Role for nitric oxide but not prostaglandins in acetylcholine-induced relaxation of rat cremaster third-order arterioles in 5-hour ischemia-reperfusion control rats

Chinese Journal of Physiology

Volumn 42, Issue 1, 1999, Pages 9-16

  Borsch, D M ^b   Cilento, E V ^a   Reilly, F D ^b  

^a WEST VIRGINIA UNIVERSITY   (United States)

^b WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acetylcholine; Arterioles; Atropine; Cremaster flaps; Ibuprofen; N G nitro L arginine methyl ester; Nitric oxide; Nitroprusside; Norepinephrine; Physiologic suffusate Po 2; Prostaglandins; Third order; Vasorelaxation

Indexed keywords

ACETYLCHOLINE; ARACHIDONIC ACID; ATROPINE; IBUPROFEN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITROPRUSSIDE SODIUM; NORADRENALIN; PROSTAGLANDIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTERIOLE; ARTERY DIAMETER; ARTERY DILATATION; ARTICLE; BLOOD VESSEL TONE; CONTROLLED STUDY; CREMASTER MUSCLE; NONHUMAN; OXYGEN TENSION; RAT; SHEAR STRESS;

EID: 0032924130     PISSN: 03044920     EISSN: 26660059     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Berthiaume, F. and Frangos, J.A. Flow-induced prostacyclin production is mediated by a pertussis toxin-sensitive G protein. FEBS Lett. 308: 277-279, 1992.
2. 2 during sympathetic escape in skeletal muscle. Am. J. Physiol. 254: H929-H936, 1988.
3. Bolme, P., Novotny, J., Uvnas, B. and Wright, P.G. Species distribution of sympathetic cholinergic vasodilator nerves in skeletal muscle. Acta Physiol. Scand. 78: 60-64, 1970.
4. Borsch, D.M., Cilento, E.V. and Reilly, F.D. The effects of two levels of vasomotor tone on acetylcholine- and sodium nitroprusside-induced relaxation of cremaster third-order arterioles in 5-hour ischemia-reperfusion control rats. Int. J. Microcirc. 17: 113-122, 1997.
5. Chant, A.D.B. and Barros D'Sa, A.A.B. Emergency Vascular Practice. London, Arnold, 1996, pp. 1-270.
6. De Wit, C., von Bismark, P. and Pohl, U. Mediator role of prostaglandins in acetylcholine-induced vasodilation and control of resting vascular diameter in the hamster cremaster microcirculation. J. Vasc. Res. 30: 272-278, 1993.
7. Fahraeus, R. The suspension stability of blood. Physiol. Rev. 9: 241-274, 1929.
8. Feldman, P.L., Griffith, O.W. and Stuehr, D.J. The surprising life of nitric oxide. C&EN December: 26-38, 1993.
9. Flavhan, N.A. Lysophosphatidylcholine modifies G protein-dependent signaling in porcine endothelial cells. Am. J. Physiol. 264: H722-H727, 1993.
10. Fleming, B.P., Barron, K.W., Howes, T.W. and Smith, J.K. Response of the microcirculation in the rat cremaster muscle to peripheral and central sympathetic stimulation. Circ. Res. (Supplement. II) 61: 26-31, 1987.
11. Friebel, M., Klotz, K.F., Ley, K., Gaehtgens, P. and Pries, A.R. Flow-dependent regulation of arteriolar diameter in rat skeletal muscle in situ: role of endothelium-derived relaxing factor and prostanoids. J. Physiol. 483.3: 715-726, 1995.
12. Furchgott, R.F. and Zawadzki, J. V. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288: 373-376, 1992.
13. Gil-Longo, J., Dufour, M.N. and Guillion & Lugnier, C. G-proteins in aortic endothelial cells and bradykinin-induced formation of nitric oxide. Eur. J. Pharmacol. 247: 119-125, 1993.
14. Gryglewski, R.J., Palmer, R.M.J. and Moncada, S. Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor. Nature 320: 454-456, 1986.
15. Hecker, M., Mulsch, A., Bassenge, E. and Busse, R. Vasoconstriction and increased flow: Two principal mechanisms of shear stress-dependent endothelial autacoid release. Am. J. Physiol. 265: H828-H833, 1993.
16. House, S.D. and Lipowsky, H.H. Microvascular hematocrit and red cell flux in rat cremaster muscle. Am. J. Physiol. 252: H21 1-H222, 1987.
17. Kaley, G., Koller, A., Rosenburg, J.M. and Messina, E. J. Regulation of arteriolar tone and responses via L-arginine pathway in skeletal muscle. Am. J. Physiol. 262: H987-H992, 1992.
18. Kaley, G., Rodenburg, J.M., Messina, E.J. and Wolin, M.S. Endothelium-associated vasodilators in rat skeletal muscle microcirculation. Am. J. Physiol. 256: H720-H725, 1989.
19. 2 . Circ. Res. 51: 711-721, 1982.
20. Koller, A. and Kaley, G. Prostaglandins mediate arteriolar dilation to increased blood flow velocity in skeletal muscle microcirculation. Circ. Res. 67: 529-534,1990.
21. Koller, A. and Kaley, G. Endothelial regulation of wall shear stress and blood flow in skeletal muscle microcirculation. Am. J. Physiol. 260: H862-H868, 1991.
22. Koller, A., Messina, E.J., Wolin, M.S. and Kaley, G. Endothelial impairment inhibits prostaglandin and EDRF-mediated arteriolar dilation in vivo. Am. J. Physiol. 257: H1966-H1970, 1989.
23. Koller, A., Messina, E.J., Wolin, M.S. and Kaley, G. Effects of endothelial impairment on arteriolar dilator responses in vivo. Am. J. Physiol. 257: H1485-H1489, 1989.
24. Koller, A., Seyedi, N., Gerritsen, M.E. and Kaley. G., EDRF released from microvascular endothelial cells dilates arterioles in vivo. Am. J. Physiol. 261: H128-H133, 1991.
25. Koller, A., Sun, D. and Kaley, G. Role of shear stress and endothelial prostaglandins in flow-and viscosity-induced dilation of arterioles in vivo. Circ. Res. 72: 1276-1284, 1993.
26. Ku, L., Davis, M. and Chillian, W.M. Endothelium-dependent, flow-induced dilation of isolated coronary arterioles. Am. J. Physiol. 259: H1063-H1070, 1990.
27. Kuroshima, N. and Labosky, D. Functional alteration of arteriole to vasodilators after ischemic in vivo microscopic study. In: Transactions of the 36th Annual Meeting of the Orthopaedic Research Society. The Orthopaedic Research Society, Park Ridge, IL, 1990, p 265.
28. Lipowski, H.H., Kovalcheck, S. and Zweifach, B.W. The distribution of blood rheological parameters in the microvasculature of cat mesentery. Circ. Res. 43: 738-749, 1978.
29. Malek, A.M. and Izumo, S. Molecular aspects of signal transduction of shear stress in the endothelial cell. J. Hypertension 12: 989-999, 1994.
30. Messina, E.J., Sun, D., Koller, A., Wolinand, M.S. and Kaley, G. Increases in oxygen tension evoke arteriolar constriction by inhibiting endothelial prostaglandin synthesis. Microvasc. Res. 48 : 151-160, 1994.
31. Moncada, S., Palmer, R.M. and Higgs, E.A. Nitric oxide: Physiological, Pathophysiology, and Pharmacology. Phrmacol. Rev. 43: 109-134, 1991.
32. G -monomethyl-L-arginine on arcade arterioles of rat spinotrapezius muscles. Am. J. Physiol. 261: H46-H52, 1991.
33. Ohyanagi, M., Nishigaki, K. and Faber, J.E. Interaction between microvascular alpha-1 and alpha-2 adrenoceptors and endothelium-derived relaxing factor. Circ. Res. 71: 188-200, 1992.
34. Pohl, U., Holtz, J., Busse, R. and Bassenge, E. Crucial role of endothelium in the vasodilator response to increased flow in vivo. Hypertension 8: 37-44, 1986.
35. Pohl, U. and Busse, R. Hypoxia stimulates release of endothelium-derived relaxant factor. Am. J. Physiol. 256: H1595-H1600, 1989.
36. Rees, D., Palmer, R.M.J., Schulz, R., Hodson, H.F. and Moncada, S. Characterization of three inhibitors of endothelial nitric oxide synthetase in vitro and in vivo. Br. J. Pharmacol. 101: 746-752, 1990.
37. Rubanyi, G.M. and Vanhoutte, P.M. Superoxide anionsand hyperoxia inactivate endothelium-derived relaxing factors. Am. J. Physiol. 250: H822-H827, 1986.
38. +2 signaling mechanism of vascular endothelial cells and their roles in oxidant-induced endothelial cell dysfunction. Am. J. Physiol. 262: H1617-H1630, 1992.
39. Shepherd, J.T. and Kutusic, Z.S. Endothelium-derived vasoactive factors: I. Endothelium-dependent relaxation. Hypertension. 18 (supplement III): 76-85, 1991.
40. Yamamoto, H., Bossaller, C., Cartwright, J. and Henry, P.D. Videomicroscopic demonstration of defective cholinergic arteriolar vasodilation in atherosclerotic rabbit. J. Clin. Invest. 81: 1752-1758, 1988.