Are thyroid function tests too frequently and inappropriately requested?

Journal of Endocrinological Investigation

Volumn 22, Issue 3, 1999, Pages 184-190

  Roti, Elio ^a   Gardini, E ^a   Magotti, M G ^a   Pilla, S ^a   Minelli, R ^a,d   Salvi, M ^a   Monica, C ^b   Maestri, D ^b   Cencetti, S ^b,e   Braverman, L E ^c  

^a UNIVERSITY OF PARMA   (Italy)

^b UNIVERSITY HOSPITAL OF PARMA   (Italy)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d Assoc Volontaria Promozione Ric T   (Italy)

^e POLICLINICO MONTELUCE   (Italy)

Author keywords

Combinations; Number; Results; Thyroid function tests

Indexed keywords

LIOTHYRONINE; THYROTROPIN; THYROXINE;

ARTICLE; COST EFFECTIVENESS ANALYSIS; DISEASE SEVERITY; FREE LIOTHYRONINE INDEX; FREE THYROXINE INDEX; HOSPITAL PATIENT; HUMAN; HYPERTHYROIDISM; HYPOTHYROIDISM; ITALY; LABORATORY TEST; LIOTHYRONINE BLOOD LEVEL; MAJOR CLINICAL STUDY; OUTPATIENT; THYROID FUNCTION TEST; THYROTROPIN BLOOD LEVEL; THYROXINE BLOOD LEVEL;

EID: 0032927668     PISSN: 03914097     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03343539     Document Type: Article

References (22)

1. Stockigt J.R. Serum thyrotropin and thyroid hormone measurements and assessment of thyroid hormone transport. In: Braverman L.E., Utiger R.D. (Eds.), Werner and Ingbar's The Thyroid, ed. 7. Lippincott-Raven Publ., Philadelphia, 1996, p. 377.
2. Nolan J.P., Tarsa N.J., DiBenedetto G. Case-finding for unsuspected thyroid disease: Costs and health benefits. Am. J. Clin. Pathol. 83: 346, 1985.
3. Ferro-Luzzi A., Leclercq C., Berardi D. Sistema informative nutrizionale. Relazione Scientifica elaborate per il Ministero della Sanità. Istituto Nazionale della Nutrizione, 1992.
4. Vanderpump M.P.J., Tunbridge M.W.G. The epidemiology of thyroid disease. In: Braverman L.E., Utiger R.D. (Eds.) Werner and Ingbar's The Thyroid, ed. 7. Lippincott-Raven Publ. Philadelphia, 1996, p. 474.
5. Lindsay R.S., Toft A.D. Hypothyroidism. Lancet 349: 413, 1997.
6. Lazarus J.H. Hyperthyroidism. Lancet 349: 339, 1997.
7. Eggertsen R., Petersen K., Lundberg P.A., Nyström E., Lindstedt G. Screening for thyroid disease in a primary care unit with a thyroid stimulating hormone assay with a low detection limit. Br. Med. J. 297: 1586, 1988.
8. Feldkamp C.S., Carey J.L. An algorithmic approach to thyroid function testing in a managed care setting. Am. J. Clin. Pathol. 105: 11, 1996.
9. Surks M.I., Ocampo E. Subclinical thyroid disease. Am. J. Med. 100: 217, 1990.
10. Singer P.A., Cooper D.S., Levy E.G., Ladenson P.W., Braverman L.E., Daniels G., Greenspan F.S., McDougall I.R., Nikolai T.F. Treatment guidelines for patients with hyperthyroidism and hypothyroidism. JAMA 273: 808, 1995.
11. DeGroot L.J., Mayor G. Admission screening by thyroid function tests in an acute general care teaching hospital. Am. J. Med. 93: 558, 1992.
12. Bauer D.C., Brown A.N. Sensitive thyrotropin and free thyroxine testing in out-patients. Are both necessary? Arch. Intern. Med. 156: 2333, 1996.
13. Small M., Buchanan L., Evans R. Value of screening thyroid function in acute medical admission to hospital. Clin. Endocrinol. (Oxf.) 32: 185, 1990.
14. John R., Henley R., Lloyd G., Elder G. Evaluation of a new strategy for detection of thyroid dysfunction in the routine laboratory. Clin. Chem. 34: 1110, 1988.
15. Spencer C., Eigen A., Shen D., Duda M., Qualls S., Weiss S., Nicoloff S. Specificity of sensitive assays of thyrotropin (TSH) used to screen for thyroid disease in hospitalized patients. Clin. Chem. 33: 1391, 1987.
16. Bagchi N., Brown T.R., Parish R.P. Thyroid dysfunction in adults over age 55 years: a study in an urban United States community. Arch. Intern. Med. 150: 785, 1990.
17. Roti E., Gardini E., d'Amato L., Salvi M., Robuschi G., Manfredi A., Dallara G., Pino S., Guazzi A.M., Gnudi A., Braverman L.E. Goiter size and thyroid function in an endemic goiter area in northern Italy. J. Clin. Endocrinol. Metab. 63: 558, 1986.
18. Sawin C.T., Geller A., Kaplan M.M., Bacharach P., Wilson P.W.F., Hershmann J.M. Low serum thyrotropin (thyroid-stimulating hormone) in older persons without hyperthyroidism. Arch. Intern. Med. 151: 165, 1991.
19. Ehrmann D.A., Weinberg M., Same D.H. Limitations to the use of a sensitive assay for serum thyrotropin in the assessment of thyroid status. Arch. Intern. Med. 149: 369, 1989.
20. de los Santos E.T., Starich G.H., Mazzaferri E.I. Sensitivity, specificity, and cost-effectiveness of the sensitive thyrotropin assay in the diagnosis of thyroid disease in ambulatory patients. Arch. Intern. Med. 149: 526, 1989.
21. Ladenson P.W. Diagnosis of thyrotoxicosis. In: Braverman L.E., Utiger R.D. (Eds.) Werner and Ingbar's The Thyroid, ed. 7. Lippincott-Raven Publ., Philadelphia, 1996, p. 708.
22. Wartofsky L., Burman K.D. Alterations in thyroid function in patients with systemic illness: the euthyroid sick syndrome. Endocr. Rev. 3: 210, 1994.