Antagonistic effects of combination photosensitization by hypericin, meso-tetrahydroxyphenylchlorin (mTHPC) and Photofrin II® on Staphylococcus aureus

Drugs under Experimental and Clinical Research

Volumn 25, Issue 1, 1999, Pages 13-21

  Kubin, Andreas ^a,b,e   Wierrani, F ^a,c   Jindra, R H ^a,b   Loew, H G ^a,d   Grunberger W ^a,c   Ebermann, R ^a,d   Alth, G ^a,b  

^a Vienna Soc Photodynamic Diagn P   (Austria)

^b LUDWIG BOLTZMANN INSTITUTE FOR LUNG VASCULAR RESEARCH   (Austria)

^c KRANKENANSTALT RUDOLFSTIFTUNG   (Austria)

^d UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

^e NONE   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

HYPERICIN; MESOTETRAHYDROXYPHENYLCHLORIN; PHOTOFRIN; PHOTOFRIN II; PHOTOSENSITIZING AGENT; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; CONTROLLED STUDY; DRUG POTENTIATION; LIGHT; NONHUMAN; PHOTOSENSITIZATION; STAPHYLOCOCCUS AUREUS;

CELL CULTURE TECHNIQUES; CELL DIVISION; DRUG INTERACTIONS; LIGHT; LIGHTING; PHOTOSENSITIZING AGENTS; STAPHYLOCOCCUS AUREUS; TIME FACTORS;

EID: 0032927614     PISSN: 03786501     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Henderson B.W., Dougherty T.J. "Photodynamic Therapy". Marcel Dekker, Inc., New York, 1992.
2. Pass H. Photodynamic therapy in oncology: Mechanism and clinical use. J. Natl. Cancer Inst., 85, 443, 1993.
3. Hillegersberg R., Kort W.J., Wilson J.H.P. Current status of photodynamic therapy in oncology. Drugs, 48, 510, 1994.
4. Han G.S., Yoo D.J., Kim S.K., Shim S.C., Kang H.K. Photophysical properties of pyrazinpsoralen, a new monofunctional psoralen. Photochem. Photobiol., 64, 525, 1996.
5. Vanderwerf Q.M., Saxton R.E., Chang A., et al. Hypericin: A new laser phototargeting agent for human cancer cells. Laryngoscope, 106, 479, 1996.
6. Diwu Z. Novel therapeutic and diagnostic applications of hypocrellins and hypericins. Photochem. Photobiol., 61, 529, 1995.
7. Diwu Z., Lown W. Phototherapeutic potential of alternative photosensitizers to porphyrins. Pharmacol. Ther., 63, 1, 1994.
8. Bhatta N., Isaacson K., Bhatta K.M., Anderson R.R., Schiff I. Comparative study of different laser systems. Fertility Sterility, 61, 581, 1994.
9. Whitehurst C., Humphries J.D., Moore J.V. Development of an alternative light source to lasers for photodynamic therapy: 2. Comparative in vivo tumor response characteristic. Lasers in Medical Sci., 10, 121, 1995.
10. Ochsner M. Photophysical and photobiological processes in the photodynamic therapy of tumors. J. Photochem. Photobiol. B. Biology, 39, 1, 1997.
11. Malik Z., Gozhansky S., Nitzan Y. Effecfs of photoactivated hematoporphyrin derivative on bacteria and antibiotic resistance. Microbios, Lett., 21, 103, 1982.
12. Nitzan Y., Gutterman M., Malik Z., Ehrenberg B. Inactivation of Gram-negative bacteria by photosensitized porphyrins. Photochem, Photobiol., 55, 89, 1992.
13. Millson C.E., Wilson M., Macrobert A.J., Bown S.G. Ex-vivo treatment of gastric Helicobacter infection by photodynamic therapy. J. Photochem. Photobiol., B: Biology, 32, 59, 1996.
14. Merchat M., Spikes J.D., Bertoloni G., Jori G. Studies on the mechanism of bacterial photosensitization by meso-substituted cationic porphyrins. J. Photochem. Photobiol. B: Biology, 35, 149, 1996.
15. Laurence C., Lin L., Cook D., Wiesenhahn G., Wollowitz S. Photochemical inactivation of viruses and bacteria in human platelet concentrates. 12th Int. Cong. Photobiol. (Vienna, 1996) S237, p 172.
16. Kubin A., Alth G., Jindra H.R., Jessner G., Ebermann R. Wavelength dependent photorespond of biological systems using the photodynamic plantpigment Hypericin. J. Photochem. Photobiol. B: Biology, 36, 103, 1996.
17. Koren H., Schenk G.M., Jindra R.H. et al. Hypericin in phototherapy. J. Photochem. Photobiol. B: Biology, 36, 113, 1996.
18. Sureau F., Miskovsky P., Chinsky L., Turpin P.Y. Hypericininduced cell photosensitization involves an intracellular pH decrease. J. Am. Chem. Soc., 118, 9484, 1996.
19. Zang L.Y., Misra B.R., Misra H.P. Generation of free radicals during photosensitization of hypocrellin A and their effects on cardiac membranes. Photochem. Photobiol., 56, 453, 1992.