The 4A syndrome association with osteoporosis

Endocrine Journal

Volumn 46, Issue 1, 1999, Pages 227-230

  Özgen, A Gökhan ^a   Ercan, Ertuǧrul ^a   Özütemiz, Ömer ^a   Hamulu, Füsun ^a   Bayraktar, Firat ^a   Yilmaz, Candeǧer ^a  

^a EGE UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

Author keywords

4A syndrome; Allgrove syndrome; Osteoporosis; Sensorimotor neuropathy; Triple A syndrome

Indexed keywords

GLUCOCORTICOID;

ADRENAL CORTEX INSUFFICIENCY; ADULT; ARTICLE; AUTONOMIC DYSFUNCTION; BONE METABOLISM; CASE REPORT; CLINICAL FEATURE; DISEASE ASSOCIATION; ESOPHAGUS ACHALASIA; HUMAN; MALE; OSTEOPOROSIS; SENSORIMOTOR NEUROPATHY; SYNDROME;

EID: 0032926653     PISSN: 09188959     EISSN: None     Source Type: Journal    
DOI: 10.1507/endocrj.46.227     Document Type: Article

References (22)

1. Allgrove J, Clayden GS, Grant DB, McCauley JC (1978) Familial glucocorticoid deficiency with achalasia of the cardia and deficient tear production. Lancet I: 1284-1286.
2. Lanes R, Plotnick LP, Byrum TE (1980) Glucocorticoid and partial mineralocorticoid deficiency associated with achalasia. J Clin Endocrinol Metab 50: 268-270.
3. Geffner ME, Lippe BM, Kaplan SA, et al. (1983) Selective ACTH insensitivity, achalasia and alacrima: A multi-system disorder presenting in childhood. Pediatr Res 17: 532-536.
4. Ambrosino MM, Genieser NB, Bangaru BS, Sklar C, Becker MH (1986) The syndrome of achalasia of the oesophagus, ACTH insensitivity and alacrirna. Pediatr Radiol 16: 328-329.
5. Efrati Y, Mares J (1985) Infantile achalasia associated with deficient tear production. J Clin Gastroenterol 7: 413-415.
6. Enrich E, Aranoff G, Johnson WG (1987) Familial achalasia associated with adrenocortical insufficiency, alacrirna and neurological abnormalities. Am J Med Genet 26: 637-644.
7. Geffner ME, Lippe BM, Kaplan SA, Berquist WE, Bateman JB, Pateno VI, Seegan R (1983) Selective ACTH insensitivity, achalasia, and alacrima a multisystem disorder presenting in childhood. Pediatr Res 17: 532-536.
8. Moore PSJ, Couch RM, Perry YS, Shucket EP, Winter JSD (1991) Allgrove syndrome: An autosomal recessive syndrome of ACTH insensitivity, achalasia and alacrima. Clin Endocrinol 34: 107-114.
9. Lanes R, Plotnick LP, Bynum TE, Lee PA, Casella JF, Fox CE, Kowarski AA, Migeon CJ (1980) Glucocorticoid and partial mineralocorticoid deficiency associated with achalasia. J Clin Endocrinol Metab 50: 268-270.
10. Dumic M, Radica A, Stefanovic N, Murko Z (1987) Selective ACTH insensitivity associated with autonomic nervous system disorders and sensory polyneuropathy. Eur J Pediatr 146: 592-594.
11. Grant DB, Barnes ND, Dumic M, Ginalska-Malinowska M, Milla PJ, Petrykowski WV, Rowlatt RJ, Steendijk R, Wales JHK, Wender E (1993) Neurological and adrenal dysfunction in the adrenal insufficiency/alacrima/achalasia (3A) syndrome. Arch Dis Child 68: 779-782.
12. Espoti AD, Ambrosiani G, Giardia A, et al. (1985) sindrome familiare di ipoglicocorticoismo da insensibilita all ACTH con associata neurommiopatica distale. Minerva Pediatrica 37: 353-359.
13. Stuckey BG, Mastaglia FL, Reed WD, Pullan PT (1987) Glucocorticoid insufficiency, achalasia, alacrima with autonomic and motor neuropathy. Ann Intern Med 106: 62-64.
14. Gazarian M, Cowell CT, Bonney M, Grigor WG (1995) The "4A" syndrome: Adrenocortical insufficiency associated with achalasia, alacrima, autonomic and other neurological abnormalities. Eur J Pediatr 154: 18-23.
15. Dumic M, Radica A, Sabol Z, Plavsic V, Brkljacic Lj, Sarnavkov V, Vukovic J (1991) Adrenocorticotropic hormone insensitivity associated with autonomic nervous system disorders. Eur J Pediatr 150: 696-699.
16. Clark AJL, McLoughlin L, Grossman A (1993) Familial glucucorticoid deficiency associated with point mutation in the adrenocorticotropin receptor. Lancet 341: 461-462.
17. Campbell IW, Heading RC, Tothill P, Buist AS, Ewing DJ, Clarke BF (1977) Gastric emptying in diabetic autonomic neuropathy. Gut 18: 462-467.
18. Özgen AG, Aydin A, Kayalioǧlu M, Yilmaz C, Kumanlioǧlu K, Kabalak T, Tüzün M (1995) Evaluation of gastric and bladder emptying in diagnosis of diabetic autonomic neuropathy. T Klin J Gastroenterohepatology 6(4): 245-249.
19. Chen TL, Cone CM, Feldman D (1983) Effects of la, 25 dihydoxyvitamin D3 and glucocorticoids on the growth of rat and mouse osteoblast like bone cells. Calcif Tissue Int 35: 806-811.
20. McCulloch CAG, Tenenbaum HC (1986) Dexamethasone induces proliferation and terminal differentiation of osteogenic cells in tissue culture. Anat Rec 215: 397-402.
21. Rodan SB, Fischer MK, Egan JJ (1986) The effect of dexamethasone on parathyroid receptors and adenylate cyclase regulatory proteins. Gs and Gi in ROS 17/2.8 cells. Endocrinology 118: 2510-2518.
22. Leboy PS, Beresford JN, Devlin C (1991) Induction of osteoblast mRNAs in rat marrow stromal cell cultures. J Cell Physiol 146: 370-378.