Antiretroviral therapy with protease inhibitors in human immunodeficiency virus type 1- and human herpesvirus 8-coinfected patients

Journal of Medical Virology

Volumn 57, Issue 2, 1999, Pages 140-144

  De Milito, Angelo ^a   Catucci, Marinunzia ^d   Venturi, Giulietta ^d   Romano, Laura ^d   Incandela, Laura ^b   Valensin, Pier Egisto ^c   Zazzi, Maurizio ^c  

^a KAROLINSKA INSTITUTE   (Sweden)

^b Grosseto Hospital   (Italy)

^c General Hospital   (Italy)

^d NONE

Author keywords

Antiretroviral therapy; HHV 8; HIV 1; Kaposi's sarcoma

Indexed keywords

ANTIRETROVIRUS AGENT; CD4 ANTIGEN; PROTEINASE INHIBITOR;

ADULT; ARTICLE; CLINICAL ARTICLE; FEMALE; HUMAN; HUMAN CELL; HUMAN HERPESVIRUS 8; HUMAN IMMUNODEFICIENCY VIRUS 1; KAPOSI SARCOMA; MALE; MONONUCLEAR CELL; T LYMPHOCYTE; VIRUS INFECTION; VIRUS LOAD;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ANTI-HIV AGENTS; ANTIVIRAL AGENTS; DNA, VIRAL; DRUG THERAPY, COMBINATION; FEMALE; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 8, HUMAN; HIV INFECTIONS; HIV PROTEASE INHIBITORS; HIV-1; HUMANS; LEUKOCYTES, MONONUCLEAR; MALE; POLYMERASE CHAIN REACTION; RNA, VIRAL; SARCOMA, KAPOSI; TIME FACTORS; VIRAL LOAD; VIREMIA;

DNA VIRUSES; HERPESVIRIDAE; HERPESVIRUS 8; HUMAN HERPESVIRUS 8; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

EID: 0032923940     PISSN: 01466615     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9071(199902)57:2<140::AID-JMV9>3.0.CO;2-Y     Document Type: Article

References (20)

1. Ambroziak JA, Blackbourn DJ, Herndier BG, Glogau RG, Gullett JH, McDonald AR, Lennette ET, Levy JA. 1995. Herpes-like sequences in HIV-infected and uninfected Kaposi's sarcoma patients. Science 268:582-583.
2. + T-cell homeostasis and function in advanced HIV disease. Science 277:112-116.
3. Bigoni B, Dolcetti R, de Lellis L, Carbone A, Boiocchi M, Cassai E, Di Luca D. 1996. Human herpesvirus 8 is present in the lymphoid system of healthy persons and can reactivate in the course of AIDS. J Inf Dis 173:542-549.
4. Blum L, Pellet C, Agbalika F, Blanchard G, Morel P, Calvo F, Lebbe C. 1997. Complete remission of AIDS-related Kaposi's sarcoma associated with undetectable human herpesvirus-8 sequences during anti-HIV protease therapy. AIDS 11:1653-1655.
5. Carr A, Cooper DA. 1996. HIV protease inhibitors. AIDS 10:s151-s157.
6. Cesarman E, Knowles DM. 1997. Kaposi's sarcoma-associated herpes-virus: A lymphotropic human herpesvirus associated with Kaposi's sarcoma, primary effusion lymphoma, and multicentric Castleman's disease. Seminars Diagn Pathol 14:54-66.
7. Chang Y, Cesarman E, Pessin MS, Lee F, Culpepper J, Knowles DM, Moore PS. 1994. Identification of Herpesvirus-like DNA Sequences in AIDS-Associated Kaposi's Sarcoma. Science 266:1865-1869.
8. Conant MA, Opp KM, Poretz D, Mills RG. 1997. Reduction of Kaposi's sarcoma lesions following treatment of AIDS with ritonavir. AIDS 11:1300-1301.
9. De Milito A, Catucci M, Venturi G, Romano L, Valensin PE, Zazzi M, Almi P. 1996. HIV1 infection, homosexuality, and Kaposiassociated herpes-like DNA in peripheral blood mononuclear cells. Blood 87:3521-3522.
10. Dupin N, Krivine A, Calvez V, Gorin I, Franck N, Escande JP. 1997. No effect of protease inhibitor on clinical and virological evolution of Castleman's disease in an HIV-1-infected patient. AIDS 11: 1400-1401.
11. Lebbé C, Blum L, Pellet C, Blanchard G, Vérola O, Morel P, Danne O, Calvo F. 1998. Clinical and biological impact of antiretroviral therapy with protease inhibitors on HIV-related Kaposi's sarcoma. AIDS 12:F45-F49.
12. Martin JN, Ganem DE, Osmond DH, Page-Shafer KA, Maerae D, Kedes DH. 1998. Sexual transmission and the natural history of human herpesvirus 8 infection. N Engl J Med 338:948-954.
13. Melbye M, Cook PM, Hjalgrim H, Begtrup K, Simpson GR, Biggar RJ, Ebbesen P, Schulz TF. 1998. Risk factors for Kaposi's-sarcoma-associated herpesvirus (KSHV/HHV-8) seropositivity in a cohort of homosexual men, 1981-1996. Intl J Cancer 77:543-548.
14. Murphy M, Armstrong D, Sepkowitz KA, Ahkami RN, Myskowski PL. 1997. Regression of AIDS-related Kaposi's sarcoma following treatment with HIV1 protease inhibitor. AIDS 11:261-262.
15. Parra R, Leal M, Delgado J, Macias J, Rubio A, Gomez F, Soriano V, Sanchez-Quijano A, Pineda JA, Lissen E. 1998. Regression of invasive AIDS-related Kaposi's sarcoma following antiretroviral therapy. Clin Inf Dis 26:218-219.
16. Rizzieri DA, Liu J, Traweek ST, Miralles GD. 1997. Clearance of HHV8 from peripheral blood mononuclear cells with a protease inhibitor. Lancet 349:775-776.
17. Verbeek W, Frankel M, Miles S, Said J, Koeffler HP. 1998. Seroprevalence of HHV-8 antibodies in HIV-positive homosexual men without Kaposi's sarcoma and their clinical follow-up. Am J Clin Pathol 109:778-783.
18. Weir A, Wansbrough-Jones M. 1997. Mucosal Kaposi's sarcoma following protease inhibitor therapy in an HIV-infected patient. AIDS 11:1895-1897.
19. Whitby D, Howard MR, Tenant-Flowers M, Brink NS, Copas A, Boshoff C, Hatzioannou T, Suggett FE, Aldam DM, Denton AS. 1995. Detection of Kaposi's sarcoma associated herpesvirus in peripheral blood of HIV-infected individuals and progression to Kaposi's sarcoma. Lancet 346:799-802.
20. Zazzi M, Romano L, Brasini A, Valensin PE. 1993. Simultaneous amplification of multiple human immunodeficiency virus type 1 DNA sequences from clinical specimens by using nested-primer polymerase chain reaction. AIDS Res Hum Retroviruses 9:315-320.