A potential role of an intracellular signaling defect in neutrophil functional abnormalities and promotion of tissue damage in patients with localized juvenile periodontitis

Clinical Chemistry and Laboratory Medicine

Volumn 37, Issue 3, 1999, Pages 215-222

  Leino, Lasse ^a,c   Hurttia, Helena ^b  

^a UNIVERSITY OF TURKU   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

^c Astra Draco AB   (Sweden)

Author keywords

Diacylglycerol; Intracellular signaling; Localized juvenile periodontitis; Neutrophils

Indexed keywords

CELL SURFACE RECEPTOR; DIACYLGLYCEROL; DIACYLGLYCEROL KINASE; PROTEIN KINASE C;

CELL ACTIVITY; CELL ADHESION; CELL FUNCTION; CHEMOTAXIS; CHILDHOOD DISEASE; CONFERENCE PAPER; HUMAN; INFLAMMATORY DISEASE; METABOLISM; NEUTROPHIL; PERIODONTITIS; PHAGOCYTOSIS; PRIORITY JOURNAL; RESPIRATORY BURST; SERUM FACTOR; SIGNAL TRANSDUCTION; TISSUE INJURY;

CHILD; DIGLYCERIDES; HUMANS; NEUTROPHILS; PERIODONTITIS, JUVENILE; SIGNAL TRANSDUCTION;

EID: 0032922566     PISSN: 14346621     EISSN: None     Source Type: Journal    
DOI: 10.1515/CCLM.1999.040     Document Type: Conference Paper

References (85)

1. Baer PN. The case for periodontosis as a clinical entity. J Periodontol 1971; 42:516-9.
2. Gottlieb B. Die diffuse Atrophie des Alveolarknochens. Weitere Beiträge zur Kenntnis des Alveolarschwundes und dessen Wiedergutmachung durch Zementwachstum. Ztschr Stomatologie 1923; 21:195-262.
3. Ramfjord SP. The periodontal status of boys 11 to 17 years old in Bombay, India. J Periodontol 1961; 39:27-34.
4. Manson JD, Lehner T. Clinical features of juvenile periodontitis (periodontosis). J Periodontol 1974; 45: 636-40.
5. Liljenberg B, Lindhe J. Juvenile periodontitis. Some microbiological, histopathological and clinical characteristics. J Clin Periodontol 1980; 7:48-61.
6. Sandholm L, Saxen L. Local immunoglobulin synthesis in juvenile and adult periodontitis. J Clin Periodontol 1984; 11:459-66.
7. Newman MG, Socransky SS, Savitt ED, Propas DA, Crawford A. Studies of the microbiology of periodontosis. J Periodontol 1976; 47:373-9.
8. Cianciola LJ, Genco RJ, Patters MR, McKenna J, Van Oss CJ. Defective polymorphonuclear leukocyte function in a human periodontal disease. Nature 1977; 265:445-7.
9. Clark RA, Page RC, Wilde G. Defective neutrophil chemotaxis in juvenile periodontitis. Infect Immun 1977; 18: 694-700.
10. Malech HL, Gallin JI. Neutrophils in human diseases. N Engl J Med 1987; 317:687-94.
11. Attsröm R. Studies on neutrophil polymorphonuclear leukocytes at the dentogingival junction in gingival health and disease. J Periodontol 1971; 8 (Suppl):1-15.
12. Tempel TR, Snyderman R, Jordan HV, Mergenhagen SE. Factors from saliva and oral bacteria chemotactic for polymorphonuclear leukocytes: their possible role in gingival inflammation. J Periodontol 1970; 41:71-80.
13. Payne WA, Page RC, Ogilvie AL, Hall WB. Histopathologic features of the initial and early stages of experimental gingivitis in man. J Periodont Res 1975; 10:51-64.
14. Lindhe J, Hellden L. Neutrophil chemotactic activity elaborated by human dental plaque. J Periodont Res 1972; 7:297-303.
15. Wennström J, Heijl L, Lindhe J, Socransky S. Migration of gingival leukocytes mediated by dental plaque bacteria. J Periodont Res 1980; 15:363-72.
16. Leknes KN, Lie T, Boe OE, Selvig KA. A correlation study of inflammatory cell mobilisation in response to subgingival microbial colonization. J Periodontol 1997; 68:67-72.
17. Garant PR. Plaque-neutrophil interaction in monoinfected rats as visualized by transmission electron microscopy. J Periodontol 1976; 47:132-8.
18. Butcher EC. Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity. Cell 1991; 67:1033-6.
19. Genco RJ, Van Dyke TE, Park B, Ciminelli M, Horoszewicz H. Neutrophil chemotaxis impairment in juvenile periodontitis: evaluation of specificity, adherence, deformability, and serum factors. J Reticuloendothel Soc 1980; 28:81S-91S.
20. Agarwal S, Suzuki JB, Piesco NP, Aichelmann-Reidy MB. Neutrophil function in juvenile periodontitis: induction of adherence. Oral Microbiol Immunol 1994; 9:262-71.
21. Hurttia H, Saarinen K, Leino L. Increased adhesion of peripheral blood neutrophils from patients with localized juvenile parodontitis. J Periodont Res 1998; 33:292-7.
22. Lavine WS, Maderazo EG, Stolman J, Ward PA, Cogen RB, Greenblatt I, et al. Impaired neutrophil chemotaxis in patients with juvenile and rapidly progressing periodontitis. J Periodont Res 1979; 14:10-9.
23. Van Dyke TE, Horoszewicz HU, Cianciola LJ, Genco RJ. Neutrophil chemotaxis dysfunction in human periodontitis. Infect Immun 1980; 27:124-32.
24. Ellegaard B, Borregaard N, Ellegaard J. Neutrophil chemotaxis and phagocytosis in juvenile periodontitis. J Periodont Res 1984; 19:261-8.
25. Suzuki JB, Collison C, Falkler WA, Nauman RK. Immunologic profile of juvenile periodontitis. III. Neutrophil chemotaxis, phagocytosis, and spore germination. J Periodontol 1984; 55:461-7.
26. Van Dyke TE, Schweinebraten M, Cianciola LJ, Offenbacher S, Genco RJ. Neutrophil chemotaxis in families with localized juvenile periodontitis. J Periodont Res 1985; 20:503-14.
27. Agarwal S, Reynolds MA, Duckett LD, Suzuki JB. Altered free cytosolic calcium changes and neutrophil chemotaxis in patients with juvenile periodontitis. J Periodont Res 1989; 24:149-54.
28. Schenkein HA, Best AM, Gunsolley JC. Influence of race and periodontal clinical status on neutrophil chemotactic responses. J Periodont Res 1991; 26:272-5.
29. Daniel MA, McDonald G, Offenbacher S, Van Dyke TE. Defective chemotaxis and calcium response in localized juvenile periodontitis neutrophils. J Periodontol 1993; 64:617-21.
30. Singh S, Golub LM, Iacono VJ, Ramamurthy NS, Kaslick R. In vivo crevicular leukocyte response in humans to chemotactic challenge. J Periodontol 1984; 55:1-8.
31. Seymour KG, Watts TLP, Addison IE, Johnson B. An in vivo study of neutrophil locomotion in relation to periodontal disease status and local chlorhexidine. Oral Microbiol Immunol 1990; 5:95-7.
32. Palmer GD, Watts TLP, Addison IE. A skin window study of neutrophil migration in subjects with localized juvenile periodontitis. J Clin Periodontol 1993; 20:452-6.
33. Suzuki JB, Risom L, Falkler WA, Collison C, Bowers G. Effect of periodontal therapy on spontaneous lymphocyte response and neutrophil chemotaxis in localized and generalized juvenile periodontitis patients. J Clin Periodontol 1985; 12:124-34.
34. Leino L, Hurttia H, Peltonen E. Diacylglycerol in peripheral blood neutrophils from patients with localized juvenile periodontitis. J Periodont Res 1994; 29:334-8.
35. Van Dyke TE, Levine MJ, Tabak LA, Genco RJ. Reduced chemotactic peptide binding in juvenile periodontitis: a model for neutrophil function. Biochem Biophys Res Commun 1981; 100:1278-84.
36. Van Dyke TE, Levine MJ, Tabak LA, Genco RJ. Juvenile periodontitis as a model for neutrophil function: reduced binding of the complement chemotactic fragment, C5a. J Dent Res 1983; 62:870-2.
37. Van Dyke TE, Warbington M, Gardner M, Offenbacher S. Neutrophil surface protein markers as indicators of defective chemotaxis in LJP. J Periodontol 1990; 61:180-4.
38. Van Dyke TE, Warbington M, Gardner M, Offenbacher S. Neutrophil surface protein markers as indicators of defective chemotaxis in LJP. J Periodontol 1990; 61:180-4.
39. Perez HD, Kelly E, Elfman F, Armitage G, Winkler J. Defective polymorphonuclear leukocyte formyl peptide receptor(s) in juvenile periodontitis. J Clin Invest 1991; 87:971-6.
40. Tripathi SC, Van Dyke TE. Characterization of GP 110, a neutrophil surface protein. Infect Immun 1992; 60:3015-6.
41. Van Dyke TE, Zinney W, Winkel K, Taufiq A, Offenbacher D, Arnold RR. Neutrophil function in localized juvenile periodontitis. Phagocytosis, superoxide production and specific granule release. J Periodontol 1986; 57:703-8.
42. Zafiropoulos GG, Flores-de-Jacoby L, Czerch W, Kolb G, Markitziu A, Havemann K. Neutrophil function in patients with localized juvenile periodontitis and with rapidly progressive periodontitis. J Biol Buccale 1988; 16:151-6.
43. Katsuragi K, Takashiba S, Kurihara H, Murayama Y. Molecular basis of leukocyte adhesion molecules in early-onset periodontitis patients with decreased CD11/CD18 expression on leukocytes. J Periodontol 1994; 65:949-57.
44. Gutierrez J, Cutando A, Castillo AM, Liebana J, Baca P, Liodra JC. Phagocytosis and adhesiveness of peripheral blood polymorphonuclear leukocytes in patients with rapidly progressive periodontitis. J Oral Pathol 1991; 20:493-5.
45. Kimura S, Yonemura T, Hiraga T, Okada H. Flow cytometric evaluation of phagocytosis by peripheral blood polymorphonuclear leukocytes in human periodontal diseases. Arch Oral Biol 1992; 37:495-501.
46. Sigusch B, Klinger G, Holtz H, Suss J. In vitro phagocytosis by crevicular phagocytes in various forms of periodontitis. J Periodontol 1992; 63:496-501.
47. Mattout C, Mege JL, Capo C, Bongrand P, Fourel J. Impairment of neutrophil functions: study of a family with a case of juvenile periodontitis. J Parodont 1990; 9:297-308.
48. Henry CA, Winford TE, Laohapund P, Yotnuengnit P. Neutrophil chemi-luminescence and opsonic activities of young people with periodontitis in Thailand. Arch Oral Biol 1984; 29:623-7.
49. Åsman B, Engström P-E, Olsson T, Bergström K. Increased luminol enhanced chemiluminescence from peripheral granulocytes in juvenile periodontitis. Scand J Dent Res 1984; 92:218-23.
50. Åsman B, Bergström K, Wijkander P, Lockowandt B. Influence of plasma components on luminol-enhaced chemiluminescence from peripheral granulocytes in juvenile periodontitis. J Clin Periodontol 1986; 13:850-5.
51. Åsman B, Bergström K, Wijkander P, Lockowandt B. Peripheral PMN cell activity in relation to treatment of juvenile periodontitis. Scand J Dent Res 1988, 96:418-20.
52. Åsman B. Peripheral PMN cells in juvenile periodontitis. Increased release of elastase and oxygen radicals after stimulation with opsonized bacteria. J Clin Periodontol 1988; 15:360-4.
53. Shapira L, Borinsky R, Sela MN, Soskolne A. Superoxide formation and chemiluminescence of peripheral polymorphonuclear leukocytes in rapidly progressive periodontitis. J Clin Periodontol 1991; 18:44-8.
54. Åsman B, Bergström K, Expression of Fc-g-RIII and fibronectin in perpheral polymorphonuclear neutrophils with increased response to Fc stimulation in patients with juvenile periodontitis. Archs Oral Biol 1992; 37:991-5.
55. Leino L, Hurttia HM, Sorvajärvi K, Sewón LA. Increased respiratory burst activity is associated with normal expression of IgG-Fc-receptors and complement receptors in peripheral neutrophils from patients with juvenile periodontitis. J Periodont Res 1994; 29:179-84.
56. Repo H, Jansson S-E, Leirisalo-Repo M. Flow cytometric determination of CD11b upregulation in vivo. J Immunol Methods 1993; 164: 193-202.
57. Agarwal S, Suzuki JB. Altered neutrophil function in localized juvenile periodontitis: cellular defect or effect of immune mediators. J Periodont Res 1991; 26:276-8.
58. Meyle J. Neutrophil chemotaxis and serum concentration of tumor-necrosis-factor-α (TNFα). J Periodont Res 1993; 28:491-3.
59. Shapira L, Warbington M, Van Dyke TE. TNFα and IL-1β in serum of LJP patients with normal and defective neutrophil chemotaxis. J Periodont Res 1994; 29:371-3.
60. Tyagi SR, Uhlinger DJ, Lambeth JD, Champagne C, Van Dyke TE. Altered diacylglycerol level and metabolism in neutrophils from patients with localized juvenile periodontitis. Infect Immun 1992; 60:2481-7.
61. Kurihara H, Murayama Y, Warbington ML, Champagne CME, Van Dyke TE. Calcium-dependent protein kinase activity of neutrophils in localized juvenile periodontitis. Infect Immun 1993; 61:3137-42.
62. Hurttia HM, Pelto LM, Leino L. Evidence of an association between functional abnormalities and defective diacylglycerol kinase activity in peripheral blood neutrophils from patients with localized juvenile periodontitis. J Periodont Res 1997; 32:401-7.
63. Nishizuka Y. The role of protein kinase C in cell surface signal transduction and tumour promotion. Nature 1984; 308:693-8.
64. Cockcroft S, Allan D. The fatty acid composition of phosphatidyl inositol, phosphatidate and 1,2-diacylglycerol in stimulated human neutrophils. Biochem J 1984; 222:557-9.
65. Pettitt TR, Zaqqa M, Wakelam MJO. Epidermal growth factor stimulates distinct diradylglycerol species generation in Swiss 3T3 fibroblasts: evidence for a potential phosphatidyl choline-specific phospholipase C-catalysed pathway. Biochem J 1994; 298:655-60.
66. Hodgkin MN, Pettitt TR, Martin A, Wakelam MJO. Regulation of 'signalling diacylglycerol' in cells: the importance of diacylglycerol kinase. Biochem Soc Trans 1996; 24:991-4.
67. Singer SJ, Nicholson GL. The fluid mosaic model of the structure of cell membranes. Science 1972; 175:720-31.
68. Sheriff A, Luna EJ. Diacylglycerol-stimulated formation of actin nucleation sites at plasma membrane. Science 1992; 256:245-7.
69. Kanoh H, Yamada K, Sakane F. Diacylglycerol kinase: a key modulator of signal transduction? Trends Biochem Sci 1990; 15:47-50.
70. Kanoh H, Ono T. Utilization of diacylglycerol in phospholipid bilayers by pig brain diacylglycerol kinase and Rhizopus arrhizus lipase. J Biol Chem 1984; 259:11197-202.
71. MacDonald ML, Mack KF, Williams BW, King WC, Glomset JA. A membrane-bound diacylglycerol kinase that selectively phosphorylates arachidonoyl-diacylglycerol. Distinction from cytosolic diacylglycerol kinase and comparison with the membrane-bound enzyme from Eschericia coli. J Biol Chem 1988; 263:1584-92.
72. Hurttia H, Leino L. Subcellular localization of diacylglycerol kinase activity in stimulated and unstimulated human peripheral blood lymphocytes and neutrophils. Biochem Molec Biol Int 1996; 40:579-85.
73. Dougherty RW, Dubay GR, Niedel JE. Dynamics of the diradylglycerol responses of stimulated phagocytes. J Biol Chem 1989; 264:11263-9.
74. Ohtsuka T, Hiura M, Yoshida K, Okamura N, Ishibashi S. A diacylglycerol kinase inhibitor R59022 potentiates superoxide anion production and 46-kDa protein phosphorylation in Guinea pig polymorphonuclear leukocytes. J Biol Chem 1990; 265:15418-23.
75. Sullivan JA, Merritt JE, Budd JM, Booth RF, Hallam TJ. Effect of a selective protein kinase inhibitor, Ro 31-8425, on Mac-1 expression and adhesion of human neutrophils. Eur J Immunol 1994; 24:621-6
76. Yasui K, Yamazaki M, Miyabayashi M, Tsuno T, Komiyama A. Signal transduction pathway in human polymorphonuclear leukocytes for chemotaxis induced by a chemotactic factor. Distinct from the pathway for superoxide anion production. J Immunol 1994; 152:5922-9.
77. Wright CD, Stewart SF, Kuipers PJ, Hoffman MD, Devall LJ, Kennedy JA, et al. Selective regulation of human neutrophil functions by the cell activation inhibitor CI-959. J Leukoc Biol 1994; 55:443-51.
78. Merritt JE, Greener M, Hallam TJ, Swayne GT. The involvement of calcium and protein kinase C in modulating agonist-stimulated chemotaxis of human neutrophils. Cell Signal 1991; 3:73-7.
79. Keller HU, Niggli V. Selective effects of the PKC inhibitors Ro 31-8220 and CGP 41,251 on PMN locomotion, cell polarity and pinocytosis. J Cell Physiol 1994; 161:526-36.
80. Zheleznyak A, Brown EJ. Immunoglobulin-mediated phagocytosis by human monocytes requires protein kinase C activation. Evidence for protein kinase C translocation to phagosomes. J Biol Chem 1992; 267:12042-8.
81. de Chaffoy de Courcelles D, Roevens P, Van Belle H. R59022, a diacylglycerol kinase inhibitor. Its effect on diacylglycerol and thrombin-induced C kinase activation in the intact platelet. J Biol Chem 1985; 260:15762-70.
82. de Chaffoy de Courcelles D, Roevens P, Van Belle H, Kennis L, Somers Y, DeClerk F. The role of endogenously formed diacylglycerol in the propagation and termination of platelet activation. A biochemical and functional analysis using the novel diacylglycerol kinase inhibitor, R59949. J Biol Chem 1989; 264:3274-85.
83. Henson PM, Johnston RB. Tissue injury in inflammation. Oxidants, proteinases, and cationic proteins. J Clin Invest 1987; 79:669-74.
84. Weiss SJ. Tissue destruction by neutrophils. N Engl J Med 1989; 320:365-76.
85. Saari H, Suomalainen K, Lindy O, Konttinen YT, Sorsa T. Activation of latent human neutrophil collagenase by reactive oxygen species and serine proteases. Biochem Biophys Res Commun 1990; 171:979-87.