235-244
    • Engler-Blum, G.1    Meier, M.2    Frank, J.3    Muller, G.4
  • 13
    • 0029741131 scopus 로고    scopus 로고
    • Influence of antimicrobial agents on replication and stage conversion of Toxoplasma gondii
    • Gross, U., and Pohl, F. (1996) Influence of antimicrobial agents on replication and stage conversion of Toxoplasma gondii. Curr Top Microbiol Immunol 219: 235-245.
    • (1996) Curr Top Microbiol Immunol , vol.219 , pp. 235-245
    • Gross, U.1    Pohl, F.2
  • 14
    • 0031830788 scopus 로고    scopus 로고
    • Association of host cell intermediate filaments with Toxoplasma gondii cysts in murine astrocytes in vitro
    • Halonen, S.K., Weiss, L.M., and Chiu, F.C. (1998) Association of host cell intermediate filaments with Toxoplasma gondii cysts in murine astrocytes in vitro. Int J Parasitol 28: 815-823.
    • (1998) Int J Parasitol , vol.28 , pp. 815-823
    • Halonen, S.K.1    Weiss, L.M.2    Chiu, F.C.3
  • 15
    • 0028886480 scopus 로고
    • Toxoplasma gondii comprises three clonal lineages: Correlation of parasite genotype with human disease
    • Howe, D.K., and Sibley, L.D. (1995) Toxoplasma gondii comprises three clonal lineages: correlation of parasite genotype with human disease. J Infect Dis 172: 1561- 1566.
    • (1995) J Infect Dis , vol.172 , pp. 1561-1566
    • Howe, D.K.1    Sibley, L.D.2
  • 17
    • 0024546325 scopus 로고
    • Identification of stage-specific antigens of Toxoplasma gondii
    • Kasper, L.H. (1989) Identification of stage-specific antigens of Toxoplasma gondii. Infect Immun 57: 668-672.
    • (1989) Infect Immun , vol.57 , pp. 668-672
    • Kasper, L.H.1
  • 18
    • 0000963110 scopus 로고
    • Toxoplasma gondii and toxoplasmosis
    • Warren, K. (ed). Boston, MA: Blackwell Scientific Publications
    • Kasper, L., and Boothroyd, J. (1993) Toxoplasma gondii and toxoplasmosis. In Immunology and Molecular Biology of Parasitic Infections. Warren, K. (ed). Boston, MA: Blackwell Scientific Publications, pp. 269-301.
    • (1993) Immunology and Molecular Biology of Parasitic Infections , pp. 269-301
    • Kasper, L.1    Boothroyd, J.2
  • 19
    • 0021813579 scopus 로고
    • Recognition and characterisation of stage-specific oocyst/sporozoite antigens of Toxoplasma gondii by human antisera
    • Kasper, L., and Ware, P. (1985) Recognition and characterisation of stage-specific oocyst/sporozoite antigens of Toxoplasma gondii by human antisera. J Clin Invest 75: 1570- 1577.
    • (1985) J Clin Invest , vol.75 , pp. 1570-1577
    • Kasper, L.1    Ware, P.2
  • 20
    • 0027730341 scopus 로고
    • Gene replacement in Toxoplasma gondii with chloramphenicol acetyltransferase as selectable marker
    • Kim, K., Soldati, D., and Boothroyd, J.C. (1993) Gene replacement in Toxoplasma gondii with chloramphenicol acetyltransferase as selectable marker. Science 262: 911-914.
    • (1993) Science , vol.262 , pp. 911-914
    • Kim, K.1    Soldati, D.2    Boothroyd, J.C.3
  • 21
    • 0026901767 scopus 로고
    • Toxoplasmic encephalitis in AIDS
    • Luft, B., and Remington, J. (1992) Toxoplasmic encephalitis in AIDS. Clin Infect Dis 15: 211-222.
    • (1992) Clin Infect Dis , vol.15 , pp. 211-222
    • Luft, B.1    Remington, J.2
  • 22
    • 0029931077 scopus 로고    scopus 로고
    • An immunohistochemical method for detecting bradyzoite antigen (BAG5) in Toxoplasma gondii-infected tissues cross-reacts with a Neospora caninum bradyzoite antigen
    • McAllister, MM., Parmley, S.F., Weiss, L.M., Welch, V.J., and McGuire, A.M. (1996) An immunohistochemical method for detecting bradyzoite antigen (BAG5) in Toxoplasma gondii-infected tissues cross-reacts with a Neospora caninum bradyzoite antigen. J Parasitol 82: 354-355.
    • (1996) J Parasitol , vol.82 , pp. 354-355
    • McAllister, M.M.1    Parmley, S.F.2    Weiss, L.M.3    Welch, V.J.4    McGuire, A.M.5
  • 23
    • 0021340963 scopus 로고
    • Immune response of mice to ingested Toxoplasma gondii: A model of toxoplasma infection acquired by ingestion
    • McLeod, R., Estes, R.G., Mack, D.G., and Cohen, H. (1984) Immune response of mice to ingested Toxoplasma gondii: a model of toxoplasma infection acquired by ingestion. J Infect Dis 149: 234-244.
    • (1984) J Infect Dis , vol.149 , pp. 234-244
    • McLeod, R.1    Estes, R.G.2    Mack, D.G.3    Cohen, H.4
  • 24
    • 0029778228 scopus 로고    scopus 로고
    • Immunogenetics in pathogenesis of and protection against toxoplasmosis
    • McLeod, R., Johnson, J., Estes, R., and Mack, D. (1996) Immunogenetics in pathogenesis of and protection against toxoplasmosis. Curr Top Microbiol Immunol 219: 95-112.
    • (1996) Curr Top Microbiol Immunol , vol.219 , pp. 95-112
    • McLeod, R.1    Johnson, J.2    Estes, R.3    Mack, D.4
  • 25
    • 0024447404 scopus 로고
    • Genetic regulation of early survival and cyst number after peroral Toxoplasma gondii infection of A × B/B × A recombinant inbred and B10 congenic mice
    • McLeod, R., Skamene, E., Brown, C.R., Eisenhauer, P.B., and Mack, D.G. (1989) Genetic regulation of early survival and cyst number after peroral Toxoplasma gondii infection of A × B/B × A recombinant inbred and B10 congenic mice. J Immunol 143: 3031-3034.
    • (1989) J Immunol , vol.143 , pp. 3031-3034
    • McLeod, R.1    Skamene, E.2    Brown, C.R.3    Eisenhauer, P.B.4    Mack, D.G.5
  • 27
    • 0027930245 scopus 로고
    • Molecular characterisation of a 65-kilodalton Toxoplasma gondii antigen expressed abundantly in the matrix of tissue cysts
    • Parmley, S.F., Yang, S., Harth, G., Sibley, L.D., Sucharczuk, A., and Remington, J.S. (1994) Molecular characterisation of a 65-kilodalton Toxoplasma gondii antigen expressed abundantly in the matrix of tissue cysts. Mol Biochem Parasitol 66: 283-296.
    • (1994) Mol Biochem Parasitol , vol.66 , pp. 283-296
    • Parmley, S.F.1    Yang, S.2    Harth, G.3    Sibley, L.D.4    Sucharczuk, A.5    Remington, J.S.6
  • 28
    • 0028783843 scopus 로고
    • Cloning of a bradyzoite-specific gene of Toxoplasma gondii encoding a cytoplasmic antigen
    • Parmley, S.F., Weiss, L.M., and Yang, S. (1995) Cloning of a bradyzoite-specific gene of Toxoplasma gondii encoding a cytoplasmic antigen. Mol Biochem Parasitol 73: 253-257.
    • (1995) Mol Biochem Parasitol , vol.73 , pp. 253-257
    • Parmley, S.F.1    Weiss, L.M.2    Yang, S.3
  • 29
    • 0017753376 scopus 로고
    • Specific labelling of intracellular Toxoplasma gondii with uracil
    • Pfefferkorn, E.R., and Pfefferkorn, L.C. (1977a) Specific labelling of intracellular Toxoplasma gondii with uracil. J Protozool 24: 449-453.
    • (1977) J Protozool , vol.24 , pp. 449-453
    • Pfefferkorn, E.R.1    Pfefferkorn, L.C.2
  • 30
    • 0017336955 scopus 로고
    • Toxoplasma gondii: Specific labelling of nucleic acids of intracellular parasites in Lesch-Nyhan cells
    • Pfefferkorn, E.R., and Pfefferkorn, L.C. (1977b) Toxoplasma gondii: specific labelling of nucleic acids of intracellular parasites in Lesch-Nyhan cells. Exp Parasitol 41: 95-104.
    • (1977) Exp Parasitol , vol.41 , pp. 95-104
    • Pfefferkorn, E.R.1    Pfefferkorn, L.C.2
  • 31
    • 0032101958 scopus 로고    scopus 로고
    • Cloning and in vitro expression of TPK3, a Toxoplasma gondii homologue of shaggy/glycogen synthase kinase-3 kinases
    • Qin, C.-I., Tang, J., and Kim, K. (1998) Cloning and in vitro expression of TPK3, a Toxoplasma gondii homologue of shaggy/glycogen synthase kinase-3 kinases. Mol Biochem Parasitol 93: 273-283.
    • (1998) Mol Biochem Parasitol , vol.93 , pp. 273-283
    • Qin, C.-I.1    Tang, J.2    Kim, K.3
  • 32
    • 0028709114 scopus 로고
    • Molecular tools for genetic dissection of the protozoan parasite Toxoplasma gondii
    • Roos, D.S., Donald, R.G., Morrissette, N.S., and Moulton, A.L. (1994) Molecular tools for genetic dissection of the protozoan parasite Toxoplasma gondii. Methods Cell Biol 45: 27-63.
    • (1994) Methods Cell Biol , vol.45 , pp. 27-63
    • Roos, D.S.1    Donald, R.G.2    Morrissette, N.S.3    Moulton, A.L.4
  • 33
    • 0026706230 scopus 로고
    • Virulent strains of Toxoplasma gondii comprise a single clonal lineage
    • Sibley, L.D., and Boothroyd, J.C. (1992) Virulent strains of Toxoplasma gondii comprise a single clonal lineage. Nature 359: 82-85.
    • (1992) Nature , vol.359 , pp. 82-85
    • Sibley, L.D.1    Boothroyd, J.C.2
  • 34
    • 0029762684 scopus 로고    scopus 로고
    • Genetic basis of pathogenicity in toxoplasmosis
    • Sibley, L.D., and Howe, D.K. (1996) Genetic basis of pathogenicity in toxoplasmosis. Curr Top Microbiol Immunol 219: 3-15.
    • (1996) Curr Top Microbiol Immunol , vol.219 , pp. 3-15
    • Sibley, L.D.1    Howe, D.K.2
  • 35
    • 0027285317 scopus 로고
    • Toxoplasma gondii: Kinetics of bradyzoite-tachyzoite inter- conversion in vitro
    • Soete, M., Fortier, B., Camus, D., and Dubremetz, J.F. (1993) Toxoplasma gondii: kinetics of bradyzoite-tachyzoite inter- conversion in vitro. Exp Parasitol 76: 259-264.
    • (1993) Exp Parasitol , vol.76 , pp. 259-264
    • Soete, M.1    Fortier, B.2    Camus, D.3    Dubremetz, J.F.4
  • 36
    • 0027953833 scopus 로고
    • Experimental induction of bradyzoite-specific antigen expression and cyst formation by the RH strain of Toxoplasma gondii in vitro
    • Soete, M., Camus, D., and Dubremetz, J.F. (1994) Experimental induction of bradyzoite-specific antigen expression and cyst formation by the RH strain of Toxoplasma gondii in vitro. Exp Parasitol 78: 361-370.
    • (1994) Exp Parasitol , vol.78 , pp. 361-370
    • Soete, M.1    Camus, D.2    Dubremetz, J.F.3
  • 37
    • 0027310836 scopus 로고
    • Transient transfection and expression in the obligate intracellular parasite Toxoplasma gondii
    • Soldati, D., and Boothroyd, J.C. (1993) Transient transfection and expression in the obligate intracellular parasite Toxoplasma gondii. Science 260: 349-352.
    • (1993) Science , vol.260 , pp. 349-352
    • Soldati, D.1    Boothroyd, J.C.2
  • 38
    • 0029563801 scopus 로고
    • Complementation of a Toxoplasma gondii ROP1 knock-out mutant using phleomycin selection
    • Soldati, D., Kim, K., Kampmeier, J., Dubremetz, J.F., and Boothroyd, J.C. (1995) Complementation of a Toxoplasma gondii ROP1 knock-out mutant using phleomycin selection. Mol Biochem Parasitol 74: 87-97.
    • (1995) Mol Biochem Parasitol , vol.74 , pp. 87-97
    • Soldati, D.1    Kim, K.2    Kampmeier, J.3    Dubremetz, J.F.4    Boothroyd, J.C.5
  • 39
    • 0028809378 scopus 로고
    • Interconnection between organellar functions, development and drug resistance in the protozoan parasite, Toxoplasma gondii
    • Tomavo, S., and Boothroyd, J.C. (1995) Interconnection between organellar functions, development and drug resistance in the protozoan parasite, Toxoplasma gondii. Int J Parasitol 25: 1293-1299.
    • (1995) Int J Parasitol , vol.25 , pp. 1293-1299
    • Tomavo, S.1    Boothroyd, J.C.2
  • 40
    • 0026094273 scopus 로고
    • Characterisation of bradyzoite- specific antigens of Toxoplasma gondii
    • Tomavo, S., Fortier, B., Soete, M., Ansel, C., Camus, D., and Dubremetz, J.F. (1991) Characterisation of bradyzoite- specific antigens of Toxoplasma gondii. Infect Immun 59: 3750-3753.
    • (1991) Infect Immun , vol.59 , pp. 3750-3753
    • Tomavo, S.1    Fortier, B.2    Soete, M.3    Ansel, C.4    Camus, D.5    Dubremetz, J.F.6
  • 41
    • 0026694178 scopus 로고
    • Identification of Toxoplasma gondii bradyzoite-specific monoclonal antibodies
    • Weiss, L.M., LaPlace, D., Tanowitz, H.B., and Wittner, M. (1992) Identification of Toxoplasma gondii bradyzoite- specific monoclonal antibodies (letter). J Infect Dis 166: 213-215.
    • (1992) J Infect Dis , vol.166 , pp. 213-215
    • Weiss, L.M.1    Laplace, D.2    Tanowitz, H.B.3    Wittner, M.4
  • 43
    • 2642654218 scopus 로고    scopus 로고
    • Bradyzoite development in Toxoplasma gondii and the hsp70 stress response
    • Weiss, L.M., Ma, Y.F., Takvorian, P.M., Tanowitz, H.B., and Wittner, M. (1998) Bradyzoite development in Toxoplasma gondii and the hsp70 stress response. Infect Immun 66: 3295-3302.
    • (1998) Infect Immun , vol.66 , pp. 3295-3302
    • Weiss, L.M.1    Ma, Y.F.2    Takvorian, P.M.3    Tanowitz, H.B.4    Wittner, M.5
  • 44
    • 0028953166 scopus 로고
    • Toxoplasma gondii: Identification and characterisation of a cyst molecule
    • Zhang, Y.W., and Smith, J.E. (1995) Toxoplasma gondii: identification and characterisation of a cyst molecule. Exp Parasitol 80: 228-233.
    • (1995) Exp Parasitol , vol.80 , pp. 228-233
    • Zhang, Y.W.1    Smith, J.E.2


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