Characterization of the pharmacodynamic interaction between parent drug and active metabolite in vivo: Midazolam and α-OH-midazolam

Journal of Pharmacology and Experimental Therapeutics

Volumn 289, Issue 2, 1999, Pages 1067-1074

  Tuk, B ^a   Van Oostenbruggen, M F ^a   Herben, V M M ^a   Mandema, J W ^b   Danhof, M ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA HYDROXYMIDAZOLAM; MIDAZOLAM; PLASMA PROTEIN;

ANIMAL EXPERIMENT; CONFERENCE PAPER; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG INTERACTION; ELECTROENCEPHALOGRAPHY; GAS CHROMATOGRAPHY; INTRAVENOUS DRUG ADMINISTRATION; MALE; MODEL; NONHUMAN; PHARMACODYNAMICS; PRIORITY JOURNAL; RAT; RECEPTOR BINDING;

ALGORITHMS; ANIMALS; ANTI-ANXIETY AGENTS; BLOOD PROTEINS; DRUG INTERACTIONS; ELECTROENCEPHALOGRAPHY; MALE; MIDAZOLAM; MODELS, BIOLOGICAL; PROTEIN BINDING; RATS; RATS, WISTAR;

EID: 0032927364     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

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