Detection of multiple hepatic micrometastases in pancreatic adenocarcinoma with a solitary liver metastasis by direct sequencing of the K-ras gene: A case report

Surgery

Volumn 125, Issue 1, 1999, Pages 113-116

  Suwa, Hirofumi ^a   Hosotani, Ryo ^a   Okino, Takashi ^a   Monden, Kazunobu ^a   Arii, Shigeki ^a   Inoue, Kazutomo ^a   Kogire, Masafumi ^a   Ohshio, Gakuji ^a   Fukumoto, Manabu ^a   Imamura, Masayuki ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; CISPLATIN; FLUOROURACIL; PICIBANIL;

AGED; ARTICLE; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; FEMALE; GENE MUTATION; GENE SEQUENCE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LIVER METASTASIS; ONCOGENE K RAS; PANCREAS ADENOCARCINOMA; PRIORITY JOURNAL;

EID: 0032926719     PISSN: 00396060     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-6060(99)70298-9     Document Type: Article

References (5)

1. 1. Hayashi N, Arakawa H, Nagase H, Yanagisawa A, Kato Y, Ohta H, et al. Genetic diagnosis identifies occult lymph node metastases undetectable by the histopathological method. Cancer Res 1994;54:3853-6.
2. 2. Suwa H, Yoshimura T, Yamaguchi N, Kanehira K, Manabe T, Imamura M, et al. K-ras and p53 alterations in genomic DNA and transcripts of human pancreatic adenocarcinoma cell lines. Jpn J Cancer Res 1994;85:1005-14.
3. 3. Inoue S, Nakao A, Kasai Y, Harada A, Nonami T, Takagi H. Detection of hepatic micrometastasis in pancreatic adenocarcinoma patients by two-stage polymerase chain reaction/restriction fragment length polymorphism analysis. Jpn J Cancer Res 1995;86:626-30.
4. 4. Ishikawa S, Ohigashi H, Sasaki Y, Furukawa H, Kubuto T, Kameyama M, et al. Liver perfusion chemotherapy via both the hepatic artery and portal vein to prevent hepatic metastasis after extended pancreatectomy for adenocarcinoma of the pancreas. Am J Surg 1994;168:361-4.
5. 5. Shiratoi Y, Nakata R, Okano K, Komatsu Y, Shiina S, Kawase T, et al. Inhibition of hepatic metastasis of colon carcinoma by asialo GMI-positive cells in the liver. Hepatology 1992;16:469-78.